PCDH11X (NM_001168361) Human Tagged ORF Clone

CAT#: RC230638

PCDH11X (Myc-DDK-tagged)-Human protocadherin 11 X-linked (PCDH11X), transcript variant f

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: PCDH11X
• Synonyms: PCDH-X; PCDH-Y; PCDH11; PCDH11Y; PCDH22; PCDHX; PPP1R119
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC230638 representing NM_001168361
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGACTTGTTGTCCGGGACGTACATTTTCGCGGTCCTGCTAGCATGCGTGGTGTTCCACTCTGGCGCCC
  AGGAGAAAAACTACACCATCCGAGAAGAAATGCCAGAAAACGTCCTGATAGGCGACTTGTTGAAAGACCT
  TAACTTGTCGCTGATTCCAAACAAGTCCTTGACAACTGCTATGCAGTTCAAGCTAGTGTACAAGACCGGA
  GATGTGCCACTGATTCGAATTGAAGAGGATACTGGTGAGATCTTCACTACTGGCGCTCGCATTGATCGTG
  AGAAATTATGTGCTGGTATCCCAAGGGATGAGCATTGCTTTTATGAAGTGGAGGTTGCCATTTTGCCGGA
  TGAAATATTTAGACTGGTTAAGATACGTTTTCTGATAGAAGATATAAATGATAATGCACCATTGTTCCCA
  GCAACAGTTATCAACATATCAATTCCAGAGAACTCGGCTATAAACTCTAAATATACTCTCCCAGCGGCTG
  TTGATCCTGACGTAGGAATAAACGGAGTTCAAAACTACGAACTAATTAAGAGTCAAAACATTTTTGGCCT
  CGATGTCATTGAAACACCAGAAGGAGACAAGATGCCACAACTGATTGTTCAAAAGGAGTTAGATAGGGAA
  GAGAAGGATACCTACGTGATGAAAGTAAAGGTTGAAGATGGTGGCTTTCCTCAAAGATCCAGTACTGCTA
  TTTTGCAAGTGAGTGTTACTGATACAAATGACAACCACCCAGTCTTTAAGGAGACAGAGATTGAAGTCAG
  TATACCAGAAAATGCTCCTGTAGGCACTTCAGTGACACAGCTCCATGCCACAGATGCTGACATAGGTGAA
  AATGCCAAGATCCACTTCTCTTTCAGCAATCTAGTCTCCAACATTGCCAGGAGATTATTTCACCTCAATG
  CCACCACTGGACTTATCACAATCAAAGAACCACTGGATAGGGAAGAAACACCAAACCACAAGTTACTGGT
  TTTGGCAAGTGATGGTGGATTGATGCCAGCAAGAGCAATGGTGCTGGTAAATGTTACAGATGTCAATGAT
  AATGTCCCATCCATTGACATAAGATACATCGTCAATCCTGTCAATGACACAGTTGTTCTTTCAGAAAATA
  TTCCACTCAACACCAAAATTGCTCTCATAACTGTGACGGATAAGGATGCGGACCATAATGGCAGGGTGAC
  ATGCTTCACAGATCATGAAATCCCTTTCAGATTAAGGCCAGTATTCAGTAATCAGTTCCTCCTGGAGACT
  GCAGCATATCTTGACTATGAGTCCACAAAAGAATATGCCATTAAATTACTGGCTGCAGATGCTGGCAAAC
  CTCCTTTGAATCAGTCAGCAATGCTCTTCATCAAAGTGAAAGATGAAAATGACAATGCTCCAGTTTTCAC
  CCAGTCTTTCGTAACTGTTTCTATTCCTGAGAATAACTCTCCTGGCATCCAGTTGACGAAAGTAAGTGCA
  ATGGATGCAGACAGTGGGCCTAATGCTAAGATCAATTACCTGCTAGGCCCTGATGCTCCACCTGAATTCA
  GCCTGGATTGTCGTACAGGCATGCTGACTGTAGTGAAGAAACTAGATAGAGAAAAAGAGGATAAATATTT
  ATTCACAATTCTGGCAAAAGATAACGGGGTACCACCCTTAACCAGCAATGTCACAGTCTTTGTAAGCATT
  ATTGATCAGAATGACAATAGCCCAGTTTTCACTCACAATGAATACAACTTCTATGTCCCAGAAAACCTTC
  CAAGGCATGGTACAGTAGGACTAATCACTGTAACTGATCCTGATTATGGAGACAATTCTGCAGTTACGCT
  CTCCATTTTAGATGAGAATGATGACTTCACCATTGATTCACAAACTGGTGTCATCCGACCAAATATTTCA
  TTTGATAGAGAAAAACAAGAATCTTACACTTTCTATGTAAAGGCTGAGGATGGTGGTAGAGTATCACGTT
  CTTCAAGTGCCAAAGTAACCATAAATGTGGTTGATGTCAATGACAACAAACCAGTTTTCATTGTCCCTCC
  TTCCAACTGTTCTTATGAATTGGTTCTACCGTCCACTAATCCAGGCACAGTGGTCTTTCAGGTAATTGCT
  GTTGACAATGACACTGGCATGAATGCAGAGGTTCGTTACAGCATTGTAGGAGGAAACACAAGAGATCTGT
  TTGCAATCGACCAAGAAACAGGCAACATAACATTGATGGAGAAATGTGATGTTACAGACCTTGGTTTACA
  CAGAGTGTTGGTCAAAGCTAATGACTTAGGACAGCCTGATTCTCTCTTCAGTGTTGTAATTGTCAATCTG
  TTCGTGAATGAGTCGGTGACCAATGCTACACTGATTAATGAACTGGTGCGCAAAAGCACTGAAGCACCAG
  TGACCCCAAATACTGAGATAGCTGATGTATCCTCACCAACTAGTGACTATGTCAAGATCCTGGTTGCAGC
  TGTTGCTGGCACCATAACTGTCGTTGTAGTTATTTTCATCACTGCTGTAGTAAGATGTCGCCAGGCACCA
  CACCTTAAGGCTGCTCAGAAAAACAAGCAGAATTCTGAATGGGCTACCCCAAACCCAGAAAACAGGCAGA
  TGATAATGATGAAGAAAAAGAAAAAGAAGAAGAAGCATTCCCCTAAGAACTTGCTGCTTAATTTTGTCAC
  TATTGAAGAAACTAAGGCAGATGATGTTGACAGTGATGGAAACAGAGTCACACTAGACCTTCCTATTGAT
  CTAGAAGAGCAAACAATGGGAAAGTACAATTGGGTAACTACACCTACTACTTTCAAGCCCGACAGCCCTG
  ATTTGGCCCGACACTACAAATCTGCCTCTCCACAGCCTGCCTTCCAAATTCAGCCTGAAACTCCCCTGAA
  TTCGAAGCACCACATCATCCAAGAACTGCCTCTCGATAACACCTTTGTGGCCTGTGACTCTATCTCCAAG
  TGTTCCTCAAGCAGTTCAGATCCCTACAGCGTTTCTGACTGTGGCTATCCAGTGACGACCTTCGAGGTAC
  CTGTGTCCGTACACACCAGACCGCCAATGAAGGAGGTTGTGCGATCTTGCACCCCCATGAAAGAGTCTAC
  AACTATGGAGATCTGGATTCATCCCCAACCACAGCGGAAATCTGAAGGGAAAGTGGCAGGAAAGACTGTG
  CTTACTTCCTCTTCCCCTTCTGCCATGACCCTTTCATACCTGGAC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC230638 representing NM_001168361
  Red=Cloning site Green=Tags(s)
  
  MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTG
  DVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFP
  ATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDRE
  EKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGE
  NAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVND
  NVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET
  AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSA
  MDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSI
  IDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNIS
  FDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIA
  VDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNL
  FVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP
  HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPID
  LEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHIIQELPLDNTFVACDSISK
  CSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPPMKEVVRSCTPMKESTTMEIWIHPQPQRKSEGKVAGKTV
  LTSSSPSAMTLSYLD
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001168361
• ORF Size: 3195 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001168361.1, NP_001161833.1
• RefSeq ORF: 3198
• Locus ID: 27328
• Protein Families: Transmembrane
• MW: 118.1 kDa
• Gene Summary: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Disruption of this gene may be associated with developmental dyslexia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]