CRTAP (NM_006371) Human Tagged ORF Clone

CAT#: RG200555

CRTAP (GFP-tagged) - Human cartilage associated protein (CRTAP)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: CRTAP
• Synonyms: CASP; LEPREL3; OI7; P3H5
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG200555 representing NM_006371
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGCCGGGGCGCCGGGGGGCCGCGGCGCTGCTAGCGCTGCTGTGCGTGGCCTGCGCGCTGCGCGCCG
  GGCGCGCCCAATACGAACGCTACAGCTTCCGCAGCTTCCCACGGGACGAGCTGATGCCGCTCGAGTCGGC
  CTACCGGCACGCGCTGGACAAGTACAGCGGCGAGCACTGGGCCGAGAGCGTGGGCTACCTGGAGATCAGC
  CTGCGGCTGCACCGCTTGCTGCGCGACAGCGAGGCCTTCTGCCACCGCAACTGCAGCGCCGCGCCGCAGC
  CCGAGCCCGCCGCCGGCCTCGCCAGCTATCCCGAGCTGCGCCTCTTCGGGGGCCTGCTGCGCCGCGCGCA
  CTGCCTCAAGCGCTGCAAGCAGGGCCTGCCAGCCTTCCGCCAGTCCCAGCCCAGCCGCGATGTGCTGGCG
  GACTTCCAGCGCCGCGAGCCCTACAAGTTCCTGCAGTTCGCTTACTTCAAGGCAAATAATCTCCCCAAAG
  CCATCGCCGCTGCTCACACCTTTCTACTGAAGCATCCTGATGACGAAATGATGAAGAGGAACATGGCATA
  TTATAAGAGCCTGCCTGGTGCCGAGGACTACATTAAAGACCTGGAAACCAAGTCATATGAAAGCCTGTTC
  ATCCGAGCAGTGCGGGCATACAACGGTGAGAACTGGAGAACATCCATCACAGACATGGAGCTGGCCCTTC
  CCGACTTCTTCAAAGCCTTTTACGAGTGTCTCGCAGCCTGCGAGGGTTCCAGGGAGATCAAGGACTTCAA
  GGATTTCTACCTTTCCATAGCAGATCATTATGTAGAAGTTCTGGAATGCAAAATACAGTGTGAAGAGAAC
  CTCACCCCAGTTATAGGAGGCTATCCGGTTGAGAAATTTGTGGCTACCATGTATCATTACTTGCAGTTTG
  CCTATTATAAGTTGAACGACCTGAAGAATGCAGCCCCCTGTGCAGTCAGCTATCTGCTCTTTGATCAGAA
  TGACAAGGTCATGCAGCAGAACCTGGTGTATTACCAGTACCACAGGGACACGTGGGGCCTCTCAGATGAG
  CACTTCCAGCCCAGACCTGAAGCAGTTCAGTTCTTTAATGTGACCACACTCCAGAAGGAGCTGTATGACT
  TTGCTAAGGAAAATATAATGGATGATGATGAGGGAGAAGTTGTGGAATATGTGGATGACCTCTTGGAACT
  GGAGGAGACCAGC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG200555 representing NM_006371
  Red=Cloning site Green=Tags(s)
  
  MEPGRRGAAALLALLCVACALRAGRAQYERYSFRSFPRDELMPLESAYRHALDKYSGEHWAESVGYLEIS
  LRLHRLLRDSEAFCHRNCSAAPQPEPAAGLASYPELRLFGGLLRRAHCLKRCKQGLPAFRQSQPSRDVLA
  DFQRREPYKFLQFAYFKANNLPKAIAAAHTFLLKHPDDEMMKRNMAYYKSLPGAEDYIKDLETKSYESLF
  IRAVRAYNGENWRTSITDMELALPDFFKAFYECLAACEGSREIKDFKDFYLSIADHYVEVLECKIQCEEN
  LTPVIGGYPVEKFVATMYHYLQFAYYKLNDLKNAAPCAVSYLLFDQNDKVMQQNLVYYQYHRDTWGLSDE
  HFQPRPEAVQFFNVTTLQKELYDFAKENIMDDDEGEVVEYVDDLLELEETS
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_006371
• ORF Size: 1203 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006371.3, NP_006362.1
• RefSeq Size: 6622
• RefSeq ORF: 1206
• Locus ID: 10491
• Protein Families: Secreted Protein, Transmembrane
• Gene Summary: The protein encoded by this gene is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli. Defects in this gene are associated with osteogenesis imperfecta, a connective tissue disorder characterized by bone fragility and low bone mass. [provided by RefSeq, Jul 2008]