bcl 6 (BCL6) (NM_001134738) Human Tagged ORF Clone
CAT#: RC226063L4
- LentiORF®
Lenti-ORF clone of BCL6 (mGFP-tagged)-Human B-cell CLL/lymphoma 6 (BCL6), transcript variant 3
"NM_001134738" in other vectors (4)
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | BCL6 |
Synonyms | BCL5; BCL6A; LAZ3; ZBTB27; ZNF51 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC226063).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_001134738 |
ORF Size | 1950 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001134738.1, NP_001128210.1 |
RefSeq ORF | 1953 bp |
Locus ID | 604 |
Cytogenetics | 3q27.3 |
Protein Families | Druggable Genome, Transcription Factors |
MW | 72.2 kDa |
Gene Summary | 'The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC326146 | BCL6 (untagged)-Human B-cell CLL/lymphoma 6 (BCL6), transcript variant 3 |
USD 1,100.00 |
|
RC226063 | BCL6 (Myc-DDK-tagged)-Human B-cell CLL/lymphoma 6 (BCL6), transcript variant 3 |
USD 480.00 |
|
RG226063 | BCL6 (GFP-tagged) - Human B-cell CLL/lymphoma 6 (BCL6), transcript variant 3 |
USD 530.00 |
|
RC226063L3 | Lenti-ORF clone of BCL6 (Myc-DDK-tagged)-Human B-cell CLL/lymphoma 6 (BCL6), transcript variant 3 |
USD 680.00 |
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