FMRP (FMR1) (NM_001185075) Human Tagged ORF Clone
CAT#: RC231307L4
- LentiORF®
Lenti-ORF clone of FMR1 (mGFP-tagged)-Human fragile X mental retardation 1 (FMR1), transcript variant ISO6
"NM_001185075" in other vectors (3)
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | FMR1 |
Synonyms | FMRP; FRAXA; POF; POF1; POFX |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC231307).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_001185075 |
ORF Size | 1611 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001185075.1, NP_001172004.1 |
RefSeq ORF | 1614 bp |
Locus ID | 2332 |
Cytogenetics | Xq27.3 |
Protein Families | Druggable Genome |
MW | 61.5 kDa |
Gene Summary | 'The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC231307 | FMR1 (Myc-DDK-tagged)-Human fragile X mental retardation 1 (FMR1), transcript variant ISO6 |
USD 480.00 |
|
RG231307 | FMR1 (GFP-tagged) - Human fragile X mental retardation 1 (FMR1), transcript variant ISO6 |
USD 530.00 |
|
RC231307L3 | Lenti-ORF clone of FMR1 (Myc-DDK-tagged)-Human fragile X mental retardation 1 (FMR1), transcript variant ISO6 |
USD 680.00 |
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