LYL1 (NM_005583) Human Tagged ORF Clone

CAT#: RG201234

LYL1 (GFP-tagged) - Human lymphoblastic leukemia derived sequence 1 (LYL1)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: LYL1
• Synonyms: bHLHa18
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG201234 representing NM_005583
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTGCCCGCCTCAGGCACAGGCAGAGGTGGGCCCCACCATGACTGAGAAGGCAGAGATGGTGTGTGCCC
  CCAGCCCAGCGCCTGCCCCACCCCCTAAGCCTGCCTCGCCTGGGCCCCCGCAGGTGGAGGAGGTGGGCCA
  CCGAGGAGGCTCCTCGCCCCCCAGGCTGCCACCTGGTGTACCAGTGATCAGCCTGGGCCACAGCAGGCCC
  CCAGGGGTAGCCATGCCCACCACAGAGCTGGGCACTCTGCGGCCCCCGCTGCTGCAACTCTCCACCCTGG
  GAACTGCCCCGCCCACTTTGGCCCTGCACTACCACCCTCACCCCTTCCTCAACAGTGTCTACATTGGGCC
  AGCAGGACCTTTTAGCATCTTCCCTAGCAGCCGGTTGAAGCGGAGACCAAGCCACTGTGAGCTGGACCTG
  GCTGAGGGGCACCAGCCCCAGAAGGTGGCCCGGCGCGTGTTCACCAACAGCCGGGAGCGCTGGCGGCAGC
  AGAACGTTAACGGCGCCTTCGCCGAGCTGAGGAAGCTGCTGCCGACGCACCCGCCCGACCGGAAGCTGAG
  CAAGAACGAGGTGCTCCGCCTAGCCATGAAGTACATCGGCTTCCTGGTGCGGCTGCTGCGCGACCAAGCC
  GCAGCTCTGGCCGCAGGCCCCACCCCTCCCGGGCCTCGCAAACGGCCGGTGCACCGGGTCCCAGACGACG
  GCGCCCGCCGGGGATCCGGACGCAGGGCCGAGGCGGCAGCGCGCTCGCAGCCCGCGCCCCCGGCCGACCC
  CGACGGCAGCCCCGGTGGAGCGGCCCGGCCCATCAAGATGGAGCAAACCGCTTTGAGCCCAGAGGTGCGG
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG201234 representing NM_005583
  Red=Cloning site Green=Tags(s)
  
  MCPPQAQAEVGPTMTEKAEMVCAPSPAPAPPPKPASPGPPQVEEVGHRGGSSPPRLPPGVPVISLGHSRP
  PGVAMPTTELGTLRPPLLQLSTLGTAPPTLALHYHPHPFLNSVYIGPAGPFSIFPSSRLKRRPSHCELDL
  AEGHQPQKVARRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLLRDQA
  AALAAGPTPPGPRKRPVHRVPDDGARRGSGRRAEAAARSQPAPPADPDGSPGGAARPIKMEQTALSPEVR
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_005583
• ORF Size: 840 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005583.3, NP_005574.2
• RefSeq Size: 1510
• RefSeq ORF: 843
• Locus ID: 4066
• Domains: HLH
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene represents a basic helix-loop-helix transcription factor. The encoded protein may play roles in blood vessel maturation and hematopoeisis. A translocation between this locus and the T cell receptor beta locus (GeneID 6957) on chromosome 7 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Sep 2010]