Neurobeachin (NBEA) (NM_001204197) Human Tagged ORF Clone

CAT#: RC233111

NBEA (Myc-DDK tagged) - Homo sapiens neurobeachin (NBEA), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: NBEA
• Synonyms: BCL8B; LYST2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC233111 representing NM_001204197
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTTCAGCGAGATACGAGCTGTATTTTCAAGACGTTACCTTCTACAAAACACTGCTTTGGAAGTATTTA
  TGGCAAACCGAACCTCAGTTATGTTTAATTTCCCTGATCAAGCAACAGTAAAAAAAGTTGTCTATAGCTT
  GCCTCGGGTTGGAGTAGGGACCAGCTATGGTCTGCCACAAGCCAGGAGGATATCATTGGCCACTCCTCGA
  CAGCTTTATAAATCTTCCAATATGACTCAGCGCTGGCAAAGAAGGGAAATTTCAAACTTCGAATATTTGA
  TGTTCCTTAATACTATTGCAGGACGGACATATAATGATCTGAACCAATATCCAGTGTTTCCGTGGGTGTT
  AACCAACTATGAATCAGAAGAGTTGGACCTGACTCTTCCAGGAAACTTCAGGGATCTATCAAAGCCAATT
  GGTGCTTTGAACCCCAAGAGAGCTGTGTTTTATGCAGAGCGTTATGAGACATGGGAAGATGATCAAAGCC
  CACCCTACCATTATAATACCCATTATTCAACAGCAACATCTACTTTATCCTGGCTTGTTCGAATTGAACC
  TTTCACAACCTTCTTCCTCAATGCAAATGATGGAAAATTTGATCATCCAGATCGAACCTTCTCATCCGTT
  GCAAGGTCTTGGAGAACTAGTCAGAGAGATACTTCTGATGTAAAGGAACTAATTCCAGAGTTCTACTACC
  TACCAGAGATGTTTGTCAACAGTAATGGATATAATCTTGGAGTCAGAGAAGATGAAGTAGTGGTAAATGA
  TGTTGATCTTCCCCCTTGGGCAAAAAAACCTGAAGACTTTGTGCGGATCAACAGGATGGCCCTAGAAAGT
  GAATTTGTTTCTTGCCAACTTCATCAGTGGATCGACCTTATATTTGGCTATAAGCAGCGAGGACCAGAAG
  CAGTTCGTGCTCTGAATGTTTTTCACTACTTGACTTATGAAGGCTCTGTGAACCTGGATAGTATCACTGA
  TCCTGTGCTCAGGGAGGCCATGGAGGCACAGATACAGAACTTTGGACAGACGCCATCTCAGTTGCTTATT
  GAGCCACATCCGCCTCGGAGCTCTGCCATGCACCTGTGTTTCCTTCCACAGAGTCCGCTCATGTTTAAAG
  ATCAGATGCAACAGGATGTGATAATGGTGCTGAAGTTTCCTTCAAATTCTCCAGTAACCCATGTGGCAGC
  CAACACTCTGCCCCACTTGACCATCCCCGCAGTGGTGACAGTGACTTGCAGCCGACTCTTTGCAGTGAAT
  AGATGGCACAACACAGTAGGCCTCAGAGGAGCTCCAGGATACTCCTTGGATCAAGCCCACCATCTTCCCA
  TTGAAATGGATCCATTAATAGCCAATAATTCAGGTGTAAACAAACGGCAGATCACAGACCTCGTTGACCA
  GAGTATACAAATCAATGCACATTGTTTTGTGGTAACAGCAGATAATCGCTATATTCTTATCTGTGGATTC
  TGGGATAAGAGCTTCAGAGTTTATTCTACAGAAACAGGGAAATTGACTCAGATTGTATTTGGCCATTGGG
  ATGTGGTCACTTGCTTGGCCAGGTCCGAGTCATACATTGGTGGGGACTGCTACATCGTGTCCGGATCTCG
  AGATGCCACCCTGCTGCTCTGGTACTGGAGTGGGCGGCACCATATCATAGGAGACAACCCTAACAGCAGT
  GACTATCCGGCACCAAGAGCCGTCCTCACAGGCCATGACCATGAAGTTGTCTGTGTTTCTGTCTGTGCAG
  AACTTGGGCTTGTTATCAGTGGTGCTAAAGAGGGCCCTTGCCTTGTCCACACCATCACTGGAGATTTGCT
  GAGAGCCCTTGAAGGACCAGAAAACTGCTTATTCCCACGCTTGATATCTGTCTCCAGCGAAGGCCACTGT
  ATCATATACTATGAACGAGGGCGATTCAGTAATTTCAGCATTAATGGGAAACTTTTGGCTCAAATGGAGA
  TCAATGATTCAACACGGGCCATTCTCCTGAGCAGTGACGGCCAGAACCTGGTCACCGGAGGGGACAATGG
  GGTAGTAGAGGTCTGGCAGGCCTGTGACTTCAAGCAACTGTACATTTACCCTGGATGTGATGCTGGCATT
  AGAGCAATGGACTTGTCCCATGACCAGAGGACTCTGATCACTGGCATGGCTTCTGGTAGCATTGTAGCTT
  TTAATATAGATTTTAATCGGTGGCATTATGAGCATCAGAACAGATAC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC233111 representing NM_001204197
  Red=Cloning site Green=Tags(s)
  
  MFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPR
  QLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPI
  GALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSTLSWLVRIEPFTTFFLNANDGKFDHPDRTFSSV
  ARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYNLGVREDEVVVNDVDLPPWAKKPEDFVRINRMALES
  EFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDPVLREAMEAQIQNFGQTPSQLLI
  EPHPPRSSAMHLCFLPQSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTIPAVVTVTCSRLFAVN
  RWHNTVGLRGAPGYSLDQAHHLPIEMDPLIANNSGVNKRQITDLVDQSIQINAHCFVVTADNRYILICGF
  WDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWYWSGRHHIIGDNPNSS
  DYPAPRAVLTGHDHEVVCVSVCAELGLVISGAKEGPCLVHTITGDLLRALEGPENCLFPRLISVSSEGHC
  IIYYERGRFSNFSINGKLLAQMEINDSTRAILLSSDGQNLVTGGDNGVVEVWQACDFKQLYIYPGCDAGI
  RAMDLSHDQRTLITGMASGSIVAFNIDFNRWHYEHQNRY
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001204197
• ORF Size: 2217 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001204197.1, NP_001191126.1
• RefSeq Size: 4107
• RefSeq ORF: 2220
• Locus ID: 26960
• MW: 84.5 kDa
• Gene Summary: This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. This gene and its expression are frequently disrupted in patients with multiple myeloma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants may exist, but their full-length nature has not been determined. [provided by RefSeq, Feb 2011]