NPSR1 (NM_001300933) Human Tagged ORF Clone

CAT#: RC237759

NPSR1 (myc-DDK-tagged) - Human neuropeptide S receptor 1 (NPSR1), transcript variant 3

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: NPSR1
• Synonyms: ASRT2; GPR154; GPRA; NPSR; PGR14; VRR1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC237759 representing NM_001300933
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCAGCCAACTTCACAGAGGGCAGCTTCGATTCCAGTGGGACCGGGCAGACGCTGGATTCTTCCCCAG
  TGGCTTGCACTGAAACAGTGACTTTTACTGAAGTGGTGGAAGGAAAGGAATGGGGTTCCTTCTACTACTC
  CTTTAAGACTGAGCAATTGATAACTCTGTGGGTCCTCTTTGTTTTTACCATTGTTGGAAACTCCGTTGTG
  CTTTTTTCCACATGGAGGAGAAAGAAGAAGTCAAGAATGACCTTCTTTGTGACTCAGCTGGCCATCACAG
  ATATTAATTGGCGATTCACTGGAGACTTCACGGCACCTGACCTGGTTTGCCGAGTGGTCCGCTATTTGCA
  GGTTGTGCTGCTCTACGCCTCTACCTACGTCCTGGTGTCCCTCAGCATAGACAGATACCATGCCATCGTC
  TACCCCATGAAGTTCCTTCAAGGAGAAAAGCAAGCCAGGGTCCTCATTGTGATCGCCTGGAGCCTGTCTT
  TTCTGTTCTCCATTCCCACCCTGATCATATTTGGGAAGAGGACACTGTCCAACGGTGAAGTGCAGTGCTG
  GGCCCTGTGGCCTGACGACTCCTACTGGACCCCATACATGACCATCGTGGCCTTCCTGGTGTACTTCATC
  CCTCTGACAATCATCAGCATCATGTATGGCATTGTGATCCGAACTATTTGGATTAAAAGCAAAACCTACG
  AAACAGTGATTTCCAACTGCTCAGATGGGAAACTGTGCAGCAGCTATAACCGAGGACTCATCTCAAAGGC
  AAAAATCAAGGCTATCAAGTATAGCATCATCATCATTCTTGCCTTCATCTGCTGTTGGAGTCCATACTTC
  CTGTTTGACATTTTGGACAATTTCAACCTCCTTCCAGACACCCAGGAGCGTTTCTATGCCTCTGTGATCA
  TTCAGAACCTGCCAGCATTGAATAGTGCCATCAACCCCCTCATCTACTGTGTCTTCAGCAGCTCCATCTC
  TTTCCCCTGCAGGGTCATCCGTCTCCGTCAGCTCCAGGAGGCTGCGCTAATGCTCTGCCCTCAACGAGAG
  AACTGGAAGGGTACTTGGCCAGGTGTACCTTCCTGGGCTCTTCCAAGG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC237759 representing NM_001300933
  Red=Cloning site Green=Tags(s)
  
  MPANFTEGSFDSSGTGQTLDSSPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLFVFTIVGNSVV
  LFSTWRRKKKSRMTFFVTQLAITDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIV
  YPMKFLQGEKQARVLIVIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFI
  PLTIISIMYGIVIRTIWIKSKTYETVISNCSDGKLCSSYNRGLISKAKIKAIKYSIIIILAFICCWSPYF
  LFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSSISFPCRVIRLRQLQEAALMLCPQRE
  NWKGTWPGVPSWALPR
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001300933
• ORF Size: 1098 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001300933.1, NP_001287862.1
• RefSeq Size: 1423
• RefSeq ORF: 1101
• Locus ID: 387129
• Protein Families: Druggable Genome, Transmembrane
• MW: 42.4 kDa
• Gene Summary: This gene encodes a member of the vasopressin/oxytocin subfamily of G protein-coupled receptors. The encoded membrane protein acts as a receptor for neuropeptide S and affects a variety of cellular processes through its signaling. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Polymorphisms in this gene have also been associated with asthma susceptibility, panic disorders, inflammatory bowel disease, and rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]