NCoR (NCOR1) (NM_001190440) Human Tagged ORF Clone

CAT#: RC230901

NCOR1 (Myc-DDK-tagged)-Human nuclear receptor corepressor 1 (NCOR1), transcript variant 3

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: NCOR1
• Synonyms: hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC230901 representing NM_001190440
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTCAAGTTCAGGTTATCCTCCCAACCAAGGAGCATTCAGCACAGAACAAAGTCGTTATCCTCCTCACT
  CTGTCCAGTATACATTTCCCAACACCCGCCACCAGCAGGAGTTCGCAGTCCCTGATTATCGTTCCTCTCA
  TCTTGAAGTGAGTCAGGCATCACAGCTTTTGCAGCAACAGCAGCAGCAACAGCTTCGAAGGCGACCTTCC
  TTGCTTTCAGAATTTCACCCAGGTTCTGACAGGCCTCAAGAAAGGAGAACTAGTTATGAACCGTTTCATC
  CAGGCCCATCCCCAGTGGATCATGATTCACTGGAATCGAAGCGACCACGTCTGGAACAGGTTTCTGATTC
  TCATTTTCAGCGTGTCAGTGCTGCGGTTTTGCCTTTAGTGCACCCGCTGCCAGAAGGGCTGAGGGCTTCT
  GCAGATGCTAAGAAGGATCCAGCATTCGGAGGCAAACATGAAGCTCCATCCTCTCCAATTTCGGGGCAAC
  CATGTGGAGATGATCAAAATGCTTCACCTTCAAAACTCTCAAAGGAAGAGTTAATACAGAGTATGGATCG
  TGTAGATCGAGAAATTGCAAAAGTAGAACAGCAGATCCTTAAACTGAAAAAGAAACAACAACAGCTTGAA
  GAAGAGGCAGCTAAACCTCCTGAGCCTGAGAAGCCCGTGTCCCCTCCTCCTGTGGAGCAGAAACACCGCA
  GTATTGTCCAAATTATTTATGATGAGAATCGGAAGAAAGCAGAAGAAGCTCATAAAATTTTTGAAGGTCT
  TGGCCCAAAAGTTGAACTGCCACTGTATAACCAGCCATCAGATACCAAGGTGTACCATGAGAACATCAAG
  ACAAACCAGGTGATGAGGAAAAAACTCATTTTATTTTTTAAAAGAAGAAATCATGCAAGAAAACAAAGGG
  AACAAAAAATCTGCCAGCGTTATGATCAGCTCATGGAGGCATGGGAGAAAAAAGTGGACAGAATAGAAAA
  TAATCCTCGGAGGAAAGCTAAAGAAAGCAAAACAAGGGAATACTATGAAAAGCAGTTTCCAGAAATTCGA
  AAACAAAGAGAACAGCAAGAAAGATTTCAGCGAGTTGGGCAGAGGGGAGCTGGTCTTTCAGCCACCATTG
  CTAGGAGTGAGCATGAGATTTCTGAAATTATTGATGGGCTCTCTGAGCAGGAGAATAATGAGAAACAAAT
  GCGGCAGCTCTCTGTGATTCCACCTATGATGTTTGATGCAGAACAAAGACGAGTCAAGTTCATTAACATG
  AATGGGCTTATGGAGGACCCTATGAAAGTGTATAAAGATAGGCAGTTTATGAATGTTTGGACTGACCATG
  AAAAGGAGATCTTTAAGGACAAGTTTATCCAGCATCCAAAAAACTTTGGACTAATTGCATCATACTTGGA
  GAGGAAGAGTGTTCCTGATTGTGTTTTGTATTACTATTTAACCAAGAAAAATGAGAATTATAAAGCCCTC
  GTCAGAAGGAATTATGGGAAACGCAGAGGCAGAAACCAGCAAATTGCTCGACCCTCGCAAGAAGAAAAAG
  TAGAAGAAAAAGAAGAGGATAAAGCAGAAAAAACAGAAAAAAAAGAAGAAGAAAAGAAAGATGAAGAGGA
  AAAAGATGAAAAAGAAGACTCCAAAGAAAATACCAAGGAAAAGGACAAGATAGATGGTACAGCAGAAGAA
  ACTGAGGAAAGAGAGCAAGCCACACCCCGGGGGCGAAAGACTGCCAACAGTCAGGGCCGCCGTAAGGGCC
  GGATCACCAGGTCCATGACAAACGAAGCTGCAGCTGCCAGTGCTGCAGCCGCAGCGGCTACTGAAGAGCC
  CCCACCACCTCTGCCACCGCCACCAGAACCCATTTCTACAGAGCCTGTGGAGACCTCTCGATGGACAGAA
  GAAGAAATGGAAGTTGCTAAAAAAGGTCTAGTAGAACATGGTCGTAACTGGGCAGCAATTGCTAAAATGG
  TGGGAACGAAAAGTGAAGCTCAATGTAAAAACTTCTATTTTAACTATAAAAGGCGACACAATCTTGACAA
  CCTCTTACAGCAGCATAAACAGAAAACTTCACGAAAACCTCGTGAAGAGCGAGATGTGTCTCAATGTGAA
  AGTGTCGCTTCCACTGTTTCTGCTCAGGAGGATGAAGATATTGAAGCCTCCAATGAAGAAGAAAATCCAG
  AAGACAGCGAAGGTGCAGAAAATAGTTCTGATACAGAAAGTGCTCCTTCTCCTTCACCAGTTGAAGCTGT
  CAAGCCCAGCGAGGACAGTCCTGAAAATGCTACTTCTCGAGGAAACACAGAACCTGCGGTTGAGCTTGAG
  CCCACCACGGAAACTGCACCCAGTACATCTCCCTCCTTAGCAGTTCCAAGTACAAAACCAGCTGAAGATG
  AAAGTGTGGAGACCCAGGTGAATGACAGCATCAGTGCTGAGACAGCAGAGCAGATGGATGTAGATCAGCA
  GGAGCACAGTGCTGAAGAGGGTTCTGTTTGTGATCCCCCACCCGCTACCAAAGCTGACTCTGTGGACGTT
  GAAGTGAGGGTGCCAGAAAACCATGCATCTAAAGTTGAAGGTGATAATACCAAAGAAAGAGACTTGGATA
  GAGCCAGTGAGAAGGTGGAACCTAGAGATGAAGATTTGGTGGTAGCTCAGCAAATAAATGCCCAAAGGCC
  CGAGCCCCAGTCAGACAATGATTCCAGTGCCACGTGCAGCGCTGATGAGGATGTGGATGGAGAGCCAGAG
  AGGCAGAGAATGTTTCCTATGGACTCAAAGCCTTCACTGTTAAACCCCACTGGATCTATACTCGTCTCAT
  CTCCGTTAAAACCAAATCCACTGGATCTGCCACAGCTTCAGCATCGAGCTGCTGTTATCCCACCAATGGT
  ATCCTGCACCCCATGTAACATACCAATTGGAACCCCAGTGAGCGGCTATGCTCTCTACCAGCGACACATT
  AAAGCAATGCATGAGTCAGCACTCCTGGAGGAGCAGCGGCAGAGACAAGAACAGATAGATTTGGAATGTA
  GAAGTTCTACAAGTCCATGTGGCACATCCAAGAGTCCAAACAGAGAGTGGGAAGTCCTTCAGCCTGCTCC
  ACATCAAGTGATAACTAATCTCCCTGAAGGCGTTCGGCTTCCGACAACTCGACCAACCAGGCCACCGCCC
  CCTCTCATCCCGTCATCCAAAACCACAGTGGCTTCAGAAAAACCATCTTTTATAATGGGAGGCTCCATCT
  CACAGGGAACACCAGGCACTTATTTGACTTCTCATAATCAGGCTTCCTACACTCAAGAAACACCCAAGCC
  GTCAGTGGGATCTATCTCTCTTGGACTGCCACGGCAACAGGAATCTGCCAAATCAGCTACTTTGCCCTAC
  ATCAAGCAGGAAGAATTTTCTCCCCGAAGCCAAAACTCACAACCTGAGGGTCTGTTGGTCAGGGCCCAAC
  ATGAAGGTGTAGTCAGAGGTACCGCAGGAGCCATACAAGAAGGAAGTATAACTCGGGGAACTCCAACCAG
  CAAAATTTCAGTGGAGAGCATTCCATCCCTACGGGGCTCTATCACTCAGGGCACCCCGGCTCTGCCCCAG
  ACTGGCATACCAACAGAGGCTTTGGTGAAGGGGTCCATTTCGAGAATGCCCATTGAAGACAGCAGTCCTG
  AGAAAGGCAGAGAGGAAGCTGCATCCAAAGGCCATGTTATTTATGAAGGCAAAAGTGGACATATCTTGTC
  ATATGATAATATTAAGAATGCCCGAGAAGGGACTAGGAGTCCAAGAACAGCTCATGAAATCAGTTTAAAG
  AGAAGCTATGAATCAGTGGAAGGAAATATAAAGCAAGGGATGTCAATGAGGGAGTCTCCTGTATCAGCAC
  CGTTAGAGGGGCTGATATGCCGAGCATTACCCAGGGGGAGTCCTCATTCTGACCTCAAAGAAAGGACTGT
  ATTGTCTGGCTCCATAATGCAGGGGACACCAAGAGCAACAACTGAAAGCTTTGAAGATGGCCTTAAATAT
  CCCAAACAAATTAAAAGGGAAAGTCCTCCCATACGAGCATTTGAAGGTGCCATTACCAAAGGAAAACCAT
  ATGATGGCATCACCACCATCAAAGAAATGGGGCGTTCCATTCATGAGATTCCAAGGCAAGATATTTTAAC
  TCAGGAAAGTCGGAAAACTCCAGAAGTGGTCCAGAGCACACGGCCGATAATTGAGGGTTCCATTTCCCAG
  GGCACACCAATAAAGTTTGACAACAACTCAGGTCAATCTGCCATCAAACACAATGTCAAATCCTTAATCA
  CGGGGCCTAGCAAACTATCCCGTGGAATGCCTCCGCTGGAAATTGTGCCAGAGAACATAAAAGTGGTAGA
  ACGGGGAAAATATGAGGATGTGAAAGCAGGCGAGACCGTGCGTTCCCGGCACACGTCAGTGGTAAGCTCT
  GGCCCCTCCGTTCTTAGGTCCACACTGCATGAAGCTCCCAAAGCACAACTGAGCCCTGGGATTTATGATG
  ACACCAGTGCACGGAGGACCCCTGTGAGTTATCAAAACACCATGTCCAGAGGCTCACCCATGATGAACAG
  AACTTCTGATGTTACAATTTCTTCTAACAAGTCTACCAATCATGAAAGGAAATCGACACTGACCCCTACC
  CAGAGGGAAAGTATCCCAGCGAAGTCTCCAGTGCCTGGGGTGGACCCTGTCGTGAGCCACAGTCCGTTTG
  ATCCCCATCACAGAGGCAGCACTGCAGGCGAGGTTTATCGGAGCCACCTGCCCACGCACTTGGATCCAGC
  CATGCCTTTTCACAGGGCTTTGGATCCTGCAGCGGCTGCTTACCTGTTTCAGAGACAGCTTTCACCAACT
  CCAGGTTACCCAAGTCAGTATCAGCTTTACGCAATGGAGAACACAAGACAGACAATCTTAAATGATTACA
  TTACCTCACAACAGATGCAAGTGAACTTGCGTCCAGATGTGGCCAGAGGACTCTCCCCAAGAGAGCAGCC
  ACTGGGTCTCCCATACCCAGCAACGAGAGGAATCATTGACCTGACCAATATGCCTCCAACAATTTTAGTG
  CCTCATCCAGGGGGAACAAGCACTCCTCCCATGGACAGAATCACTTATATTCCTGGTACACAGATTACTT
  TCCCTCCCAGGCCGTACAACTCTGCTTCCATGTCTCCAGGACACCCAACACACCTTGCAGCTGCTGCAAG
  TGCTGAGAGGGAACGGGAACGGGAGCGGGAGAAGGAGCGGGAGCGGGAACGGATTGCTGCAGCTTCCTCC
  GACCTCTACCTGCGGCCAGGCTCAGAACAGCCTGGCCGACCTGGCAGTCATGGATATGTTCGCTCCCCTT
  CCCCTTCAGTAAGAACTCAGGAGACCATGTTGCAACAGAGACCCAGTGTTTTCCAAGGAACCAATGGAAC
  CAGTGTAATCACACCTTTGGATCCAACTGCTCAGCTACGAATCATGCCACTGCCTGCTGGGGGCCCTTCA
  ATAAGCCAAGGCCTGCCAGCCTCCCGTTACAACACTGCTGCGGATGCCCTGGCTGCTCTTGTGGATGCTG
  CAGCTTCTGCACCCCAGATGGATGTGTCCAAAACAAAAGAGATATCTTCTCACAGGTATGAAACACCTAG
  CGATGCTATTGAGGTGATAAGTCCTGCCAGCTCACCTGCGCCACCCCAGGAGAAACTGCAGACCTATCAG
  CCAGAGGTTGTTAAGGCAAATCAAGCGGAAAATGATCCTACCAGACAATATGAAGGACCATTACATCACT
  ATCGACCACAGCAGGAATCACCATCTCCCCAACAACAGCTGCCCCCTTCTTCACAGGCAGAGGGAATGGG
  GCAAGTGCCCAGGACCCATCGGCTGATCACACTTGCTGATCACATCTGTCAAATTATCACACAAGATTTT
  GCTAGAAATCAAGTTTCCTCGCAGACTCCCCAGCAGCCTCCTACTTCTACATTCCAGAACTCACCTTCTG
  CTTTGGTATCTACACCTGTGAGGACTAAAACATCAAACCGTTACAGCCCAGAATCCCAGGCTCAGTCTGT
  CCATCATCAAAGACCAGGTTCAAGGGTCTCTCCAGAAAATCTTGTGGACAAATCCAGGGGAAGTAGGCCT
  GGAAAATCCCCAGAGAGGAGTCACGTCTCTTCGGAGCCCTACGAGCCCATCTCCCCACCCCAGGTTCCGG
  TTGTGCATGAGAAACAGGACAGCTTGCTGCTCTTGTCTCAGAGGGGCGCAGAGCCTGCAGAGCAGAGGAA
  TGATGCCCGCTCACCAGGGAGTATAAGCTACTTGCCTTCATTCTTCACCAAGCTTGAAAATACATCACCC
  ATGGTTAAATCAAAGAAGCAGGAGATTTTTCGTAAGTTGAACTCCTCTGGTGGAGGTGACTCTGATATGG
  CAGCTGCTCAGCCAGGAACTGAGATCTTTAATCTGCCAGCAGTTACTACGTCAGGCTCAGTTAGCTCTAG
  AGGCCATTCTTTTGCTGATCCTGCCAGTAATCTTGGGCTGGAAGACATTATCAGGAAGGCTCTCATGGGA
  AGCTTTGATGACAAAGTTGAGGATCATGGAGTTGTCATGTCCCAGCCTATGGGAGTAGTGCCTGGTACTG
  CCAACACCTCAGTTGTGACCAGTGGTGAGACACGAAGAGAGGAAGGGGACCCATCACCTCATTCAGGAGG
  AGTTTGCAAACCAAAGCTGATCAGCAAGTCAAACAGCAGGAAATCTAAGTCTCCTATACCTGGGCAAGGC
  TACTTAGGAACGGAACGGCCCTCTTCAGTCTCCTCTGTACATTCAGAAGGGGATTACCATAGGCAGACGC
  CAGGGTGGGCCTGGGAAGACAGGCCCTCTTCAACAGGCTCAACTCAGTTTCCTTATAACCCTCTGACTAT
  GCGGATGCTCAGCAGTACTCCACCAACACCGATTGCATGTGCTCCCTCTGCGGTGAACCAAGCAGCTCCT
  CACCAACAGAACAGGATCTGGGAGCGAGAGCCTGCCCCACTGCTCTCAGCACAGTACGAGACCCTGTCGG
  ATAGTGATGAC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC230901 representing NM_001190440
  Red=Cloning site Green=Tags(s)
  
  MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQQQQQLRRRPS
  LLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQRVSAAVLPLVHPLPEGLRAS
  ADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLE
  EEAAKPPEPEKPVSPPPVEQKHRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIK
  TNQVMRKKLILFFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIR
  KQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINM
  NGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKAL
  VRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEE
  TEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTE
  EEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCE
  SVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELE
  PTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDV
  EVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSADEDVDGEPE
  RQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCTPCNIPIGTPVSGYALYQRHI
  KAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPP
  PLIPSSKTTVASEKPSFIMGGSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPY
  IKQEEFSPRSQNSQPEGLLVRAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQ
  TGIPTEALVKGSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEISLK
  RSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRATTESFEDGLKY
  PKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQESRKTPEVVQSTRPIIEGSISQ
  GTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVSS
  GPSVLRSTLHEAPKAQLSPGIYDDTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPT
  QRESIPAKSPVPGVDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPT
  PGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPTILV
  PHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAEREREREREKERERERIAAASS
  DLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVITPLDPTAQLRIMPLPAGGPS
  ISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKEISSHRYETPSDAIEVISPASSPAPPQEKLQTYQ
  PEVVKANQAENDPTRQYEGPLHHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDF
  ARNQVSSQTPQQPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRP
  GKSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKLENTSP
  MVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASNLGLEDIIRKALMG
  SFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDPSPHSGGVCKPKLISKSNSRKSKSPIPGQG
  YLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQFPYNPLTMRMLSSTPPTPIACAPSAVNQAAP
  HQQNRIWEREPAPLLSAQYETLSDSDD
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001190440
• ORF Size: 7011 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001190440.1, NP_001177369.1
• RefSeq ORF: 7014
• Locus ID: 9611
• Protein Families: Druggable Genome
• MW: 259.1 kDa
• Gene Summary: This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20. [provided by RefSeq, Jun 2010]