PCTAIRE2 (CDK17) (NM_001170464) Human Tagged ORF Clone

CAT#: RC230226

CDK17 (Myc-DDK-tagged)-Human cyclin-dependent kinase 17 (CDK17), transcript variant 2

Product Images

Western blot validation of overexpression lysate (Cat# LY433226) using anti-DDK antibody (Cat# TA50011-100). Left: Cell lysates from un-transfected HEK293T cells; Right: Cell lysates from HEK293T cells transfected with RC230226 using transfection reagent MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: CDK17
• Synonyms: PCTAIRE2; PCTK2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC230226 representing NM_001170464
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAAAAATTTAAGAGAAGGCTATCCCTCACACTCCGAGGAAGTCAGACTATTGATGAATCATTGTCTG
  AATTGGCTGAACAAATGACTATTGAAGAAAACAGCAGCAAGGATAATGAGCCTATTGTGAAGAATGGCAG
  GCCTCCAACGTCTCACAGTATGCATTCCTTCCTCCACCAGTACACAGGATCTTTCAAGAAGCCCCCATTG
  CGGAGACCACACAGTGTTATTGGAGGGAGCCTTGGCTCCTTCATGGCAATGCCCAGAAATGGAAGCAGAT
  TAGATATTGTTCATGAAAATCTAAAAATGGGATCAGATGGTGAGAGTGACCAAGCTTCTGGGACATCATC
  TGATGAAGTCCAGTCACCTACAGGTGTTTGTCTCAGAAATCGTATACATAGACGGATCTCAATGGAGGAT
  TTAAATAAGCGGTTATCACTGCCTGCAGACATCAGAATACCTGATGGATATCTTGAAAAGTTGCAGATAA
  ACAGTCCACCATTTGACCAACCAATGAGTCGAAGGTCTCGTAGAGCTTCCTTATCAGAAATTGGCTTTGG
  AAAAATGGAAACCTACATCAAATTGGAAAAGCTTGGAGAGGGTACATATGCAACAGTATATAAAGGAAGA
  AGTAAATTGACAGAGAATTTGGTGGCATTAAAAGAGATCCGATTGGAACATGAAGAAGGTGCACCCTGCA
  CAGCTATAAGAGAAGTTTCACTATTAAAGGATTTAAAACATGCAAATATAGTAACCTTACATGACATTGT
  TCACACAGATAAATCCTTGACTTTGGTGTTTGAGTATCTGGATAAAGACCTGAAACAGTACATGGATGAC
  TGTGGAAACATCATGAGTATGCACAACGTAAAGCTGTTTCTGTACCAAATTCTACGTGGTTTGGCATATT
  GCCATAGAAGAAAGGTATTGCATCGAGACTTGAAACCACAGAACCTCCTCATTAATGAGAAAGGAGAATT
  AAAGCTAGCAGATTTTGGACTAGCCCGAGCCAAGTCAGTTCCCACAAAGACCTACTCAAATGAAGTTGTC
  ACACTATGGTACCGGCCACCTGATGTGCTTCTTGGTTCCTCGGAGTACTCAACACAGATTGACATGTGGG
  GTGTTGGTTGCATTTTCTTTGAAATGGCTTCTGGAAGACCTTTATTTCCAGGATCAACCGTGGAAGATGA
  ACTGCACTTAATTTTCCGACTGCTAGGAACTCCATCTCAGGAAACTTGGCCAGGTATTTCTTCAAATGAG
  GAGTTCAAGAACTACAACTTTCCAAAATATAAACCACAGCCTCTAATTAACCACGCACCCAGGTTAGACT
  CTGAAGGAATTGAGTTGATAACAAAATTTCTTCAGTATGAATCTAAGAAAAGGGTTTCAGCTGAAGAGGC
  CATGAAACATGTGTACTTTCGAAGTCTGGGACCAAGAATACATGCTTTACCAGAAAGTGTATCAATATTC
  AGTTTGAAAGAGATTCAGTTGCAAAAGGACCCGGGTTTTCGAAATTCTTCTTATCCAGAGACAGGTGTGT
  TTGTCATAAACCATTTCACGTGTCGATCA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC230226 representing NM_001170464
  Red=Cloning site Green=Tags(s)
  
  MKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGRPPTSHSMHSFLHQYTGSFKKPPL
  RRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEVQSPTGVCLRNRIHRRISMED
  LNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGR
  SKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDD
  CGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVV
  TLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNE
  EFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIF
  SLKEIQLQKDPGFRNSSYPETGVFVINHFTCRS
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001170464
• ORF Size: 1569 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001170464.1, NM_001170464.2, NP_001163935.1
• RefSeq ORF: 1572
• Locus ID: 5128
• Protein Families: Druggable Genome, Protein Kinase
• MW: 60 kDa
• Gene Summary: The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It has similarity to a rat protein that is thought to play a role in terminally differentiated neurons. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jul 2010]