GJB6 (NM_001110220) Human Tagged ORF Clone
CAT#: RC225346L3
- LentiORF®
Lenti-ORF clone of GJB6 (Myc-DDK-tagged)-Human gap junction protein, beta 6, 30kDa (GJB6), transcript variant 2
"NM_001110220" in other vectors (4)
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | GJB6 |
Synonyms | CX30; DFNA3; DFNA3B; DFNB1B; ECTD2; ED2; EDH; HED; HED2 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC225346).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_001110220 |
ORF Size | 783 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001110220.2, NP_001103690.1 |
RefSeq Size | 2068 |
RefSeq ORF | 786 |
Locus ID | 10804 |
Protein Families | Druggable Genome, Transmembrane |
MW | 30.4 kDa |
Gene Summary | Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC317047 | GJB6 (untagged)-Human gap junction protein, beta 6, 30kDa (GJB6), transcript variant 2 |
USD 420.00 |
|
RC225346 | GJB6 (Myc-DDK-tagged)-Human gap junction protein, beta 6, 30kDa (GJB6), transcript variant 2 |
USD 420.00 |
|
RG225346 | GJB6 (GFP-tagged) - Human gap junction protein, beta 6, 30kDa (GJB6), transcript variant 2 |
USD 460.00 |
|
RC225346L4 | Lenti-ORF clone of GJB6 (mGFP-tagged)-Human gap junction protein, beta 6, 30kDa (GJB6), transcript variant 2 |
USD 620.00 |
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