CUEDC2 (NM_024040) Human Tagged ORF Clone

CAT#: RG200790

CUEDC2 (GFP-tagged) - Human CUE domain containing 2 (CUEDC2)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: CUEDC2
• Synonyms: bA18I14.5; C10orf66
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG200790 representing NM_024040
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGCTGGAGAGGATCGTCAGTGCAGCCCTCCTTGCCTTTGTCCAGACACACCTCCCGGAGGCCGACC
  TCAGTGGCTTGGATGAGGTCATCTTCTCCTATGTGCTTGGGGTCCTGGAGGACCTGGGCCCCTCGGGCCC
  ATCAGAGGAGAACTTCGATATGGAGGCTTTCACTGAGATGATGGAGGCCTATGTGCCTGGCTTCGCCCAC
  ATCCCCAGGGGCACAATAGGGGACATGATGCAGAAGCTCTCAGGGCAGCTGAGCGATGCCAGGAACAAAG
  AGAACCTGCAACCGCAGAGCTCTGGTGTCCAAGGTCAGGTGCCCATCTCCCCAGAGCCCCTGCAGCGGCC
  CGAAATGCTCAAAGAAGAGACTAGGTCTTCGGCTGCTGCTGCTGCAGACACCCAAGATGAGGCAACTGGC
  GCTGAGGAGGAGCTTCTGCCAGGGGTGGATGTACTCCTGGAGGTGTTCCCTACCTGTTCGGTGGAGCAGG
  CCCAGTGGGTGCTGGCCAAAGCTCGGGGGGACTTGGAAGAAGCTGTGCAGATGCTGGTAGAGGGAAAGGA
  AGAGGGGCCTGCAGCCTGGGAGGGCCCCAACCAGGACCTGCCCAGACGCCTCAGAGGCCCCCAAAAGGAT
  GAGCTGAAGTCCTTCATCCTGCAGAAGTACATGATGGTGGATAGCGCA
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG200790 representing NM_024040
  Red=Cloning site Green=Tags(s)
  
  MELERIVSAALLAFVQTHLPEADLSGLDEVIFSYVLGVLEDLGPSGPSEENFDMEAFTEMMEAYVPGFAH
  IPRGTIGDMMQKLSGQLSDARNKENLQPQSSGVQGQVPISPEPLQRPEMLKEETRSSAAAAADTQDEATG
  AEEELLPGVDVLLEVFPTCSVEQAQWVLAKARGDLEEAVQMLVEGKEEGPAAWEGPNQDLPRRLRGPQKD
  ELKSFILQKYMMVDSA
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_024040
• ORF Size: 678 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_024040.2, NP_076945.2
• RefSeq Size: 1203
• RefSeq ORF: 864
• Locus ID: 79004
• Domains: CUE
• Gene Summary: Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism. [UniProtKB/Swiss-Prot Function]