MYT1L (NM_001303052) Human Tagged ORF Clone

CAT#: RC240033

MYT1L (myc-DDK-tagged) - Human myelin transcription factor 1-like (MYT1L), transcript variant 1

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: MYT1L
• Synonyms: MRD39; myT1-L; NZF1; ZC2H2C2; ZC2HC4B
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC240033 representing NM_001303052
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGGTGGACACCGAGGAGAAGCGGCATCGCACGCGGTCCAAAGGGGTTCGAGTTCCCGTGGAACCAG
  CCATACAAGAGCTGTTCAGCTGTCCCACCCCTGGCTGTGACGGCAGTGGTCATGTCAGTGGCAAATATGC
  AAGACACAGAAGTGTATATGGTTGTCCCTTGGCGAAAAAAAGAAAAACACAAGATAAACAGCCCCAGGAA
  CCTGCTCCTAAACGAAAGCCATTTGCCGTGAAAGCAGACAGCTCCTCAGTGGATGAGTGTGACGACAGTG
  ATGGGACTGAGGACATGGATGAGAAGGAGGAGGATGAGGGGGAGGAGTACTCCGAGGACAATGATGAGCC
  AGGGGATGAGGACGAGGAGGACGAGGAGGGGGACCGGGAGGAGGAGGAGGAGATCGAGGAGGAGGATGAG
  GACGATGACGAGGATGGAGAAGATGTGGAGGATGAAGAAGAGGAAGAGGAGGAGGAGGAGGAGGAGGAAG
  AGGAAGAAGAAAACGAAGACCATCAAATGAATTGTCACAATACTCGAATAATGCAAGACACAGAAAAGGA
  TGATAACAATAATGACGAATATGACAATTACGATGAACTGGTGGCCAAGTCATTGTTAAACCTCGGCAAA
  ATCGCTGAGGATGCAGCCTACCGGGCCAGGACTGAGTCAGAAATGAACAGCAATACCTCCAATAGTCTGG
  AAGACGATAGTGACAAAAACGAAAACCTGGGTCGGAAAAGTGAGTTGAGTTTAGACTTAGACAGTGATGT
  TGTTAGAGAAACAGTGGACTCCCTTAAACTATTAGCCCAAGGACACGGTGTTGTGCTCTCAGAAAACATG
  AATGACAGAAATTATGCAGACAGCATGTCGCAGCAAGACAGTAGAAATATGAATTACGTCATGTTGGGGA
  AGCCCATGAACAACGGACTCATGGAAAAGATGGTGGAGGAGAGCGATGAGGAGGTGTGTCTGAGCAGTCT
  GGAGTGTTTGAGGAATCAGTGCTTCGACCTGGCCAGGAAGCTCAGTGAGACCAACCCGCAGGAGAGGAAT
  CCGCAGCAGAACATGAACATCCGTCAGCATGTCCGGCCAGAAGAGGACTTCCCCGGAAGGACGCCGGACA
  GAAACTACTCGGACATGCTGAACCTCATGCGGCTGGAGGAGCAGTTGAGCCCCCGGTCGAGAGTGTTTGC
  CAGCTGTGCGAAGGAGGATGGGTGTCATGAGCGGGACGACGATACCACCTCTGTGAACTCGGACAGGTCT
  GAAGAGGTGTTCGACATGACCAAGGGGAACCTGACCCTGCTGGAGAAAGCCATCGCTTTGGAAACGGAAA
  GAGCAAAGGCCATGAGGGAGAAGATGGCCATGGAAGCTGGGAGGAGGGACAATATGAGGTCATATGAGGA
  CCAGTCTCCGAGACAACTTCCCGGGGAGGACAGAAAGCCTAAATCCAGTGACAGCCATGTCAAAAAGCCA
  TACTATGGTAAAGATCCCTCAAGAACAGAAAAGAAAGAGAGCAAGTGTCCAACCCCCGGGTGTGATGGAA
  CCGGCCACGTAACTGGGCTGTACCCACATCACCGCAGCCTGTCCGGATGCCCGCACAAAGATAGGGTCCC
  TCCAGAAATCCTTGCCATGCATGAAAGTGTCCTCAAGTGCCCCACTCCGGGCTGCACGGGGCGCGGGCAT
  GTCAACAGCAACAGGAACTCCCACCGAAGCCTCTCCGGATGCCCGATCGCTGCAGCAGAGAAACTGGCCA
  AGGCACAGGAAAAGCACCAGAGCTGCGACGTGTCCAAGTCCAGCCAGGCCTCGGACCGCGTGCTCAGGCC
  AATGTGCTTTGTGAAGCAGCTGGAGATTCCTCAGTATGGCTACAGAAACAATGTCCCCACAACTACGCCG
  CGTTCCAACCTGGCCAAGGAGCTCGAGAAATATTCCAAGACCTCGTTTGAATACAACAGTTACGACAACC
  ATACTTATGGCAAGCGAGCCATAGCTCCCAAGGTGCAAACCAGGGATATATCCCCCAAAGGATATGATGA
  TGCGAAGCGGTACTGCAAGGACCCCAGCCCCAGCAGCAGCAGCACCAGCAGCTACGCGCCCAGCAGCAGC
  AGCAACCTGAGCTGCGGCGGGGGCAGCAGCGCCAGCAGCACGTGCAGCAAGAGCAGCTTCGACTACACGC
  ACGACATGGAGGCGGCCCACATGGCGGCCACCGCCATCCTCAACCTGTCCACGCGCTGCCGCGAGATGCC
  GCAGAACCTGAGCACCAAGCCGCAGGACCTGTGCGCCACGCGGAACCCTGACATGGAGGTGGATGAGAAC
  GGGACCCTGGACCTCAGCATGAACAAGCAGAGGCCGCGGGACAGCTGCTGCCCCATCCTGACCCCTCTGG
  AGCCCATGTCCCCCCAGCAGCAGGCAGTGATGAACAACCGGTGTTTCCAGCTGGGCGAGGGCGACTGCTG
  GGACTTGCCCGTAGACTACACCAAAATGAAACCCCGGAGGATAGACGAGGACGAGTCCAAAGACATTACT
  CCAGAAGACTTGGACCCATTCCAGGAGGCTCTAGAAGAAAGACGGTATCCCGGGGAGGTGACCATCCCAA
  GTCCCAAACCCAAGTACCCTCAGTGCAAGGAGAGCAAAAAGGACTTAATAACTCTGTCTGGCTGCCCCCT
  GGCGGACAAAAGCATTCGAAGTATGCTGGCCACCAGCTCCCAAGAACTCAAGTGCCCCACGCCTGGCTGT
  GATGGTTCTGGACATATCACCGGCAATTATGCTTCTCATCGGAGCCTTTCAGGTTGCCCAAGAGCAAAGA
  AAAGTGGTATCAGGATAGCACAGAGCAAAGAAGATAAAGAAGATCAAGAACCCATCAGGTGTCCGGTCCC
  CGGGTGCGACGGCCAGGGCCACATCACTGGGAAGTACGCGTCCCATCGCAGCGCCTCCGGGTGCCCCTTG
  GCGGCCAAGAGGCAGAAAGACGGGTACCTGAATGGCTCCCAGTTCTCCTGGAAGTCGGTCAAGACGGAAG
  GCATGTCCTGCCCCACGCCAGGATGCGACGGCTCAGGCCACGTCAGCGGCAGCTTCCTCACACACCGCAG
  CTTGTCAGGATGCCCGAGAGCCACGTCAGCGATGAAGAAGGCAAAGCTTTCTGGAGAGCAGATGCTGACC
  ATCAAACAGCGGGCCAGCAACGGTATAGAAAATGATGAAGAAATCAAACAGTTAGATGAAGAAATCAAGG
  AGCTAAATGAATCCAATTCCCAGATGGAAGCCGATATGATTAAACTCAGAACTCAGATTACCACGATGGA
  GAGCAACCTGAAGACCATCGAAGAGGAGAACAAAGTGATTGAGCAGCAGAACGAGTCTCTCCTCCACGAG
  CTGGCGAACCTGAGCCAGTCTCTGATCCACAGCCTGGCTAACATCCAGCTGCCGCACATGGATCCAATCA
  ATGAACAAAATTTTGATGCTTACGTGACTACTTTGACGGAAATGTATACAAATCAAGATCGTTATCAGAG
  TCCAGAAAATAAAGCCCTACTGGAAAATATAAAGCAGGCTGTGAGAGGAATTCAGGTC
  
  ACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGA
  TTACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC240033 representing NM_001303052
  Red=Cloning site Green=Tags(s)
  
  MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQPQE
  PAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDE
  DDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGK
  IAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENM
  NDRNYADSMSQQDSRNMNYVMLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERN
  PQQNMNIRQHVRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS
  EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKPKSSDSHVKKP
  YYGKDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAMHESVLKCPTPGCTGRGH
  VNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTP
  RSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSS
  SNLSCGGGSSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDEN
  GTLDLSMNKQRPRDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDIT
  PEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGC
  DGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHRSASGCPL
  AAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPRATSAMKKAKLSGEQMLT
  IKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHE
  LANLSQSLIHSLANIQLPHMDPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV
  
  TRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-NotI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001303052
• ORF Size: 3558 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001303052.1, NP_001289981.1
• RefSeq Size: 7198
• RefSeq ORF: 3561
• Locus ID: 23040
• Protein Families: Transcription Factors
• MW: 133.5 kDa
• Gene Summary: This gene encodes a member of the zinc finger superfamily of transcription factors whose expression, thus far, has been found only in neuronal tissues. The encoded protein belongs to a novel class of cystein-cystein-histidine-cystein zinc finger proteins that function in the developing mammalian central nervous system. Forced expression of this gene in combination with the basic helix-loop-helix transcription factor NeuroD1 and the transcription factors POU class 3 homeobox 2 and achaete-scute family basic helix-loop-helix transcription factor 1 can convert fetal and postnatal human fibroblasts into induced neuronal cells, which are able to generate action potentials. Mutations in this gene have been associated with an autosomal dominant form of cognitive disability and with autism spectrum disorder. Alternative splicing results in multiple variants. [provided by RefSeq, Jul 2017]