IGF2BP2 (NM_001291869) Human Tagged ORF Clone

CAT#: RC239064

IGF2BP2 (myc-DDK-tagged) - Human insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2), transcript variant 3

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: IGF2BP2
• Synonyms: IMP-2; IMP2; VICKZ2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC239064 representing NM_001291869
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGATGAACAAGCTTTACATCGGGAACCTGAGCCCCGCCGTCACCGCCGACGACCTCCGGCAGCTCTTTG
  GGGACAGGAAGCTGCCCCTGGCGGGACAGGTCCTGCTGAAGTCCGGCTACGCCTTCGTGGACTACCCCGA
  CCAGAACTGGGCCATCCGCGCCATCGAGACCCTCTCGGGTAAAGTGGAATTGCATGGGAAAATCATGGAA
  GTTGATTACTCAGTCTCTAAAAAGCTAAGGAGCAGGAAAATTCAGATTCGAAACATCCCTCCTCACCTGC
  AGTGGGAGGTGTTGGATGGACTTTTGGCTCAATATGGGACAGTGGAGAATGTGGAACAAGTTTTTGCCTT
  TTCCCTAGTCAACACAGACACAGAAACCGCCGTTGTCAACGTCACATATGCAACAAGAGAAGAAGCAAAA
  ATAGCCATGGAGAAGCTAAGCGGGCATCAGTTTGAGAACTACTCCTTCAAGATTTCCTACATCCCGGATG
  AAGAGGTGAGCTCCCCTTCGCCCCCTCAGCGAGCCCAGCGTGGGGACCACTCTTCCCGGGAGCAAGGCCA
  CGCCCCTGGGGGCACTTCTCAGGCCAGACAGATTGATTTCCCGCTGCGGATCCTGGTCCCCACCCAGTTT
  GTTGGTGCCATCATCGGAAAGGAGGGCTTGACCATAAAGAACATCACTAAGCAGACCCAGTCCCGGGTAG
  ATATCCATAGAAAAGAGAACTCTGGAGCTGCAGAGAAGCCTGTCACCATCCATGCCACCCCAGAGGGGAC
  TTCTGAAGCATGCCGCATGATTCTTGAAATCATGCAGAAAGAGGCAGATGAGACCAAACTAGCCGAAGAG
  ATTCCTCTGAAAATCTTGGCACACAATGGCTTGGTTGGAAGACTGATTGGAAAAGAAGGCAGAAATTTGA
  AGAAAATTGAACATGAAACAGGGACCAAGATAACAATCTCATCTTTGCAGGATTTGAGCATATACAACCC
  GGAAAGAACCATCACTGTGAAGGGCACAGTTGAGGCCTGTGCCAGTGCTGAGATAGAGATTATGAAGAAG
  CTGCGTGAGGCCTTTGAAAATGATATGCTGGCTGTTAACCAACAAGCCAATCTGATCCCAGGGTTGAACC
  TCAGCGCACTTGGCATCTTTTCAACAGGACTGTCCGTGCTATCTCCACCAGCAGGGCCCCGCGGAGCTCC
  CCCCGCTGCCCCCTACCACCCCTTCACTACCCACTCCGGATACTTCTCCAGCCTGTACCCCCATCACCAG
  TTTGGCCCGTTCCCGCATCATCACTCTTATCCAGAGCAGGAGATTGTGAATCTCTTCATCCCAACCCAGG
  CTGTGGGCGCCATCATCGGGAAGAAGGGGGCACACATCAAACAGCTGGCGAGATTCGCCGGAGCCTCTAT
  CAAGATTGCCCCTGCGGAAGGCCCAGACGTCAGCGAAAGGATGGTCATCATCACCGGGCCACCGGAAGCC
  CAGTTCAAGGCCCAGGGACGGATCTTTGGGAAACTGAAAGAGGAAAACTTCTTTAACCCCAAAGAAGAAG
  TGAAGCTGGAAGCGCATATCAGAGTGCCCTCTTCCACAGCTGGCCGGGTGATTGGCAAAGGTGGCAAGAC
  CGTGAACGAACTGCAGAACTTAACCAGTGCAGAAGTCATCGTGCCTCGTGACCAAACGCCAGATGAAAAT
  GAGGAAGTGATCGTCAGAATTATCGGGCACTTCTTTGCTAGCCAGACTGCACAGCGCAAGATCAGGGAAA
  TTGTACAACAGGTGAAGCAGCAGGAGCAGAAATACCCTCAGGGAGTCGCCTCACAGCGCAGCAAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC239064 representing NM_001291869
  Red=Cloning site Green=Tags(s)
  
  MMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGKVELHGKIME
  VDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVFAFSLVNTDTETAVVNVTYATREEAK
  IAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQF
  VGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEE
  IPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKK
  LREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQ
  FGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEA
  QFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDEN
  EEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001291869
• ORF Size: 1815 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001291869.1, NM_001291869.2, NP_001278798.1
• RefSeq Size: 3696
• RefSeq ORF: 1818
• Locus ID: 10644
• MW: 67.2 kDa
• Gene Summary: This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016]