NALP12 (NLRP12) (NM_001277129) Human Tagged ORF Clone
CAT#: RC235118
- TrueORF®
NLRP12 (Myc-DDK tagged) - Homo sapiens NLR family, pyrin domain containing 12 (NLRP12), transcript variant 4
"NM_001277129" in other vectors (2)
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | NLRP12 |
Synonyms | CLR19.3; FCAS2; NALP12; PAN6; PYPAF7; RNO; RNO2 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC235118 representing NM_001277129
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCTACGAACCGCAGGCAGGGACGGCCTCTGTCGCCTGTCCACCTACTTGGAAGAACTCGAGGCTGTGG AACTGAAGAAGTTCAAGTTATACCTGGGGACCGCGACAGAGCTGGGAGAAGGCAAGATCCCCTGGGGAAG CATGGAGAAGGCCGGTCCCCTGGAAATGGCCCAGCTGCTCATCACCCACTTCGGGCCAGAGGAGGCCTGG AGGTTGGCTCTCAGCACCTTTGAGCGGATAAACAGGAAGGACCTGTGGGAGAGAGGACAGAGAGAGGACC TGGTGAGGGATACCCCACCTGGTGGCCCGTCCTCACTTGGGAACCAGTCAACATGCCTTCTGGAAGTCTC TCTTGTCACTCCAAGAAAAGATCCCCAGGAAACCTACAGGGACTATGTCCGCAGGAAATTCCGGCTCATG GAAGACCGCAATGCGCGCCTAGGGGAATGTGTCAACCTCAGCCACCGGTACACCCGGCTCCTGCTGGTGA AGGAGCACTCAAACCCCATGCAGGTCCAGCAGCAGCTTCTGGACACAGGCCGGGGACACGCGAGGACCGT GGGACACCAGGCTAGCCCCATCAAGATAGAGACCCTCTTTGAGCCAGACGAGGAGCGCCCCGAGCCACCG CGCACCGTGGTCATGCAAGGCGCGGCAGGGATAGGCAAGTCCATGCTGGCACACAAGGTGATGCTGGACT GGGCGGACGGGAAGCTCTTCCAAGGCAGATTTGATTATCTCTTCTACATCAACTGCAGGGAGATGAACCA GAGTGCCACGGAATGCAGCATGCAAGACCTCATCTTCAGCTGCTGGCCTGAGCCCAGCGCGCCTCTCCAG GAGCTCATCCGAGTTCCCGAGCGCCTCCTTTTCATCATCGACGGCTTCGATGAGCTCAAGCCTTCTTTCC ACGATCCTCAGGGACCCTGGTGCCTCTGCTGGGAGGAGAAACGGCCCACGGAGCTGCTTCTTAACAGCTT AATTCGGAAGAAGCTGCTCCCTGAGCTATCTTTGCTCATCACCACACGGCCCACGGCTTTGGAGAAGCTC CACCGTCTGCTGGAGCACCCCAGGCATGTGGAGATCCTGGGCTTCTCTGAGGCAGAAAGGAAGGAATACT TCTACAAGTATTTCCACAATGCAGAGCAGGCGGGCCAAGTCTTCAATTACGTGAGGGACAACGAGCCTCT CTTCACCATGTGCTTCGTCCCCCTGGTGTGCTGGGTGGTGTGTACCTGCCTCCAGCAGCAGCTGGAGGGT GGGGGGCTGTTGAGACAGACGTCCAGGACCACCACTGCAGTGTACATGCTCTACCTGCTGAGTCTGATGC AACCCAAGCCGGGGGCCCCGCGCCTCCAGCCCCCACCCAACCAGAGAGGGTTGTGCTCCTTGGCGGCAGA TGGGCTCTGGAATCAGAAAATCCTATTTGAGGAGCAGGACCTCCGGAAGCACGGCCTAGACGGGGAAGAC GTCTCTGCCTTCCTCAACATGAACATCTTCCAGAAGGACATCAACTGTGAGAGGTACTACAGCTTCATCC ACTTGAGTTTCCAGGAATTCTTTGCAGCTATGTACTATATCCTGGACGAGGGGGAGGGCGGGGCAGGCCC AGACCAGGACGTGACCAGGCTGTTGACCGAGTACGCGTTTTCTGAAAGGAGCTTCCTGGCACTCACCAGC CGCTTCCTGTTTGGACTCCTGAACGAGGAGACCAGGAGCCACCTGGAGAAGAGTCTCTGCTGGAAGGTCT CGCCGCACATCAAGATGGACCTGTTGCAGTGGATCCAAAGCAAAGCTCAGAGCGACGGCTCCACCCTGCA GCAGGGCTCCTTGGAGTTCTTCAGCTGCTTGTACGAGATCCAGGAGGAGGAGTTTATCCAGCAGGCCCTG AGCCACTTCCAGGTGATCGTGGTCAGCAACATTGCCTCCAAGATGGAGCACATGGTCTCCTCGTTCTGTC TGAAGCGCTGCAGGAGCGCCCAGGTGCTGCACTTGTATGGCGCCACCTACAGCGCGGACGGGGAAGACCG CGCGAGGTGCTCCGCAGGAGCGCACACGCTGTTGGTGCAGCTACCAGAGAGGACCGTTCTGCTGGACGCC TACAGTGAACATCTGGCAGCGGCCCTGTGCACCAATCCAAACCTGATAGAGCTGTCTCTGTACCGAAATG CCCTGGGCAGCCGGGGGGTGAAGCTGCTCTGTCAAGGACTCAGACACCCCAACTGCAAACTTCAGAACCT GAGGCTGAAGAGGTGCCGCATCTCCAGCTCAGCCTGCGAGGACCTCTCTGCAGCTCTCATAGCCAATAAG AATTTGACAAGGATGGATCTCAGTGGCAACGGCGTTGGATTCCCAGGCATGATGCTGCTTTGCGAGGGCC TGCGGCATCCCCAATGCAGGCTGCAGATGATTCAGTTGAGGAAGTGTCAGCTGGAGTCCGGGGCTTGTCA GGAGATGGCTTCTGTGCTCGGCACCAACCCACATCTGGTTGAGTTGGACCTGACAGGAAATGCACTGGAG GATTTGGGCCTGAGGTTACTATGCCAGGGACTGAGGCACCCAGTCTGCAGACTACGGACTTTGTGGCTGA AGATCTGCCGCCTCACTGCTGCTGCCTGTGACGAGCTGGCCTCAACTCTCAGTGTGAACCAGAGCCTGAG AGAGCTGGACCTGAGCCTGAATGAGCTGGGGGACCTCGGGGTGCTGCTGCTGTGTGAGGGCCTCAGGCAT CCCACGTGCAAGCTCCAGACCCTGCGGCTGGATAGCTGTGGCCTCACAGCCAAGGCTTGTGAGAATCTTT ACTTCACCCTGGGGATCAACCAGACCTTGACCGACCTTTACCTGACCAACAACGCCCTAGGGGACACAGG TGTCCGACTGCTTTGCAAGCGGCTGAGCCATCCTGGCTGCAAACTCCGAGTCCTCTGGTTATTTGGGATG GACCTGAATAAAATGACCCACAGTAGGTTGGCAGCGCTTCGAGTAACAAAACCTTATTTGGACATTGGCT GC AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGATAAGGTTTAA >RC235118 representing NM_001277129
Red=Cloning site Green=Tags(s) MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLGTATELGEGKIPWGSMEKAGPLEMAQLLITHFGPEEAW RLALSTFERINRKDLWERGQREDLVRDTPPGGPSSLGNQSTCLLEVSLVTPRKDPQETYRDYVRRKFRLM EDRNARLGECVNLSHRYTRLLLVKEHSNPMQVQQQLLDTGRGHARTVGHQASPIKIETLFEPDEERPEPP RTVVMQGAAGIGKSMLAHKVMLDWADGKLFQGRFDYLFYINCREMNQSATECSMQDLIFSCWPEPSAPLQ ELIRVPERLLFIIDGFDELKPSFHDPQGPWCLCWEEKRPTELLLNSLIRKKLLPELSLLITTRPTALEKL HRLLEHPRHVEILGFSEAERKEYFYKYFHNAEQAGQVFNYVRDNEPLFTMCFVPLVCWVVCTCLQQQLEG GGLLRQTSRTTTAVYMLYLLSLMQPKPGAPRLQPPPNQRGLCSLAADGLWNQKILFEEQDLRKHGLDGED VSAFLNMNIFQKDINCERYYSFIHLSFQEFFAAMYYILDEGEGGAGPDQDVTRLLTEYAFSERSFLALTS RFLFGLLNEETRSHLEKSLCWKVSPHIKMDLLQWIQSKAQSDGSTLQQGSLEFFSCLYEIQEEEFIQQAL SHFQVIVVSNIASKMEHMVSSFCLKRCRSAQVLHLYGATYSADGEDRARCSAGAHTLLVQLPERTVLLDA YSEHLAAALCTNPNLIELSLYRNALGSRGVKLLCQGLRHPNCKLQNLRLKRCRISSSACEDLSAALIANK NLTRMDLSGNGVGFPGMMLLCEGLRHPQCRLQMIQLRKCQLESGACQEMASVLGTNPHLVELDLTGNALE DLGLRLLCQGLRHPVCRLRTLWLKICRLTAAACDELASTLSVNQSLRELDLSLNELGDLGVLLLCEGLRH PTCKLQTLRLDSCGLTAKACENLYFTLGINQTLTDLYLTNNALGDTGVRLLCKRLSHPGCKLRVLWLFGM DLNKMTHSRLAALRVTKPYLDIGC SGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-RsrII
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001277129 |
ORF Size | 3012 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001277129.1, NP_001264058.1 |
RefSeq Size | 3709 |
RefSeq ORF | 3015 |
Locus ID | 91662 |
MW | 114.3 kDa |
Gene Summary | This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013] |
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