B7 H6 (NCR3LG1) (NM_001202439) Human Tagged ORF Clone

CAT#: RC232774

NCR3LG1 (Myc-DDK tagged) - Homo sapiens natural killer cell cytotoxicity receptor 3 ligand 1 (NCR3LG1)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: NCR3LG1
• Synonyms: B7-H6; B7H6; DKFZp686O24166
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC232774 representing NM_001202439
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACGTGGAGGGCTGCCGCCTCCACGTGCGCGGCGCTCCTGATTCTGCTGTGGGCGCTGACGACCGAAG
  GTGATCTGAAAGTAGAGATGATGGCAGGGGGGACTCAGATCACACCCCTGAATGACAATGTCACCATATT
  CTGCAATATCTTTTATTCCCAACCCCTCAACATCACGTCTATGGGTATCACCTGGTTTTGGAAGAGTCTG
  ACGTTTGACAAAGAAGTCAAAGTCTTTGAATTTTTTGGAGATCACCAAGAGGCATTCCGACCTGGAGCCA
  TTGTGTCTCCATGGAGGCTGAAGAGTGGGGACGCCTCACTGCGGCTGCCTGGAATCCAGCTGGAGGAAGC
  AGGAGAGTACCGATGTGAGGTGGTGGTCACCCCTCTGAAGGCACAGGGAACAGTCCAGCTTGAAGTTGTG
  GCTTCCCCAGCCAGCAGATTGTTGCTGGATCAAGTGGGCATGAAAGAGAATGAAGACAAATATATGTGTG
  AGTCAAGTGGGTTCTACCCAGAGGCTATTAATATAACATGGGAGAAGCAGACCCAGAAGTTTCCCCATCC
  CATAGAGATTTCTGAGGATGTCATCACTGGTCCCACCATCAAGAATATGGATGGCACATTTAATGTCACT
  AGCTGCTTGAAGCTGAACTCCTCTCAGGAAGACCCTGGGACTGTCTACCAGTGTGTGGTACGGCATGCGT
  CCTTGCATACCCCCTTGAGGAGCAACTTTACCCTGACTGCTGCTCGGCACAGTCTTTCTGAAACTGAGAA
  GACAGATAATTTTTCCATTCATTGGTGGCCTATTTCATTCATTGGTGTTGGACTGGTTTTATTAATTGTT
  TTGATTCCTTGGAAAAAGATATGTAACAAATCATCTTCAGCCTATACTCCTCTCAAGTGCATTCTGAAAC
  ACTGGAACTCCTTTGACACTCAGACTCTGAAGAAAGAGCACCTCATATTCTTTTGCACTCGGGCATGGCC
  GTCTTACCAGCTGCAGGATGGGGAGGCTTGGCCTCCTGAGGGAAGTGTTAATATTAATACTATTCAACAA
  CTAGATGTTTTCTGCAGACAGGAGGGCAAATGGTCCGAGGTTCCTTATGTGCAAGCCTTCTTTGCCTTGC
  GAGACAACCCAGATCTTTGTCAGTGTTGTAGAATTGACCCTGCTCTCCTAACAGTTACATCAGGCAAGTC
  CATAGATGATAATTCCACAAAGTCTGAGAAACAAACCCCTAGGGAACACTCGGATGCAGTTCCGGATGCC
  CCAATCCTTCCTGTCTCCCCTATCTGGGAACCTCCTCCAGCCACAACATCAACAACTCCAGTTCTATCCT
  CCCAACCCCCAACTTTACTGTTACCCCTACAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC232774 representing NM_001202439
  Red=Cloning site Green=Tags(s)
  
  MTWRAAASTCAALLILLWALTTEGDLKVEMMAGGTQITPLNDNVTIFCNIFYSQPLNITSMGITWFWKSL
  TFDKEVKVFEFFGDHQEAFRPGAIVSPWRLKSGDASLRLPGIQLEEAGEYRCEVVVTPLKAQGTVQLEVV
  ASPASRLLLDQVGMKENEDKYMCESSGFYPEAINITWEKQTQKFPHPIEISEDVITGPTIKNMDGTFNVT
  SCLKLNSSQEDPGTVYQCVVRHASLHTPLRSNFTLTAARHSLSETEKTDNFSIHWWPISFIGVGLVLLIV
  LIPWKKICNKSSSAYTPLKCILKHWNSFDTQTLKKEHLIFFCTRAWPSYQLQDGEAWPPEGSVNINTIQQ
  LDVFCRQEGKWSEVPYVQAFFALRDNPDLCQCCRIDPALLTVTSGKSIDDNSTKSEKQTPREHSDAVPDA
  PILPVSPIWEPPPATTSTTPVLSSQPPTLLLPLQ
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001202439
• ORF Size: 1362 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001202439.1, NM_001202439.2, NP_001189368.1
• RefSeq Size: 6382
• RefSeq ORF: 1365
• Locus ID: 374383
• Protein Families: Transmembrane
• MW: 51.3 kDa
• Gene Summary: B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]). [supplied by OMIM, Jan 2011]