Angiopoietin 2 (ANGPT2) (NM_001118888) Human Tagged ORF Clone
CAT#: RC225727L4
- LentiORF®
Lenti ORF clone of Human angiopoietin 2 (ANGPT2), transcript variant 3, mGFP tagged
"NM_001118888" in other vectors (4)
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | ANGPT2 |
Synonyms | AGPT2; ANG2 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC225727).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_001118888 |
ORF Size | 1332 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001118888.1, NP_001112360.1 |
RefSeq ORF | 1335 bp |
Locus ID | 285 |
Cytogenetics | 8p23.1 |
Protein Families | Druggable Genome, Secreted Protein |
MW | 50.96 kDa |
Gene Summary | 'This gene belongs to the angiopoietin family of growth factors. The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endothelial TEK receptor tyrosine kinase. Angiopoietin 2 is upregulated in multiple inflammatory diseases and is implicated in the direct control of inflammation-related signaling pathways. The encoded protein affects angiogenesis during embryogenesis and tumorigenesis, disrupts the vascular remodeling ability of angiopoietin 1, and may induce endothelial cell apoptosis. This gene serves a prognostic biomarker for acute respiratory distress syndrome. [provided by RefSeq, Aug 2020]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC318881 | ANGPT2 (untagged)-Human angiopoietin 2 (ANGPT2), transcript variant 3 |
USD 750.00 |
|
RC225727 | ANGPT2 (Myc-DDK-tagged)-Human angiopoietin 2 (ANGPT2), transcript variant 3 |
USD 420.00 |
|
RG225727 | ANGPT2 (GFP-tagged) - Human angiopoietin 2 (ANGPT2), transcript variant 3 |
USD 460.00 |
|
RC225727L3 | Lenti ORF clone of Human angiopoietin 2 (ANGPT2), transcript variant 3, Myc-DDK-tagged |
USD 620.00 |
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