KIAA0319 (NM_001168374) Human Tagged ORF Clone

CAT#: RC230637

KIAA0319 (Myc-DDK-tagged)-Human KIAA0319 (KIAA0319), transcript variant 3

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: KIAA0319
• Synonyms: AAVR; DYLX2; DYX2; NMIG
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC230637 representing NM_001168374
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACTAGACTGGGCTGGCCGAGCCCATGTTGTGCCCGTAAGCAGTGCAGCGAGGGGAGGACATATTCCA
  ATGCAGTCATTTCACCTAACTTGGAAACCACCAGAATCATGCGGGTGTCTCACACCTTCCCTGTCGTAGA
  CTGCACGGCCGCTTGCTGTGACCTGTCCAGCTGTGACCTGGCCTGGTGGTTCGAGGGCCGCTGCTACCTG
  GTGAGCTGCCCCCACAAAGAGAACTGTGAGCCCAAGAAGATGGGCCCCATCAGGTCTTATCTCACTTTTG
  TGCTCCGGCCTGTTCAGAGGCCTGCACAGCTGCTGGACTATGGGGACATGATGCTGAACAGGGGCTCCCC
  CTCGGGGATCTGGGGGGACTCACCTGAGGATATCAGAAAGGACTTGACCTTTCTAGGCAAAGATTGGGGC
  CTAGAGGAGATGTCTGAGTACTCAGATGACTACCGGGAGCTGGAGAAGGACCTCTTGCAACCCAGTGGCA
  AGCAGGAGCCCAGAGGGAGTGCCGAGTACACGGACTGGGGCCTACTGCCGGGCAGCGAGGGGGCCTTCAA
  CTCCTCTGTTGGAGACAGTCCTGCGGTGCCAGCGGAGACGCAGCAGGACCCTGAGCTCCATTACCTGAAT
  GAGTCGGCTTCAACCCCTGCCCCAAAACTCCCTGAGAGAAGTGTGTTGCTTCCCTTGCCGACTACTCCAT
  CTTCAGGAGAGGTGTTGGAGAAAGAAAAGGCTTCTCAGCTCCAGGAACAATCCAGCAACAGCTCTGGAAA
  AGAGGTTCTAATGCCTTCCCATAGTCTTCCTCCGGCAAGCCTGGAGCTCAGCTCAGTCACCGTGGAGAAA
  AGCCCAGTGCTCACAGTCACCCCGGGGAGTACAGAGCACAGCATCCCAACACCTCCCACTAGCGCAGCCC
  CCTCTGAGTCCACCCCATCTGAGCTACCCATATCTCCTACCACTGCTCCCAGGACAGTGAAAGAACTTAC
  GGTATCGGCTGGAGATAACCTAATTATAACTTTACCCGACAATGAAGTTGAACTGAAGGCCTTTGTTGCG
  CCAGCGCCACCTGTAGAAACAACCTACAACTATGAATGGAATTTAATAAGCCACCCCACAGACTACCAAG
  GTGAAATAAAACAAGGACACAAGCAAACTCTTAACCTCTCTCAATTGTCCGTCGGACTTTATGTCTTCAA
  AGTCACTGTTTCTAGTGAAAACGCCTTTGGAGAAGGATTTGTCAATGTCACTGTTAAGCCTGCCAGAAGA
  GTCAACCTGCCACCTGTAGCAGTTGTTTCTCCCCAACTGCAAGAGCTCACTTTGCCTTTGACGTCAGCCC
  TCATTGATGGCAGCCAAAGTACAGATGATACTGAAATAGTGAGTTATCATTGGGAAGAAATAAACGGGCC
  CTTCATAGAAGAGAAGACTTCAGTTGACTCTCCCGTCTTACGCTTGTCTAACCTTGATCCTGGTAACTAT
  AGTTTCAGGTTGACTGTTACAGACTCGGACGGAGCCACTAACTCTACAACTGCAGCCCTAATAGTGAACA
  ATGCTGTGGACTACCCACCAGTTGCTAATGCAGGACCAAATCACACCATAACTTTGCCCCAAAACTCCAT
  CACTTTGAATGGAAACCAGAGCAGTGACGATCACCAGATTGTCCTCTATGAGTGGTCCCTGGGTCCTGGG
  AGTGAGGGCAAACATGTGGTCATGCAGGGAGTACAGACGCCATACCTTCATTTATCTGCAATGCAGGAAG
  GAGATTATACATTTCAGCTGAAGGTGACAGATTCTTCAAGGCAACAGTCTACTGCTGTGGTGACTGTGAT
  TGTCCAGCCTGAAAACAATAGACCTCCAGTGGCTGTGGCCGGCCCTGATAAAGAGCTGATCTTCCCAGTG
  GAAAGTGCTACCCTGGATGGGAGCAGCAGCAGCGATGACCACGGCATTGTCTTCTACCACTGGGAGCACG
  TCAGAGGCCCCAGTGCAGTGGAGATGGAAAATATTGACAAAGCAATAGCCACTGTGACTGGTCTCCAGGT
  GGGGACCTACCACTTCCGTTTGACAGTGAAAGACCAGCAGGGACTGAGCAGCACGTCCACCCTCACTGTG
  GCTGTGAAGAAGGAAAATAATAGTCCTCCCAGAGCCCGGGCTGGTGGCAGACATGTTCTTGTGCTTCCCA
  ATAATTCCATTACTTTGGATGGTTCAAGGTCTACTGATGACCAAAGAATTGTGTCCTATCTGTGGATCCG
  GGATGGCCAGAGTCCAGCAGCTGGAGATGTCATCGATGGCTCTGACCACAGTGTGGCTCTGCAGCTTACG
  AATCTGGTGGAGGGGGTGTACACTTTCCACTTGCGAGTCACCGACAGTCAGGGGGCCTCGGACACAGACA
  CTGCCACTGTGGAAGTGCAGCCAGACCCTAGGAAGAGTGGCCTGGTGGAGCTGACCCTGCAGGTTGGTGT
  TGGGCAGCTGACAGAGCAGCGGAAGGACACCCTTGTGAGGCAGCTGGCTGTGCTGCTGAACGTGCTGGAC
  TCGGACATTAAGGTCCAGAAGATTCGGGCCCACTCGGATCTCAGCACCGTGATTGTGTTTTATGTACAGA
  GCAGGCCGCCTTTCAAGGTTCTCAAAGCTGCTGAAGTGGCCCGAAATCTGCACATGCGGCTCTCAAAGGA
  GAAGGCTGACTTCTTGCTTTTCAAGGTCTTGAGGGTTGATACAGCAGGTTGCCTTCTGAAGTGTTCTGGC
  CATGGTCACTGCGACCCCCTCACAAAGCGCTGCATTTGCTCTCACTTATGGATGGAGAACCTTATACAGC
  GTTATATCTGGGATGGAGAGAGCAACTGTGAGTGGAGTATATTCTATGTGACAGTGTTGGCTTTTACTCT
  TATTGTGCTAACAGGAGGTTTCACTTGGCTTTGCATCTGCTGCTGCAAAAGACAAAAAAGGACTAAAATC
  AGGAAAAAAACAAAGTACACCATCCTGGATAACATGGATGAACAGGAAAGAATGGAACTGAGGCCCAAAT
  ATGGTATCAAGCACCGAAGCACAGAGCACAACTCCAGCCTGATGGTATCCGAGTCTGAGTTTGACAGTGA
  CCAGGACACAATCTTCAGCCGAGAAAAGATGGAGAGAGGGAATCCAAAGGTTTCCATGAATGGTTCCATC
  AGAAATGGAGCTTCCTTCAGTTATTGCTCAAAGGACAGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC230637 representing NM_001168374
  Red=Cloning site Green=Tags(s)
  
  MTRLGWPSPCCARKQCSEGRTYSNAVISPNLETTRIMRVSHTFPVVDCTAACCDLSSCDLAWWFEGRCYL
  VSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMMLNRGSPSGIWGDSPEDIRKDLTFLGKDWG
  LEEMSEYSDDYRELEKDLLQPSGKQEPRGSAEYTDWGLLPGSEGAFNSSVGDSPAVPAETQQDPELHYLN
  ESASTPAPKLPERSVLLPLPTTPSSGEVLEKEKASQLQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEK
  SPVLTVTPGSTEHSIPTPPTSAAPSESTPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVA
  PAPPVETTYNYEWNLISHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFVNVTVKPARR
  VNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEEKTSVDSPVLRLSNLDPGNY
  SFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTITLPQNSITLNGNQSSDDHQIVLYEWSLGPG
  SEGKHVVMQGVQTPYLHLSAMQEGDYTFQLKVTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELIFPV
  ESATLDGSSSSDDHGIVFYHWEHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTV
  AVKKENNSPPRARAGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLT
  NLVEGVYTFHLRVTDSQGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQLAVLLNVLD
  SDIKVQKIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADFLLFKVLRVDTAGCLLKCSG
  HGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVTVLAFTLIVLTGGFTWLCICCCKRQKRTKI
  RKKTKYTILDNMDEQERMELRPKYGIKHRSTEHNSSLMVSESEFDSDQDTIFSREKMERGNPKVSMNGSI
  RNGASFSYCSKDR
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001168374
• ORF Size: 3189 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001168374.1, NP_001161846.1
• RefSeq ORF: 3192
• Locus ID: 9856
• Protein Families: Transmembrane
• MW: 117.5 kDa
• Gene Summary: This gene encodes a transmembrane protein that contains a large extracellular domain with multiple polycystic kidney disease (PKD) domains. The encoded protein may play a role in the development of the cerebral cortex by regulating neuronal migration and cell adhesion. Single nucleotide polymorphisms in this gene are associated with dyslexia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]