WDR48 (NM_001303402) Human Tagged ORF Clone

CAT#: RC239027

WDR48 (myc-DDK-tagged) - Human WD repeat domain 48 (WDR48), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: WDR48
• Synonyms: P80; SPG60; UAF1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC239027 representing NM_001303402
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGTGTCAATCAGCACAAGTAATATCTGCTTCTTCTGACACGACAGTAAAAGTATGGAATGCACACA
  AGGGATTTTGCATGTCAACATTAAGGACACATAAGGATTACGTAAAGGCCTTAGCATATGCCAAGGATAA
  AGAACTAGTAGCATCAGCTGGGTTGGACAGACAAATATTCCTTTGGGATGTGAATACTCTAACAGCATTG
  ACTGCCTCAAATAACACTGTCACAACTTCTTCTTTAAGTGGAAACAAAGATTCCATTTATAGCCTGGCCA
  TGAATCAACTGGGAACAATCATTGTATCAGGGTCCACTGAAAAGGTGTTACGGGTATGGGATCCAAGAAC
  ATGTGCAAAACTAATGAAGCTTAAAGGGCACACGGATAATGTGAAGGCATTGCTATTAAACAGAGATGGC
  ACGCAATGCCTGTCAGGCAGTTCTGATGGGACAATTCGCCTTTGGTCCCTTGGCCAGCAGAGATGTATAG
  CAACATACCGAGTCCATGATGAAGGTGTTTGGGCGCTGCAAGTCAATGATGCCTTCACACATGTGTATTC
  TGGTGGAAGGGACAGGAAGATTTATTGTACAGACCTAAGAAACCCTGACATTCGGGTGCTAATTTGTGAA
  GAAAAAGCACCAGTTCTCAAGATGGAGCTTGATAGATCAGCTGATCCTCCTCCTGCAATTTGGGTTGCAA
  CAACTAAGTCTACAGTAAATAAATGGACTTTGAAAGGAATTCATAATTTTAGAGCCTCTGGAGATTATGA
  CAATGACTGTACAAATCCTATAACACCTCTTTGTACACAACCTGACCAGGTTATTAAAGGGGGTGCTAGT
  ATTATTCAGTGCCACATTCTTAATGATAAGAGACATATATTAACCAAAGATACCAATAATAATGTGGCAT
  ATTGGGATGTATTGAAGGCATGTAAAGTTGAAGATCTGGGCAAAGTGGATTTTGAAGATGAAATTAAGAA
  AAGATTTAAAATGGTGTATGTGCCAAATTGGTTCTCAGTAGACTTAAAAACAGGGATGTTAACTATTACT
  TTGGATGAAAGTGATTGTTTTGCTGCCTGGGTTTCTGCAAAAGATGCTGGTTTCAGCAGCCCTGATGGGT
  CAGATCCAAAATTGAATTTAGGAGGACTTTTACTCCAAGCACTCCTGGAATATTGGCCTAGAACACATGT
  GAATCCAATGGATGAAGAGGAAAATGAAGTAAACCATGTAAATGGGGAGCAGGAGAACCGAGTGCAGAAG
  GGAAATGGATATTTTCAAGTGCCCCCACATACACCCGTGATCTTTGGTGAAGCTGGAGGTCGCACACTGT
  TCAGGCTGCTCTGCCGAGATTCCGGGGGTGAGACTGAGTCTATGCTTCTTAATGAAACAGTGCCACAATG
  GGTAATTGACATCACTGTGGATAAAAATATGCCCAAATTCAACAAAATTCCTTTCTACCTCCAACCTCAT
  GCATCTTCAGGAGCAAAAACCTTAAAAAAAGATAGACTCTCTGCTAGTGACATGCTCCAAGTCCGAAAAG
  TTATGGAACATGTTTATGAAAAAATTATCAACTTGGATAATGAGTCTCAAACCACTAGCTCTTCTAATAA
  TGAAAAACCAGGAGAACAGGAAAAAGAAGAAGATATTGCTGTGTTGGCAGAGGAGAAAATTGAACTTTTG
  TGCCAGGACCAGGTTTTGGATCCAAATATGGACCTTCGAACAGTGAAACACTTCATATGGAAGAGCGGTG
  GAGACCTCACCCTCCATTACCGTCAGAAGTCCACG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC239027 representing NM_001303402
  Red=Cloning site Green=Tags(s)
  
  MECQSAQVISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTAL
  TASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDG
  TQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICE
  EKAPVLKMELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGGAS
  IIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGKVDFEDEIKKRFKMVYVPNWFSVDLKTGMLTIT
  LDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVNPMDEEENEVNHVNGEQENRVQK
  GNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMPKFNKIPFYLQPH
  ASSGAKTLKKDRLSASDMLQVRKVMEHVYEKIINLDNESQTTSSSNNEKPGEQEKEEDIAVLAEEKIELL
  CQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001303402
• ORF Size: 1785 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001303402.1, NP_001290331.1
• RefSeq Size: 3948
• RefSeq ORF: 1788
• Locus ID: 57599
• MW: 67.2 kDa
• Gene Summary: The protein encoded by this gene has been shown to interact with ubiquitin specific peptidase 1 (USP1), activating the deubiquitinating activity of USP1 and allowing it to remove the ubiquitin moiety from monoubiquitinated FANCD2. FANCD2 is ubiquitinated in response to DNA damage. [provided by RefSeq, Sep 2016]