NKD2 (NM_001271082) Human Tagged ORF Clone

CAT#: RC232453

NKD2 (Myc-DDK tagged) - Homo sapiens naked cuticle homolog 2 (Drosophila) (NKD2), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: NKD2
• Synonyms: Naked2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC232453 representing NM_001271082
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGGAAACTGCAGTCGAAGCACGCCGCCGCCGCCCGCAAGCGGAGAGAGAGCCCGGAAGGGGACAGCT
  TCGTGGCGTCCGCGTACGCGAGCGGCCGCAAAGGCGCGGAGGAAGCGGAGCGGCGCGCGCGGGACAAGCA
  GGAGCTGCCCAATGGGGACCCCAAGGAGGGGCCTTTCCGGGAGGACCAGTGTCCCCTACAGGTGGCACTC
  CCCGCTGAGAAAGCTGAGGGCCGCGAGCACCCGGGACAACTCCTCAGCGCAGATGACGGAGAGAGGGCAG
  CAAACCGCGAGGGCCCGCGAGGACCGGGCGGGCAGCGCCTCAACATTGACGCACTCCAGTGCGATGTCTC
  GGTGGAGGAGGACGACCGCCAGGAGTGGACGTTCACGCTCTATGACTTTGACAACTGCGGGAAGGTCACC
  AGGGAGGACATGTCCAGCCTCATGCACACCATCTATGAGGTCGTGGATGCCTCGGTCAACCACTCCTCGG
  GCAGCAGCAAGACCCTCCGTGTGAAGCTAACCGTCAGCCCTGAGCCCTCCAGCAAGAGGAAGGAGGGTCC
  TCCTGCTGGCCAGGACCGGGAGCCCACCCGTTGCAGGATGGAGGGTGAACTGGCAGAGGAGCCAAGGGTG
  GCTGACAGGAGGTTGTCTGCACACGTCAGGAGGCCCAGTACTGACCCCCAGCCCTGCTCGGAGCGGGGGC
  CCTACTGCGTGGACGAGAACACGGAGCGCAGAAACCACTACCTGGACCTCGCCGGGATTGAGAACTACAC
  GTCCAGATTCGGCCCTGGGTCTCAGCTGTGCGAGAAGAGAAGCTCCGCTCCCAGGACACACAGTGGGGAC
  AAGGCTAGAGGAGTCGGCCTTTGCAGGGAGCTGTGGAGCCAGGCAGGTCACCCACAGTGGCCAGGCCCCT
  TCCCTTCAGGGCTGGTGGCCGTC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC232453 representing NM_001271082
  Red=Cloning site Green=Tags(s)
  
  MGKLQSKHAAAARKRRESPEGDSFVASAYASGRKGAEEAERRARDKQELPNGDPKEGPFREDQCPLQVAL
  PAEKAEGREHPGQLLSADDGERAANREGPRGPGGQRLNIDALQCDVSVEEDDRQEWTFTLYDFDNCGKVT
  REDMSSLMHTIYEVVDASVNHSSGSSKTLRVKLTVSPEPSSKRKEGPPAGQDREPTRCRMEGELAEEPRV
  ADRRLSAHVRRPSTDPQPCSERGPYCVDENTERRNHYLDLAGIENYTSRFGPGSQLCEKRSSAPRTHSGD
  KARGVGLCRELWSQAGHPQWPGPFPSGLVAV
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001271082
• ORF Size: 933 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001271082.1, NP_001258011.1
• RefSeq Size: 2070
• RefSeq ORF: 936
• Locus ID: 85409
• Protein Families: Druggable Genome
• Protein Pathways: Wnt signaling pathway
• MW: 34.8 kDa
• Gene Summary: This gene encodes a member of a family of proteins that function as negative regulators of Wnt receptor signaling through interaction with Dishevelled family members. The encoded protein participates in the delivery of transforming growth factor alpha-containing vesicles to the cell membrane. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]