AMOTL2 (NM_001278683) Human Tagged ORF Clone

CAT#: RC239657

AMOTL2 (myc-DDK-tagged) - Human angiomotin like 2 (AMOTL2), transcript variant 1

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: AMOTL2
• Synonyms: LCCP
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC239657 representing NM_001278683
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACTGGGCGAAAAGCCAGCGGTGGCACACCTTGCACTCTGCGTAAAGGGGCGCCTATTATCACCTTGG
  GGAAGAACTGGACAGAGCGCCTGGCGGCGGGTGATTCAGTTGGGTGCTCTGGGGCCAGGTGCCACCGGCC
  ATTGTCCAGGCAGCTGTGTGCAAGCCAAAGAAGCATGAGGACACTGGAAGACTCCTCGGGGACAGTCCTG
  CACCGCCTCATCCAGGAGCAGCTGCGCTACGGCAACCTGACTGAGACGCGCACGCTGCTAGCCATCCAGC
  AGCAGGCCCTGAGGGGTGGGGCTGGAACTGGGGGTACAGGGAGCCCCCAGGCCTCCCTGGAGATCCTGGC
  CCCAGAGGACAGTCAGGTGCTGCAGCAGGCCACCAGGCAGGAGCCCCAGGGCCAGGAGCACCAGGGCGGT
  GAGAACCACCTGGCAGAGAACACCCTCTACCGGCTATGCCCACAGCCCAGCAAGGGAGAGGAGCTGCCCA
  CCTATGAGGAGGCCAAAGCCCACTCGCAGTACTATGCGGCCCAGCAGGCAGGGACCCGGCCACATGCGGG
  GGACCGAGATCCCCGTGGGGCCCCGGGAGGCAGTCGGAGGCAGGACGAGGCCCTGCGGGAGCTGAGGCAT
  GGGCACGTGCGCTCGTTGAGTGAACGGCTCCTTCAGTTGTCCCTGGAGAGGAACGGCGCCCGGGCCCCCA
  GCCACATGAGCTCCTCCCACAGCTTCCCACAGCTGGCCCGCAACCAGCAGGGCCCCCCACTGAGGGGCCC
  CCCTGCTGAGGGCCCAGAGTCCCGAGGACCCCCACCTCAGTACCCTCATGTTGTACTAGCTCATGAGACC
  ACCACTGCTGTCACTGACCCACGGTACCGTGCCCGCGGCAGCCCGCACTTCCAGCATGCTGAAGTCAGGA
  TCCTGCAGGCCCAGGTGCCTCCTGTGTTCCTCCAACAGCAGCAGCAGTACCAGTACCTGCAGCAATCTCA
  GGAGCACCCCCCTCCCCCACATCCAGCTGCTCTCGGCCATGGCCCCCTGAGCTCCCTCAGTCCACCTGCT
  GTGGAGGGGCCAGTGAGTGCCCAGGCCTCCTCAGCCACCTCGGGCAGTGCCCACCTGGCCCAGATGGAGG
  CCGTGCTGAGGGAGAATGCCAGGCTGCAGAGAGACAATGAGCGGCTGCAGAGGGAGCTGGAGAGCTCTGC
  GGAGAAGGCTGGCCGCATTGAGAAGCTGGAAAGCGAAATCCAGCGGCTCTCTGAGGCCCATGAGAGCCTG
  ACCAGAGCCTCCTCCAAGCGTGAGGCCCTGGAGAAGACCATGCGGAACAAGATGGACAGTGAAATGAGGA
  GGCTGCAAGACTTCAACCGGGATCTTAGAGAGAGATTGGAATCTGCAAATCGCCGCCTGGCAAGCAAGAC
  ACAGGAGGCCCAGGCCGGCAGTCAGGACATGGTGGCCAAGCTGCTTGCTCAGAGCTACGAACAGCAGCAG
  GAGCAAGAGAAGCTGGAGCGAGAGATGGCACTGCTGCGCGGCGCCATCGAGGACCAGCGGCGGCGTGCCG
  AGCTGCTGGAGCAGGCTCTGGGCAATGCGCAGGGCCGGGCAGCTCGAGCCGAAGAGGAGCTGCGCAAGAA
  GCAGGCCTATGTGGAGAAAGTGGAGCGGCTGCAGCAGGCGCTCGGGCAGCTGCAGGCAGCCTGTGAGAAG
  CGGGAGCAGCTGGAGCTGCGTCTGCGGACTCGCCTGGAGCAGGAACTCAAGGCCCTGCGTGCACAGCAGA
  GACAGGCAGGTGCCCCAGGTGGTAGCAGTGGCAGTGGTGGGTCTCCAGAGCTCAGCGCCCTGCGACTGTC
  AGAACAACTGCGAGAGAAGGAGGAGCAGATCCTGGCGCTGGAGGCCGACATGACCAAGTGGGAGCAGAAG
  TATTTGGAGGAACGTGCCATGAGGCAGTTTGCCATGGATGCGGCTGCCACGGCTGCTGCTCAGCGTGACA
  CCACTCTCATCCGACATTCCCCCCAGCCCTCACCCAGCAGCAGCTTCAATGAGGGTCTGCTCACTGGTGG
  CCACAGGCATCAGGAGATGGAAAGCAGGTTAAAGGTGCTCCATGCCCAGATCCTGGAGAAGGATGCAGTG
  ATCAAGGTCCTTCAGCAGCGCTCCAGGAGAGACCCTGGCAAGGCCATCCAGGGCTCCCTGCGGCCTGCCA
  AGTCGGTGCCATCTGTTTTCGCGGCTGCGGCAGCAGGAACCCAGGGCTGGCAAGGGCTCTCTTCTAGTGA
  GCGACAAACAGCAGACGCCCCTGCTCGGCTGACTACAGACAGAGCACCCACAGAGGAGCCAGTGGTCACA
  GCTCCCCCTGCTGCCCATGCCAAACACGGGAGCAGAGATGGGAGCACCCAGACTGAGGGCCCCCCAGACA
  GCACCTCCACCTGCCTGCCACCGGAGCCTGACAGCCTTCTGGGGTGCAGCAGTAGCCAGAGAGCAGCCTC
  TCTGGACTCTGTAGCTACATCCAGAGTCCAGGACTTGTCAGACATGGTGGAGATACTGATC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC239657 representing NM_001278683
  Red=Cloning site Green=Tags(s)
  
  MTGRKASGGTPCTLRKGAPIITLGKNWTERLAAGDSVGCSGARCHRPLSRQLCASQRSMRTLEDSSGTVL
  HRLIQEQLRYGNLTETRTLLAIQQQALRGGAGTGGTGSPQASLEILAPEDSQVLQQATRQEPQGQEHQGG
  ENHLAENTLYRLCPQPSKGEELPTYEEAKAHSQYYAAQQAGTRPHAGDRDPRGAPGGSRRQDEALRELRH
  GHVRSLSERLLQLSLERNGARAPSHMSSSHSFPQLARNQQGPPLRGPPAEGPESRGPPPQYPHVVLAHET
  TTAVTDPRYRARGSPHFQHAEVRILQAQVPPVFLQQQQQYQYLQQSQEHPPPPHPAALGHGPLSSLSPPA
  VEGPVSAQASSATSGSAHLAQMEAVLRENARLQRDNERLQRELESSAEKAGRIEKLESEIQRLSEAHESL
  TRASSKREALEKTMRNKMDSEMRRLQDFNRDLRERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQ
  EQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQAYVEKVERLQQALGQLQAACEK
  REQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLSEQLREKEEQILALEADMTKWEQK
  YLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLTGGHRHQEMESRLKVLHAQILEKDAV
  IKVLQQRSRRDPGKAIQGSLRPAKSVPSVFAAAAAGTQGWQGLSSSERQTADAPARLTTDRAPTEEPVVT
  APPAAHAKHGSRDGSTQTEGPPDSTSTCLPPEPDSLLGCSSSQRAASLDSVATSRVQDLSDMVEILI
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001278683
• ORF Size: 2511 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001278683.1, NP_001265612.1
• RefSeq Size: 4991
• RefSeq ORF: 2514
• Locus ID: 51421
• MW: 92.3 kDa
• Gene Summary: Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motin protein family. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]