Synphilin 1 (SNCAIP) (NM_001242935) Human Tagged ORF Clone

CAT#: RC234537

SNCAIP (Myc-DDK tagged) - Homo sapiens synuclein, alpha interacting protein (SNCAIP), transcript variant 1A

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: SNCAIP
• Synonyms: Sph1; SYPH1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC234537 representing NM_001242935
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACATATCTTATTCAGTCACATCACTCAAGACGATCCCAGAACTGTGCCGAAGATGTGATACGCAAAA
  CGAAGACAGATCAGAATGGTCAGTTGGAGTGCGTACGCTGGATGGTGAGCGAAACAGAAGCCATTGCAGA
  ACTGAGTTGTTCTAAGGATTTTCCAAGCCTTATTCATTACGCAGGTTGCTATGGCCAGGAAAAGATTCTT
  CTGTGGCTTCTTCAGTTTATGCAAGAACAGGGCATCTCGTTGGATGAAGTAGACCAGGATGGCAACAGTG
  CCGTTCACGTAGCCTCACAGCATGGCTACCTTGGATGCATACAGACCTTGGTTGAATATGGAGCAAATGT
  CACCATGCAGAACCACGCTGGGGAAAAGCCCTCCCAGAGCGCCGAGCGGCAGGGGCACACCCTGTGCTCC
  AGGTACCTGGTGGTGGTGGAGACCTGCATGTCGCTGGCCTCTCAAGTGGTGAAGTTAACCAAGCAGCTAA
  AGGAACAAACAGTAGAACGTGTCACGCTGCAGAACCAACTCCAACAATTTCTAGAAGCCCAGAAATCAGA
  GGGCAAGTCACTCCCTTCTTCACCCAGTTCACCATCCTCACCTGCCTCCAGAAAGTCCCAGTGGAAATCT
  CCAGATGCAGATGATGATTCTGTAGCCAAAAGCAAGCCAGGAGTCCAAGAGGGGATTCAGGTTCTTGGAA
  GCCTGTCAGCCTCCAGCCGGGCTAGACCCAAAGCAAAAGATGAAGATTCTGATAAAATCTTACGCCAGTT
  ATTGGGAAAGGAAATCTCAGAAAATGTCTGCACCCAGGAAAAACTGTCCTTGGAATTCCAGGATGCTCAG
  GCTTCCTCTAGAAATTCTAAAAAGATCCCACTGGAGAAGAGGGAACTGAAGTTAGCCAGGCTGAGACAGC
  TGATGCAGAGGTCACTGAGTGAGTCTGACACAGACTCCAACAACTCTGAGGACCCCAAGACTACCCCAGT
  GAGGAAGGCTGACCGACCAAGGCCGCAGCCCATTGTAGAAAGCGTAGAGAGTATGGACAGCGCAGAAAGC
  CTGCACCTGATGATTAAGAAACACACCTTGGCATCAGGGGGACGCAGGTTTCCTTTCAGCATCAAGGCCT
  CCAAATCCCTGGATGGCCACAGCCCATCTCCCACCTCAGAGAGCAGCGAACCAGACTTAGAATCCCAGTA
  TCCAGGCTCAGGGAGTATTCCTCCAAACCAGCCCTCTGGTGACCCTCAGCAGCCCAGCCCTGACAGTACT
  GCTGCCCAGAAAGTTGCCACAAGTCCCAAGAGTGCCCTCAAGTCTCCATCTTCCAAGCGTAGGACATCTC
  AGAACTTAAAACTGAGAGTTACCTTTGAGGAGCCTGTGGTGCAGATGGAGCAGCCTAGCCTTGAACTGAA
  TGGAGAAAAAGACAAAGATAAGGGCAGGACTCTCCAGCGGACCTCCACAAGTAACGAATCGGGGGATCAA
  CTGAAAAGGCCTTTTGGAGCCTTTCGATCTATCATGGAGACACTAAGTGGCAACCAAAACAATAATAATA
  ACTACCAGGCAGCCAACCAGCTGAAAACCTCTACATTGCCCTTGACCTCACTTGGGAGGAAGACAGATGC
  CAAGGGAAACCCTGCCAGCTCCGCTAGCAAAGGAAAGAATAAGGCAGAAATGTACAGCAGCTGCATCAAT
  CTTTCCTCTAACATGCTGATTGAAGAGCATCTGTGTAACGACACACGGCATAATGACATCAATAGAAAAA
  TGAAGAAATCCTACAGCATAAAGCACATTGCTGAGCCAGAGTCAAAAGAACTCTTCTTG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC234537 representing NM_001242935
  Red=Cloning site Green=Tags(s)
  
  MTYLIQSHHSRRSQNCAEDVIRKTKTDQNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCYGQEKIL
  LWLLQFMQEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERQGHTLCS
  RYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQFLEAQKSEGKSLPSSPSSPSSPASRKSQWKS
  PDADDDSVAKSKPGVQEGIQVLGSLSASSRARPKAKDEDSDKILRQLLGKEISENVCTQEKLSLEFQDAQ
  ASSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKTTPVRKADRPRPQPIVESVESMDSAES
  LHLMIKKHTLASGGRRFPFSIKASKSLDGHSPSPTSESSEPDLESQYPGSGSIPPNQPSGDPQQPSPDST
  AAQKVATSPKSALKSPSSKRRTSQNLKLRVTFEEPVVQMEQPSLELNGEKDKDKGRTLQRTSTSNESGDQ
  LKRPFGAFRSIMETLSGNQNNNNNYQAANQLKTSTLPLTSLGRKTDAKGNPASSASKGKNKAEMYSSCIN
  LSSNMLIEEHLCNDTRHNDINRKMKKSYSIKHIAEPESKELFL
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001242935
• ORF Size: 1809 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001242935.1, NM_001242935.2, NP_001229864.1
• RefSeq Size: 2588
• RefSeq ORF: 1812
• Locus ID: 9627
• Protein Pathways: Parkinson's disease
• MW: 67.1 kDa
• Gene Summary: This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]