SLC9A6 (NM_001177651) Human Tagged ORF Clone

CAT#: RC230392

SLC9A6 (Myc-DDK-tagged)-Human solute carrier family 9 (sodium/hydrogen exchanger), member 6 (SLC9A6), transcript variant 3

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: SLC9A6
• Synonyms: MRSA; NHE6
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC230392 representing NM_001177651
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGACGAGGAGATCGTGTCCGAGAAGCAAGCCGAGGAGAGCCACCGGCAGGACAGCGCCAACCTGCTCA
  TCTTCATCCTGCTGCTCACCCTCACCATTCTCACAATCTGGCTCTTCAAGCACCGCCGGGCCCGCTTCCT
  GCACGAAACCGGCCTGGCTATGATTTATGGTCTTTTGGTGGGCCTTGTGCTTCGGTATGGCATTCATGTT
  CCGAGTGATGTAAATAATGTGACCCTGAGCTGTGAAGTGCAGTCAAGTCCAACTACCTTACTGGTAAATG
  TTAGTGGAAAATTTTATGAGTATATGCTGAAAGGAGAGATTAGTTCACATGAACTCAATAATGTTCAAGA
  TAATGAAATGCTTAGAAAGGTTACTTTTGATCCAGAAGTATTTTTCAACATATTACTTCCTCCTATCATA
  TTTTATGCAGGTTATAGCCTGAAAAGGAGACATTTTTTTCGAAATCTTGGGTCTATCCTAGCATACGCTT
  TTCTTGGAACAGCAATTTCTTGTTTCGTTATTGGGTCAATAATGTATGGCTGTGTAACGCTGATGAAGGT
  AACGGGACAACTTGCAGGAGATTTTTACTTTACAGATTGCCTACTGTTTGGTGCCATTGTATCAGCAACT
  GATCCAGTGACTGTTCTTGCTATATTCCACGAGCTTCAAGTTGATGTTGAACTCTATGCACTTCTTTTTG
  GTGAAAGTGTCCTCAATGATGCTGTTGCCATAGTGCTGTCCTCCTCAATAGTGGCATACCAGCCAGCTGG
  AGACAACAGTCACACCTTTGATGTCACAGCGATGTTCAAGTCTATTGGGATCTTCCTTGGAATCTTCAGT
  GGATCTTTTGCAATGGGTGCTGCTACTGGAGTGGTGACAGCTTTAGTGACAAAGTTCACCAAATTACGGG
  AGTTCCAGTTGTTGGAGACAGGCCTGTTCTTCTTGATGTCCTGGAGTACCTTCCTCTTGGCTGAAGCATG
  GGGCTTCACAGGTGTAGTTGCAGTATTGTTTTGTGGCATCACACAAGCACATTATACGTATAATAATTTG
  TCCACGGAGTCTCAGCATAGAACTAAACAGTTGTTTGAGCTTCTCAATTTCTTGGCAGAGAATTTCATCT
  TCTCCTACATGGGGCTGACACTGTTCACCTTCCAGAACCATGTCTTTAACCCAACATTTGTAGTAGGAGC
  ATTTGTTGCTATTTTCTTGGGAAGAGCTGCCAATATTTACCCCTTGTCCCTCTTACTTAATTTGGGTAGA
  AGAAGTAAGATTGGATCAAATTTTCAACACATGATGATGTTTGCTGGCCTTCGTGGTGCAATGGCATTTG
  CCTTGGCCATTCGAGATACTGCCACTTATGCACGGCAAATGATGTTCAGCACCACGCTTCTGATTGTGTT
  TTTTACCGTGTGGGTATTTGGTGGTGGCACCACTGCAATGCTGTCATGCTTGCATATCAGGGTTGGTGTT
  GATTCAGACCAAGAACACTTGGGTGTTCCTGAAAATGAAAGGAGAACTACCAAAGCAGAGAGTGCTTGGC
  TTTTCCGGATGTGGTACAACTTTGATCATAACTATCTGAAGCCTCTGCTGACCCACAGCGGGCCTCCGCT
  GACAACAACACTCCCTGCCTGCTGTGGACCCATCGCCAGGTGCCTCACCAGCCCCCAGGCTTACGAAAAC
  CAGGAACAGTTGAAAGATGATGATTCTGATCTTATTCTCAATGATGGTGACATCAGTTTGACATATGGAG
  ATTCTACTGTGAACACTGAACCGGCCACATCCAGCGCCCCAAGGAGATTTATGGGAAACAGTTCTGAAGA
  TGCCTTGGATCGGGAGCTTGCATTTGGGGACCATGAACTGGTCATTCGAGGAACACGCCTGGTTCTTCCA
  ATGGATGATTCTGAACCCCCGCTAAATTTGTTAGATAATACGAGACATGGTCCAGCC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC230392 representing NM_001177651
  Red=Cloning site Green=Tags(s)
  
  MDEEIVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHV
  PSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDPEVFFNILLPPII
  FYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLFGAIVSAT
  DPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFS
  GSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNL
  STESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGR
  RSKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRVGV
  DSDQEHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPIARCLTSPQAYEN
  QEQLKDDDSDLILNDGDISLTYGDSTVNTEPATSSAPRRFMGNSSEDALDRELAFGDHELVIRGTRLVLP
  MDDSEPPLNLLDNTRHGPA
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001177651
• ORF Size: 1947 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001177651.1, NP_001171122.1
• RefSeq Size: 4620
• RefSeq ORF: 1950
• Locus ID: 10479
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cardiac muscle contraction
• MW: 72.3 kDa
• Gene Summary: This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated with X-linked syndromic cognitive disability, Christianson type. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]