FOXP1 (NM_001244816) Human Tagged ORF Clone

CAT#: RC234698

FOXP1 (Myc-DDK tagged) - Homo sapiens forkhead box P1 (FOXP1), transcript variant 9

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: FOXP1
• Synonyms: 12CC4; hFKH1B; HSPC215; MFH; QRF1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC234698 ORF sequence
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  RCATGATGCAAGAATCTGGGACTGAGACAAAAAGTAACGGTTCAGCCATCCAGAATGGGTCGGGCGGCAG
  CAACCACTTACTAGAGTGCGGCGGTCTTCGGGAGGGGCGGTCCAACGGAGAGACGCCGGCCGTGGACATC
  GGGGCAGCTGACCTCGCCCACGCCCAGCAGCAGCAGCAACAGGCACTTCAGGTGGCAAGACAGCTCCTTC
  TTCAGCAGCAACAGCAGCAGCAAGTTAGTGGATTAAAATCTCCCAAGAGGAATGACAAACAACCAGCTCT
  TCAGGTTCCCGTGTCAGTGGCTATGATGACACCTCAAGTTATCACTCCCCAGCAAATGCAGCAGATCCTC
  CAGCAACAAGTGCTGAGCCCTCAGCAGCTCCAGGTTCTCCTCCAGCAGCAGCAGGCCCTCATGCTTCAAC
  AGCAGCAGCTTCAAGAGTTTTATAAAAAACAACAGGAACAGTTGCAGCTTCAACTTTTACAACAACAACA
  TGCTGGAAAACAGCCTAAAGAGCAACAGCAGGTGGCTACCCAGCAGTTGGCTTTTCAGCAGCAGCTTTTA
  CAGATGCAGCAGTTACAGCAGCAGCACCTCCTGTCTTTGCAGCGCCAAGGCCTTCTGACAATTCAGCCCG
  GGCAGCCTGCCCTTCCCCTTCAACCTCTTGCTCAAGGCATGATTCCAACAGAACTGCAGCAGCTCTGGAA
  AGAAGTGACAAGTGCTCATACTGCAGAAGAAACCACAGGCAACAATCACAGCAGTTTGGATCTGACCACG
  ACATGTGTCTCCTCCTCTGCACCTTCCAAGACCTCCTTAATAATGAACCCACATGCCTCTACCAATGGAC
  AGCTCTCAGTCCACACTCCCAAAAGGGAAAGTTTGTCCCATGAGGAGCACCCCCATAGCCATCCTCTCTA
  TGGACATGGTGTATGCAAGTGGCCAGGCTGTGAAGCAGTGTGCGAAGATTTCCAATCATTTCTAAAACAT
  CTCAACAGTGAGCATGCGCTGGACGATAGAAGTACAGCCCAATGTAGAGTACAAATGCAGGTTGTACAGC
  AGTTAGAGCTACAGCTTGCAAAAGACAAAGAACGCCTGCAAGCCATGATGACCCACCTGCATGTGAAGTC
  TACAGAACCCAAAGCCGCCCCTCAGCCCTTGAATCTGGTATCAAGTGTCACTCTCTCCAAGTCCGCATCG
  GAGGCTTCTCCACAGAGCTTACCTCATACTCCAACGACCCCAACCGCCCCCCTGACTCCCGTCACCCAAG
  GCCCCTCTGTCATCACAACCACCAGCATGCACACGGTGGGACCCATCCGCAGGCGGTACTCAGACAAATA
  CAACGTGCCCATTTCGTCAGCAGATATTGCGCAGAACCAAGAATTTTATAAGAACGCAGAAGTTAGACCA
  CCATTTACATATGCATCTTTAATTAGGCAGGCCATTCTCGAATCTCCAGAAAAGCAGCTAACACTAAATG
  AGATCTATAACTGGTTCACACGAATGTTTGCTTACTTCCGACGCAACGCGGCCACGTGGAAGAATGCAGT
  GCGTCATAATCTTAGTCTTCACAAGTGTTTTGTGCGAGTAGAAAACGTTAAAGGGGCAGTATGGACAGTG
  GATGAAGTAGAATTCCAAAAACGAAGGCCACAAAAGATCAGTGGTAACCCTTCCCTTATTAAAAACATGC
  AGAGCAGCCACGCCTACTGCACACCTCTCAGTGCAGCTTTACAGGCTTCAATGGCTGAGAATAGTATACC
  TCTATACACTACCGCTTCCATGGGAAATCCCACTCTGGGCAACTTAGCCAGCGCAATACGGGAAGAGCTG
  AACGGGGCAATGGAGCATACCAACAGCAACGAGAGTGACAGCAGTCCAGGCAGATCTCCTATGCAAGCCG
  TGCATCCTGTACACGTCAAAGAAGAGCCCCTCGATCCAGAGGAAGCTGAAGGGCCCCTGTCCTTAGTGAC
  AACAGCCAACCACAGTCCAGATTTTGACCATGACAGAGATTACGAAGATGAACCAGTAAACGAGGACATG
  GAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC234698 protein sequence
  Red=Cloning site Green=Tags(s)
  
  X*CKNLGLRQKVTVQPSRMGRAAATTY*SAAVFGRGGPTERRRPWTSGQLTSPTPSSSSNRHFRWQDSSF
  FSSNSSSKLVD*NLPRGMTNNQLFRFPCQWL**HLKLSLPSKCSRSSSNKC*ALSSSRFSSSSSRPSCFN
  SSSFKSFIKNNRNSCSFNFYNNNMLENSLKSNSRWLPSSWLFSSSFYRCSSYSSSTSCLCSAKAF*QFSP
  GSLPFPFNLLLKA*FQQNCSSSGKK*QVLILQKKPQATITAVWI*PRHVSPPLHLPRPP***THMPLPMD
  SSQSTLPKGKVCPMRSTPIAILSMDMVYASGQAVKQCAKISNHF*NISTVSMRWTIEVQPNVEYKCRLYS
  S*SYSLQKTKNACKP**PTCM*SLQNPKPPLSP*IWYQVSLSPSPHRRLLHRAYLILQRPQPPP*LPSPK
  APLSSQPPACTRWDPSAGGTQTNTTCPFRQQILRRTKNFIRTQKLDHHLHMHL*LGRPFSNLQKSS*H*M
  RSITGSHECLLTSDATRPRGRMQCVIILVFTSVLCE*KTLKGQYGQWMK*NSKNEGHKRSVVTLPLLKTC
  RAATPTAHLSVQLYRLQWLRIVYLYTLPLPWEIPLWAT*PAQYGKS*TGQWSIPTATRVTAVQADLLCKP
  CILYTSKKSPSIQRKLKGPCP**QQPTTVQILTMTEITKMNQ*TRTW
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001244816
• ORF Size: 2031 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001244816.1, NP_001231745.1
• RefSeq Size: 7007 bp
• RefSeq ORF: 2034 bp
• Locus ID: 27086
• Protein Families: Transcription Factors
• MW: 75.3 kDa
• Gene Summary: This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]