DNAJC6 (NM_001256864) Human Tagged ORF Clone

CAT#: RC235088

DNAJC6 (Myc-DDK tagged) - Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 6 (DNAJC6), transcript variant 1

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: DNAJC6
• Synonyms: DJC6; PARK19
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC235088 representing NM_001256864
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGCCTCCTCGGGAGCTACCGGAAAAAGACCAGCAACGATGGTTATGAATCTTTGCAGCTGGTGGACA
  GTAACGGGGACTTAAGTGCGGGAAGCGGCGGGGTTGGCGGCAAGCAGAGAGTGAACGCCGGGGCAGCGGC
  GCGGAGTCCCGCCCGACAGCCTCCGGACCGCGCCAGCACCATGGACAGCTCAGGTGCCTCATCTCCAGAC
  ATGGAGCCCAGCTATGGGGGAGGTCTCTTTGACATGGTAAAAGGAGGTGCAGGGAGGCTCTTTAGTAACC
  TAAAGGACAACTTGAAAGACACCCTCAAAGACACATCTTCTAGAGTGATACAATCTGTGACCAGCTACAC
  AAAGGGAGATTTAGACTTCACTTATGTTACCTCCAGAATTATTGTGATGTCCTTTCCTCTGGACAATGTT
  GACATAGGATTCAGGAATCAGGTTGATGACATTCGAAGCTTTTTGGATTCCAGACATCTTGACCACTACA
  CAGTATACAATCTGTCACCTAAGTCTTATCGAACTGCCAAGTTTCACAGCCGGGTCTCAGAATGCAGTTG
  GCCCATTAGGCAGGCTCCCAGTCTGCACAACCTTTTTGCTGTGTGTCGGAATATGTATAACTGGCTACTG
  CAGAATCCCAAAAATGTCTGTGTTGTCCACTGCTTGGATGGACGGGCGGCATCATCAATTCTGGTTGGTG
  CTATGTTCATTTTCTGTAATCTCTACTCTACTCCTGGCCCAGCCATTCGATTGCTATATGCAAAGCGACC
  AGGAATTGGACTTTCACCATCCCATAGGAGATACCTGGGCTATATGTGTGACCTACTGGCAGACAAGCCC
  TACCGCCCTCACTTCAAGCCTCTCACAATTAAGTCGATCACTGTCAGTCCAATACCCTTTTTCAACAAAC
  AGAGGAATGGATGTCGCCCTTACTGTGATGTACTCATTGGAGAAACCAAAATATATTCGACTTGCACAGA
  TTTTGAACGAATGAAAGAATATCGTGTCCAAGATGGAAAAATCTTCATTCCCTTGAACATCACTGTGCAA
  GGAGACGTGGTTGTTTCCATGTATCACTTGAGGTCAACCATTGGGAGCCGGCTACAGGCTAAGGTGACCA
  ACACACAGATATTCCAGCTTCAGTTTCACACTGGATTCATACCACTGGACACAACAGTTTTAAAGTTCAC
  CAAGCCTGAGTTAGATGCATGTGATGTACCAGAAAAATATCCTCAGCTATTTCAGGTGACACTGGATGTA
  GAACTACAGCCCCATGACAAAGTAATAGACTTAACTCCACCATGGGAACATTACTGCACAAAAGATGTCA
  ATCCCAGCATCCTCTTCTCTTCTCACCAGGAACATCAAGATACGCTGGCCTTAGGAGGACAGGCTCCAAT
  AGATATCCCTCCAGACAACCCCAGGCATTACGGACAAAGTGGTTTCTTTGCCTCTCTCTGTTGGCAAGAT
  CAGAAATCGGAGAAGTCATTCTGTGAGGAGGACCACGCTGCCCTAGTGAATCAGGAAAGTGAGCAATCAG
  ATGATGAACTTCTGACACTTTCCAGTCCGCATGGCAATGCCAATGGTGACAAGCCTCATGGAGTCAAGAA
  GCCCAGCAAAAAGCAGCAGGAGCCAGCAGCCCCTCCACCCCCTGAGGATGTGGACCTTTTGGGCCTGGAA
  GGGTCTGCAATGAGTAACAGCTTCTCTCCGCCAGCGGCTCCTCCCACCAATTCTGAACTACTGAGTGACC
  TGTTTGGGGGTGGAGGTGCAGCTGGTCCCACCCAGGCTGGACAGTCAGGAGTGGAAGATGTGTTTCATCC
  TAGTGGACCTGCGTCTACCCAGTCAACACCACGCCGCTCTGCCACCTCCACCTCTGCGTCTCCAACCCTA
  AGAGTGGGAGAAGGTGCCACCTTTGACCCATTTGGAGCACCTTCTAAACCATCAGGTCAGGATTTGCTGG
  GTTCTTTTCTGAACACATCCAGTGCTTCCAGTGACCCCTTTCTCCAGCCAACAAGAAGTCCTTCGCCCAC
  AGTACATGCTTCTAGTACGCCTGCTGTGAACATTCAGCCAGATGTTTCTGGAGGTTGGGACTGGCATGCT
  AAACCAGGAGGCTTTGGAATGGGAAGCAAGTCAGCTGCCACCAGCCCAACCGGATCCTCGCATGGTACTC
  CCACCCATCAAAGCAAACCCCAGACTCTGGATCCTTTTGCCGACCTTGGGACACTAGGTAGTTCTTCCTT
  TGCCAGCAAACCCACCACACCAACTGGATTGGGTGGAGGATTCCCGCCTCTCAGCTCGCCACAGAAGGCG
  TCTCCCCAGCCTATGGGTGGCGGGTGGCAGCAGGGAGGTGCCTACAACTGGCAGCAGCCACAGCCTAAGC
  CTCAGCCCAGCATGCCCCACTCCTCTCCCCAGAACCGACCCAACTACAACGTGAGCTTCTCAGCCATGCC
  TGGGGGCCAGAACGAACGTGGGAAAGGATCAAGTAATTTGGAAGGGAAACAAAAAGCAGCTGATTTTGAA
  GACCTACTCTCTGGTCAAGGTTTCAATGCTCACAAAGACAAAAAGGGGCCTCGGACAATAGCTGAGATGA
  GAAAGGAGGAAATGGCCAAGGAAATGGATCCTGAGAAATTAAAGATTCTGGAATGGATTGAAGGCAAAGA
  AAGAAATATCAGAGCCCTTCTTTCCACGATGCATACCGTACTATGGGCTGGGGAGACCAAGTGGAAACCA
  GTTGGCATGGCAGACCTGGTAACACCAGAGCAGGTGAAGAAGGTGTACAGGAAGGCTGTCCTGGTGGTGC
  ACCCAGATAAAGCTACTGGGCAACCCTATGAACAATACGCAAAGATGATTTTCATGGAGCTCAATGATGC
  CTGGTCTGAATTTGAAAACCAAGGCCAAAAGCCCTTATAT
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC235088 representing NM_001256864
  Red=Cloning site Green=Tags(s)
  
  MSLLGSYRKKTSNDGYESLQLVDSNGDLSAGSGGVGGKQRVNAGAAARSPARQPPDRASTMDSSGASSPD
  MEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVTSYTKGDLDFTYVTSRIIVMSFPLDNV
  DIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLL
  QNPKNVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAIRLLYAKRPGIGLSPSHRRYLGYMCDLLADKP
  YRPHFKPLTIKSITVSPIPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQ
  GDVVVSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVTLDV
  ELQPHDKVIDLTPPWEHYCTKDVNPSILFSSHQEHQDTLALGGQAPIDIPPDNPRHYGQSGFFASLCWQD
  QKSEKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGDKPHGVKKPSKKQQEPAAPPPPEDVDLLGLE
  GSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQSGVEDVFHPSGPASTQSTPRRSATSTSASPTL
  RVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGGWDWHA
  KPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPFADLGTLGSSSFASKPTTPTGLGGGFPPLSSPQKA
  SPQPMGGGWQQGGAYNWQQPQPKPQPSMPHSSPQNRPNYNVSFSAMPGGQNERGKGSSNLEGKQKAADFE
  DLLSGQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKP
  VGMADLVTPEQVKKVYRKAVLVVHPDKATGQPYEQYAKMIFMELNDAWSEFENQGQKPLY
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001256864
• ORF Size: 2910 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001256864.1, NP_001243793.1
• RefSeq Size: 5968
• RefSeq ORF: 2913
• Locus ID: 9829
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis
• MW: 106.1 kDa
• Gene Summary: DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]). [supplied by OMIM, Mar 2008]