Cullin 2 (CUL2) (NM_001198779) Human Tagged ORF Clone

CAT#: RC231403

CUL2 (Myc-DDK-tagged)-Human cullin 2 (CUL2), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: CUL2
• Synonyms: MGC131970
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC231403 representing NM_001198779
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGTGCCTGGCAAGGAATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTG
  ATGAAACATGGAACAAACTTTTGACGACAATAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAAC
  ATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCTGAACCCCTTGGAGAAAGACTT
  TATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAAG
  AACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTT
  ATATAGGTATCTCAACACCCAGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTAT
  GGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGAGAGCTAGCATTGGATATGTGGAGGAAATTGA
  TGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGATCGTGGTGGAGA
  AGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAA
  TTCCCCTTAAAGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAAC
  AAGAAGCTTCAAATTTATTACAAGAATCAAACTGCTCACAGTATATGGAAAAGGTTCTAGGTAGATTAAA
  AGATGAAGAAATTCGATGTCGAAAATACCTACATCCAAGTTCATATACTAAGGTGATTCATGAATGTCAA
  CAACGAATGGTAGCAGACCACTTACAGTTTTTACATGCAGAATGTCATAATATAATTCGACAAGAGAAAA
  AAAATGACATGGCAAATATGTACGTCTTACTCCGTGCTGTGTCCACTGGTTTACCTCATATGATTCAGGA
  GCTGCAAAACCACATCCATGATGAGGGCCTTCGAGCAACCAGCAACCTTACTCAGGAAAACATGCCAACA
  CTATTTGTGGAGTCAGTTTTGGAAGTGCATGGTAAATTTGTTCAGCTTATCAACACTGTTTTGAATGGTG
  ATCAGCATTTTATGAGTGCGTTGGATAAGGCCCTTACGTCAGTTGTAAATTACAGAGAACCTAAGTCTGT
  TTGCAAAGCACCTGAACTGCTTGCTAAGTACTGTGACAACTTACTGAAGAAGTCAGCGAAAGGGATGACA
  GAGAATGAAGTGGAAGACAGGCTCACGAGCTTCATCACAGTGTTCAAATACATTGATGACAAGGACGTCT
  TTCAAAAGTTCTACGCAAGAATGCTGGCAAAACGTTTAATTCATGGGTTATCCATGTCTATGGACTCTGA
  AGAAGCCATGATCAACAAATTAAAGCAAGCCTGTGGTTATGAGTTTACCAGCAAGCTACATCGGATGTAT
  ACAGATATGAGTGTCAGCGCTGATCTCAACAATAAGTTCAACAATTTTATCAAAAACCAAGACACAGTAA
  TAGATTTGGGAATTAGTTTTCAAATATATGTTCTACAGGCTGGTGCGTGGCCTCTTACTCAGGCTCCTTC
  ATCTACGTTTGCAATTCCCCAGGAATTAGAAAAAAGTGTACAGATGTTTGAATTATTTTATAGCCAACAT
  TTCAGTGGAAGGAAACTTACATGGTTACATTATCTGTGTACAGGTGAAGTTAAAATGAACTATTTGGGCA
  AACCATATGTAGCCATGGTTACAACATACCAAATGGCAGTTCTTCTTGCCTTTAACAACAGTGAAACTGT
  CAGTTATAAAGAGCTTCAGGACAGCACTCAGATGAATGAAAAGGAACTGACAAAAACAATCAAATCATTA
  CTTGATGTGAAAATGATTAACCATGATTCAGAAAAGGAAGATATTGATGCAGAATCTTCGTTTTCATTAA
  ATATGAACTTTAGCAGTAAAAGAACAAAATTTAAAATTACTACATCAATGCAGAAAGACACACCACAAGA
  AATGGAGCAGACTAGAAGTGCAGTTGATGAGGACCGGAAAATGTATCTCCAAGCTGCTATAGTTCGTATC
  ATGAAAGCACGAAAAGTGCTTCGGCACAATGCCCTTATTCAAGAGGTGATTAGCCAGTCAAGAGCTAGGT
  TTAATCCCAGTATCAGCATGATTAAGAAGTGTATTGAAGTTCTGATAGACAAACAATACATAGAACGCAG
  CCAGGCGTCGGCAGATGAATACAGCTACGTCGCG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC231403 representing NM_001198779
  Red=Cloning site Green=Tags(s)
  
  MVPGKEFQHYTCTMSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERL
  YTETKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGY
  GGVDMNEPLMEIGELALDMWRKLMVEPLQAILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHVEQYKKK
  FPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKVLGRLKDEEIRCRKYLHPSSYTKVIHECQ
  QRMVADHLQFLHAECHNIIRQEKKNDMANMYVLLRAVSTGLPHMIQELQNHIHDEGLRATSNLTQENMPT
  LFVESVLEVHGKFVQLINTVLNGDQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMT
  ENEVEDRLTSFITVFKYIDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMY
  TDMSVSADLNNKFNNFIKNQDTVIDLGISFQIYVLQAGAWPLTQAPSSTFAIPQELEKSVQMFELFYSQH
  FSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAVLLAFNNSETVSYKELQDSTQMNEKELTKTIKSL
  LDVKMINHDSEKEDIDAESSFSLNMNFSSKRTKFKITTSMQKDTPQEMEQTRSAVDEDRKMYLQAAIVRI
  MKARKVLRHNALIQEVISQSRARFNPSISMIKKCIEVLIDKQYIERSQASADEYSYVA
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001198779
• ORF Size: 2274 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001198779.1, NP_001185708.1
• RefSeq ORF: 2277
• Locus ID: 8453
• Protein Families: Druggable Genome
• Protein Pathways: Pathways in cancer, Renal cell carcinoma, Ubiquitin mediated proteolysis
• MW: 89 kDa