ATRIP (NM_001271022) Human Tagged ORF Clone

CAT#: RC233065

ATRIP (Myc-DDK tagged) - Homo sapiens ATR interacting protein (ATRIP), transcript variant 3

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: ATRIP
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC233065 representing NM_001271022
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAAGTAATGGAAGAAGAAGTTCTCATTAAGAATGGAGAAATTAAAATTTTGCGAGACTCACTACATC
  AGACGGAATCCGTTCTAGAGGAACAGAGAAGATCACATTTTCTTCTTGAGCAAGAGAAAACCCAAGCACT
  CAGTGACAAGGAAAAGGAATTCTCCAAAAAGCTCCAATCATTGCAGTCTGAACTCCAGTTTAAAGATGCA
  GAGATGAATGAATTAAGGACAAAGCTCCAGACCAGTGAACGAGCAAATAAACTGGCTGCTCCCTCTGTTT
  CCCATGTCAGTCCTAGGAAAAACCCTTCTGTGGTTATAAAGCCAGAAGCATGTTCTCCACAATTTGGAAA
  AACATCTTTTCCTACAAAGGAGTCTTTTAGTGCTAACATGTCCCTTCCCCACCCCTGCCAGACGGAGTCA
  GGATACAAGCCTCTGGTGGGCAGAGAGGATAGTAAGCCCCACAGTCTGAGAGGTGACTCCATAAAACAAG
  AAGAGGCCCAGAAAAGCTTTGTTGACAGCTGGAGACAGAGATCAAACACTCAAGGTTCCATTTTGATAAA
  CCTGCTCCTGAAGCAGCCTTTGATCCCAGGGTCATCCCTAAGCCTTTGCCACCTCCTGAGTAGTAGTTCT
  GAGTCTCCTGCTGGCACCCCCCTGCAGCCACCAGGGTTTGGCAGTACCTTGGCTGGAATGTCAGGCCTCA
  GGACCACAGGTTCTTATGATGGGTCATTTTCCCTCTCAGCCCTGAGAGAAGCACAGAACCTGGCATTCAC
  TGGACTGAATCTGGTTGCCCGGAATGAGTGCTCACGTGATGGAGACCCAGCAGAGGGAGGCAGAAGGGCC
  TTCCCACTCTGCCAGCTTCCTGGAGCCGTGCATTTCCTCCCCCTTGTACAGTTCTTCATCGGCTTACACT
  GCCAGGCCCTGCAGGACTTGGCAGCTGCTAAGAGAAGCGGAGCACCTGGGGACTCACCGACACATTCCTC
  CTGCGTGAGCTCTGGGGTAGAGACCAACCCTGAGGACTCAGTGTGCATCCTGGAAGGCTTCTCTGTGACT
  GCACTTAGCATTCTTCAGCACCTGGTGTGCCACAGCGGAGCAGTCGTCTCCCTATTACTGTCAGGAGTGG
  GGGCAGATTCTGCTGCTGGGGAAGGAAACAGGAGCCTGGTTCACAGGCTTAGTGATGGAGATATGACCTC
  AGCCCTAAGGGGGGTTGCTGATGACCAAGGACAGCACCCACTGTTGAAGATGCTTCTTCACCTGTTGGCT
  TTCTCTTCTGCAGCAACAGGTCACCTTCAAGCCAGTGTCCTGACCCAGTGCCTTAAGGTTTTGGTGAAAT
  TAGCCGAAAACACTTCCTGTGATTTCTTGCCCAGGTTCCAGTGTGTGTTCCAAGTGCTGCCAAAGTGCCT
  CAGCCCAGAGACACCCCTGCCTAGCGTGCTGCTGGCTGTTGAGCTCCTCTCCCTGCTGGCGGACCACGAC
  CAGCTGGCACCTCAGCTCTGTTCCCACTCAGAAGGCTGCCTCCTGCTGCTGCTGTACATGTACATCACAT
  CACGGCCTGACAGAGTGGCCTTGGAGACACAATGGCTCCAGCTGGAACAAGAGGTGGTGTGGCTCCTGGC
  TAAGCTTGGTGTGCAGAGCCCCTTGCCCCCAGTCACTGGCTCCAACTGCCAGTGTAATGTGGAGGTGGTC
  AGAGCGCTCACGGTGATGTTGCACAGACAGTGGCTGACAGTGCGGAGGGCAGGGGGACCCCCAAGGACCG
  ACCAGCAGAGGCGGACAGTGCGCTGTCTGCGGGACACGGTGCTGCTGCTGCACGGCCTATCGCAGAAGGA
  CAAGCTCTTCATGATGCACTGCGTGGAGGTCCTGCATCAGTTTGACCAGGTGATGCCGGGGGTCAGCATG
  CTCATCCGAGGGCTTCCTGATGTGACGGACTGTGAAGAGGCAGCCCTGGATGACCTCTGTGCCGCGGAAA
  CCGATGTGGAAGACCCCGAGGTGGAGTGTGGC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC233065 representing NM_001271022
  Red=Cloning site Green=Tags(s)
  
  MKVMEEEVLIKNGEIKILRDSLHQTESVLEEQRRSHFLLEQEKTQALSDKEKEFSKKLQSLQSELQFKDA
  EMNELRTKLQTSERANKLAAPSVSHVSPRKNPSVVIKPEACSPQFGKTSFPTKESFSANMSLPHPCQTES
  GYKPLVGREDSKPHSLRGDSIKQEEAQKSFVDSWRQRSNTQGSILINLLLKQPLIPGSSLSLCHLLSSSS
  ESPAGTPLQPPGFGSTLAGMSGLRTTGSYDGSFSLSALREAQNLAFTGLNLVARNECSRDGDPAEGGRRA
  FPLCQLPGAVHFLPLVQFFIGLHCQALQDLAAAKRSGAPGDSPTHSSCVSSGVETNPEDSVCILEGFSVT
  ALSILQHLVCHSGAVVSLLLSGVGADSAAGEGNRSLVHRLSDGDMTSALRGVADDQGQHPLLKMLLHLLA
  FSSAATGHLQASVLTQCLKVLVKLAENTSCDFLPRFQCVFQVLPKCLSPETPLPSVLLAVELLSLLADHD
  QLAPQLCSHSEGCLLLLLYMYITSRPDRVALETQWLQLEQEVVWLLAKLGVQSPLPPVTGSNCQCNVEVV
  RALTVMLHRQWLTVRRAGGPPRTDQQRRTVRCLRDTVLLLHGLSQKDKLFMMHCVEVLHQFDQVMPGVSM
  LIRGLPDVTDCEEAALDDLCAAETDVEDPEVECG
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001271022
• ORF Size: 1992 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001271022.1, NP_001257951.1
• RefSeq Size: 2419
• RefSeq ORF: 1995
• Locus ID: 84126
• MW: 72.8 kDa
• Gene Summary: This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012]