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DMXL2 (NM_001174117) Human Tagged ORF Clone
CAT#: RC230749
- TrueORF®
DMXL2 (Myc-DDK-tagged)-Human Dmx-like 2 (DMXL2), transcript variant 3
"NM_001174117" in other vectors (2)
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Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Symbol | DMXL2 |
| Synonyms | DFNA71; PEPNS; RC3 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC230749 representing NM_001174117
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCATCTGCATCAGGTCCTCACCGGAGCTGTCAACCCTGGAGACAACTGCTACTCCGTGGGCAGCGTCG GGGATGTCCCCTTCACGGCATATGGATCAGGCTGTGATATTGTTATTTTGGCAAATGACTTTGAATGTGT ACAGATCATTCCTGGTGCTAAGCATGGAAACATCCAAGTCAGCTGTGTGGAGTGTTCTAACCAACAAGGA AGAATTGCAGCTTCATATGGTAATGCTGTTTGTATATTTGAGCCCTTGGGCATAAATTCTCATAAAAGAA ATTGTCAACTCAAGTGCCAGTGGCTTAAAACTGGGCAGTTTTTTTTGAGTTCTGTGACATACAACTTAGC ATGGGATCCTCAAGATAATAGATTGTTGACAGCAACTGATTCTATTCAGTTGTGGGCTCCTCCAGGAGAT GATATTCTGGAAGAGGAGGAAGAAATTGATAATACAGTTCCTCCTGTTTTAAATGATTGGAAGTGTGTCT GGCAGTGCAAAACCTCAGTATCTGTACATTTGATGGAATGGTCTCCTGATGGTGAATATTTTGCTACTGC TGGAAAGGATGATTGTCTTTTGAAAGTGTGGTATCCTATGACTGGTTGGAAGTCTTCAATTATACCTCAG GATCATCATGAAGTAAAAAGGAGACAGTCCTCTACTCAATTTTCTTTTGTTTACTTGGCACATCCCCGAG CTGTGACAGGTTTTTCGTGGCGCAAAACTAGCAAGTATATGCCCAGGGGTTCTGTCTGTAATGTGTTGTT AACTTCATGTCATGATGGTGTGTGCCGGCTCTGGGCAGAAACTTTATTACCAGAAGACTGTCTTTTGGGT GAGCAGATTTGTGAGACTACCACTTCCAGCATTGCCAGCAGCCTTTCTCATGCTGGAAGACACAAAGACA GAATACAGCATGCTCTTGAGACAATACACCATTTGAAAAATTTAAGGAAAGGACAGAGGAGGTCATCTGT TCTTGTAACTCATGCTGAATTAATGCCCGACCAGACAGCAATGCATGAAGTTCAAAGACACATTTCCCAC CATGCAAATGCACTCTGTCATTTTCATATTGCAGCAAGCATCAACCCTGCCACAGATATTCCAAATGTCT TGGTTGGCACTGCATTTAATGTTGATGATGGAAATGGGGGCTTTGTAGTTCATTGGTTAAACAACAAGGA ATTTCATTTTACATCATCTACAGAAGTATTTATGCATCAATTACGAAAACTTTCTGATAAGCAGGTAGAT CATGAAAATGATGATGCAGATAGAGAAGATGAGGAACATTCACAGGAGGATAGAGAACGGGGTTTACATA TGAAATTAGACCATGATTTATCCCTGGATAGAGAATCTGAGGCAGGTACAGGATCATCAGAACATGAAGA TGGAGAAAGAGAAGGAAGTCCTAGAACTTACTCACGACTTAGTGTACCAATGCCACTGCCTACGGTTCTG CTTGATCGGAAGATTGAAACGCTGCTAACTGAATGGAATAAGAATCCTGATATGCTTTTTACAATACACC CTGTAGATGGTACCTTTCTAGTGTGGCATGTGAAGTATTTGGATGAATATAATCCTGGAATATTTAGACA AGTTCAGGTTTCTTTTTCTTCTCGGATTCCTGTTGCATTTCCCTCTGGTGATGCAAGCTCTCTTAGTAAA AATATCATGATGTATGCCTGTATAAATGCGACAAAAGATTCTCACCACACGCTGTTACACCAGGAGGGGA TGTCTGTAGGCAGTCCTCACGGATCACAGCCACACTCTAGATCCCACAGTACACATATGAACATCTTAGC TCCCACAGTAATGATGATCTCTAAACACATAGATGGTTCTTTAAATCAGTGGGCAGTCACTTTTGCTGAT AAGTCTGCCTTTACCACTGTTCTAACTGTATCTCACAAATTTAGATATTGCGGTCATCGATTTCACCTCA ATGACCTGGCATGTCATTCAGTTTTACCACTGTTATTGACATCCTCTCATCATAATGCTCTATTGACTCC TGAATTAGATTGTCAGTGGGACTCAGACAATAAATTAAGTAGATTAATGGACCCTGTAAAACATATAAAA GGTTCCTCGAAACAACCTCTTAGAAATGCAGCAACTCGTACATTTCATGACCCAAATGCAATCTACAGTG AACTTATTCTGTGGCGTGTAGACCCAATAGGACCTTTGTCATACACTGGAGGAGTATCAGAATTGGCTCG AATTAACTCTTTACATACCTCAGCGTTCTCTAATGTGGCTTGGCTTCCAACTCTCATTCCCAGTTACTGT CTAGGCACATACTGCAATTCTGCAAGTGCTTGCTTTGTTGCTTCTGATGGCAAAAATCTGAGACTCTATC AAGCTGTAGTGGATGCAAGGAAATTATTAGATGAATTGTCAGACCCAGAATCTTCAAAACTTATTGGAGA AGTGTTTAATATTGTGAGCCAACAGTCTACTGCTCGACCTGGCTGCATTATTGAACTCGACGCAATAACC AACCAATGTGGCTCAAATACACAGTTGCTTCATGTGTTTCAAGAAGACTTCATTATAGGATATAAACCAC ATAAGGAAGATATGGAGAAAAAGGAAACAGAAATATTTTTTCAGCCATCACAAGGATACCGCCCACCACC ATTTTCAGAAAAGTTCTTTCTAGTAGTAATTGAGAAGGACAGCAATAATAACTCTATTCTGCATATGTGG CACCTTCATCTTAAATCTGTACAAGCATGTTTAGGAAGAGATACATTAGATGAGTGTGGTTTGAGATACT TGTTAGCTATGCGCCTACACACATGCCTTTTGACATCGCTGCCTCCTTTATACCGAGTGCAGCTACTTCA TCAAGGTGTCTCTACATGCCATTTTGCCTGGGCTTTTCATTCTGAGGCTGAAGAAGAACTGATTAATATG ATTCCAGCAATTCAGAGAGGGGACCCCCAGTGGTCTGAATTAAGAGCTATGGGCATAGGATGGTGGGTGA GGAACATTAACACGCTTCGAAGATGCATTGAAAAGGTTGCCAAAGCTTCTTTTCAAAGGAACAATGATGC CTTAGATGCTGCACTATTCTACCTTTCAATGAAGAAGAAAGCAGTAGTGTGGGGTCTGTTTAGGTCACAG CATGATGAAAAAATGACAACATTTTTCAGCCACAACTTTAATGAAGATAGATGGCGAAAAGCTGCTTTGA AAAATGCTTTTTCCTTACTTGGAAAACAACGCTTTGAACAATCGGCTGCTTTTTTCTTGCTAGCTGGTTC ATTGAAAGATGCCATAGAGGTATGTCTTGAAAAAATGGAAGATATTCAGCTAGCCATGGTTATTGCCCGT TTATATGAATCTGAATTTGAGACTTCATCCACTTATATATCCATCCTAAATCAGAAGATTTTGGGTTGCC AAAAGGATGGCTCAGGATTCAGTTGCAAAAGATTACATCCTGATCCTTTCCTGCGTAGTCTTGCCTATTG GGTAATGAAAGATTACACCCGAGCCTTGGACACATTACTGGAACAAACACCAAAGGAGGATGATGAACAT CAAGTTATCATCAAGTCTTGTAACCCGGTGGCATTTAGTTTTTATAACTACCTTCGAACTCATCCTTTGC TCATTCGAAGAAATCTTGCCTCCCCTGAAGGAACTTTGGCAACCTTAGGTCTCAAAACTGAGAAGAACTT TGTTGATAAAATTAACCTCATAGAAAGAAAATTATTCTTTACCACTGCAAATGCTCATTTTAAAGTTGGA TGCCCTGTTTTAGCCTTGGAGGTACTCTCCAAAATTCCAAAAGTAACCAAAACATCTGCCTTATCTGCAA AAAAAGATCAGCCTGACTTCATTTCTCACAGGATGGATGATGTACCTTCACATTCAAAAGCTCTGAGTGA TGGCAATGGAAGTTCTGGCATTGAATGGTCAAATGTAACTTCATCACAGTATGACTGGAGTCAGCCAATA GTAAAAGTTGATGAGGAACCTCTTAATCTTGATTGGGGTGAAGATCACGACAGTGCCTTAGATGAAGAGG AAGACGATGCTGTTGGTTTAGTGATGAAAAGTACAGATGCCAGGGAAAAAGATAAACAATCAGATCAGAA GGCCTCAGACCCTAACATGTTATTAACACCTCAGGAAGAGGATGATCCTGAAGGTGATACTGAAGTTGAT GTGATTGCTGAACAACTAAAATTCAGAGCTTGTTTAAAGATCCTTATGACTGAATTAAGAACATTGGCTA CAGGTTATGAAGTAGATGGAGGAAAACTCAGATTTCAACTCTATAACTGGCTTGAAAAGGAAATTGCTGC CTTGCATGAGATATGTAATCATGAATCAGTTATTAAAGAGTATTCCAGTAAGACATATTCCAAAGTAGAG AGTGATCTGCTGGATCAGGAAGAAATGGTAGACAAACCAGATATTGGTTCCTATGAGCGCCATCAAATAG AAAGAAGAAGATTGCAGGCCAAACGAGAGCATGCAGAAAGACGAAAGTCGTGGTTGCAGAAAAACCAAGA TCTCCTGAGAGTATTTCTCAGCTACTGTAGCCTTCATGGGGCCCAAGGTGGTGGTTTGGCTTCAGTAAGG ATGGAACTCAAATTTTTGCTACAAGAATCACAACAGGAAACTACAGTAAAGCAGCTCCAGTCTCCACTAC CACTGCCTACCACCCTACCTCTGCTTTCAGCAAGTATTGCGTCAACAAAAACAGTCATAGCTAATCCTGT ATTGTACTTAAATAATCACATCCATGATATACTTTATACTATTGTTCAGATGAAAACACCACCTCATCCC AGTATTGAAGATGTGAAGGTGCACACACTTCATTCACTAGCAGCATCACTTTCTGCATCAATTTACCAAG CATTATGTGACAGTCATAGCTACAGTCAAACAGAAGGAAATCAGTTTACAGGAATGGCTTATCAAGGACT TCTTTTAAGTGATCGTAGAAGACTAAGGACAGAAAGCATTGAAGAACACGCAACACCAAATTCATCTCCT GCTCAATGGCCTGGTGTGAGCTCACTTATTAATCTTTTGAGTTCAGCCCAAGATGAAGACCAGCCAAAAC TGAACATTTTGCTATGTGAAGCTGTTGTTGCTGTTTACTTAAGTTTATTGATACATGCTCTTGCCACAAA TTCCTCCAGTGAATTATTTCGGCTTGCAGCCCACCCATTAAATAATCGAATGTGGGCTGCTGTTTTTGGA GGCGGTGTAAAACTTGTTGTGAAACCTCGAAGACAATCAGAAAATATTTCAGCACCTCCTGTCCTTTCTG AAGACATAGATAAACACCGTAGGAGATTTAACATGAGAATGCTCGTCCCTGGAAGGCCTGTAAAAGATGC TACCCCACCACCGGTGCCTGCAGAAAGACCATCTTACAAAGAAAAATTTATTCCTCCCGAACTTAGTATG TGGGATTATTTTGTTGCAAAGCCATTTCTTCCTTTGTCTGATAGTGGTGTTATATATGATTCTGATGAAA GCATTCATAGTGATGAAGAAGATGATGCCTTTTTTTCAGATACACAAATACAGGAGCACCAAGATCCAAA TTCCTATAGCTGGGCTCTTCTACATTTGACAATGGTTAAACTAGCACTTCACAATGTCAAGAATTTCTTT CCTATTGCTGGACTGGAATTCTCTGAGCTGCCTGTAACATCACCATTAGGTATTGCTGTGATTAAAAACT TGGAGAACTGGGAACAGATCTTGCAAGAGAAAATGGATCAGTTTGAAGGTCCACCCCCTAACTATATCAA CACATATCCAACTGACCTTTCAGTGGGAGCTGGACCAGCTATTCTTCGAAATAAAGCAATGCTAGAACCT GAAAATACCCCATTCAAGTCCCGGGATTCTTCTGCATTTCCAGTCAAACGACTTTGGCATTTCCTTGTTA AACAAGAGGTCCTTCAAGAGACATTTATTAGATATATTTTCACTAAGAAAAGAAAGCAGAGTGAGGTTGA AGCTGATCTGGGCTATCCAGGTGGAAAGGCGAAAGTCATCCATAAGGAATCTGATATGATCATGGCATTT TCTGTTAATAAGGCAAATTGTAATGAAATTGTTTTGGCTTCAACACATGATGTTCAAGAACTTGATGTTA CTTCTCTACTGGCCTGTCAGTCATACATATGGATCGGAGAAGAATATGACAGAGAATCCAAAAGTTCAGA TGATGTTGATTATCGTGGTTCCACTACAACTCTTTATCAACCCAGTGCAACATCCTATTCAGCAAGTCAG GTGCATCCACCTTCATCTCTGCCATGGCTGGGCACTGGACAGACTAGCACTGGAGCTAGTGTGCTTATGA AAAGGAATCTACATAATGTTAAGAGAATGACTTCACACCCAGTCCATCAATACTATCTTACAGGTGCTCA GGACGGCAGTGTACGAATGTTTGAATGGACGCGGCCTCAGCAACTTGTCTGCTTTCGTCAAGCTGGCAAT GCAAGAGTTACTAGATTATATTTTAATTCACAAGGCAACAAGTGTGGTGTTGCGGATGGAGAGGGTTTTC TGAGTATCTGGCAAGTTAACCAAACTGCATCAAATCCTAAACCTTATATGAGTTGGCAGTGCCACAGTAA AGCCACAAGTGACTTTGCATTTATTACCTCTTCAAGTCTAGTTGCCACATCTGGACACTCCAATGACAAT AGAAATGTTTGCCTCTGGGACACATTAATATCACCCGGAAACAGCCTCATTCATGGTTTCACGTGCCACG ATCATGGTGCCACGGTACTGCAGTATGCACCCAAACAGCAACTCCTAATCTCGGGGGGTAGGAAAGGACA CGTCTGCATTTTTGACATCAGGCAAAGGCAGCTCATTCACACGTTCCAGGCCCATGACTCAGCTATTAAG GCTCTGGCCTTGGATCCCTATGAGGAATATTTTACCACAGGTTCAGCAGAAGGTAACATAAAGGTTTGGA GATTGACAGGCCATGGCCTAATTCATTCATTTAAAAGTGAACATGCTAAGCAGTCCATATTTCGAAACAT TGGGGCTGGAGTCATGCAGATTGACATCATCCAGGGCAATCGGCTCTTCTCCTGTGGTGCAGATGGCACG CTGAAAACCAGGGTTTTGCCCAATGCTTTTAACATCCCTAACAGAATTCTTGACATTCTA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC230749 representing NM_001174117
Red=Cloning site Green=Tags(s) MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQVSCVECSNQQG RIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDSIQLWAPPGD DILEEEEEIDNTVPPVLNDWKCVWQCKTSVSVHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQ DHHEVKRRQSSTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLG EQICETTTSSIASSLSHAGRHKDRIQHALETIHHLKNLRKGQRRSSVLVTHAELMPDQTAMHEVQRHISH HANALCHFHIAASINPATDIPNVLVGTAFNVDDGNGGFVVHWLNNKEFHFTSSTEVFMHQLRKLSDKQVD HENDDADREDEEHSQEDRERGLHMKLDHDLSLDRESEAGTGSSEHEDGEREGSPRTYSRLSVPMPLPTVL LDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDASSLSK NIMMYACINATKDSHHTLLHQEGMSVGSPHGSQPHSRSHSTHMNILAPTVMMISKHIDGSLNQWAVTFAD KSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPELDCQWDSDNKLSRLMDPVKHIK GSSKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYC LGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAIT NQCGSNTQLLHVFQEDFIIGYKPHKEDMEKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNNSILHMW HLHLKSVQACLGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINM IPAIQRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQ HDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIAR LYESEFETSSTYISILNQKILGCQKDGSGFSCKRLHPDPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEH QVIIKSCNPVAFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNFVDKINLIERKLFFTTANAHFKVG CPVLALEVLSKIPKVTKTSALSAKKDQPDFISHRMDDVPSHSKALSDGNGSSGIEWSNVTSSQYDWSQPI VKVDEEPLNLDWGEDHDSALDEEEDDAVGLVMKSTDAREKDKQSDQKASDPNMLLTPQEEDDPEGDTEVD VIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSKTYSKVE SDLLDQEEMVDKPDIGSYERHQIERRRLQAKREHAERRKSWLQKNQDLLRVFLSYCSLHGAQGGGLASVR MELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHP SIEDVKVHTLHSLAASLSASIYQALCDSHSYSQTEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSSP AQWPGVSSLINLLSSAQDEDQPKLNILLCEAVVAVYLSLLIHALATNSSSELFRLAAHPLNNRMWAAVFG GGVKLVVKPRRQSENISAPPVLSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSM WDYFVAKPFLPLSDSGVIYDSDESIHSDEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALHNVKNFF PIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLSVGAGPAILRNKAMLEP ENTPFKSRDSSAFPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSEVEADLGYPGGKAKVIHKESDMIMAF SVNKANCNEIVLASTHDVQELDVTSLLACQSYIWIGEEYDRESKSSDDVDYRGSTTTLYQPSATSYSASQ VHPPSSLPWLGTGQTSTGASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGN ARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDN RNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIK ALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCGADGT LKTRVLPNAFNIPNRILDIL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001174117 |
| ORF Size | 7200 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001174117.1, NP_001167588.1 |
| RefSeq ORF | 7203 |
| Locus ID | 23312 |
| MW | 270.6 kDa |
| Gene Summary | This gene encodes a protein with 12 WD domains. Proteins with WD domains are involved in many functions including participation in signal transduction pathways. Participation of the encoded protein in regulation of the Notch signaling pathway has been demonstrated in vitro using several human cell lines (PMID:20810660). A gene encoding a similar protein is located on chromosome 5. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] |
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