PANK3 (NM_024594) Human Tagged ORF Clone

CAT#: RG203696

PANK3 (GFP-tagged) - Human pantothenate kinase 3 (PANK3)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: PANK3
• Synonyms: DKFZp686O22247; FLJ12899; MGC16863
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG203696 representing NM_024594
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAGATCAAAGATGCCAAGAAACCCTCTTTCCCATGGTTTGGCATGGACATTGGGGGAACTCTAGTAA
  AGCTCTCGTACTTTGAACCTATTGATATCACAGCAGAGGAAGAGCAAGAAGAAGTTGAGAGTTTAAAAAG
  TATTCGGAAATATTTGACTTCTAACGTGGCATATGGATCCACCGGCATTCGGGATGTACACCTTGAACTG
  AAAGATTTAACACTTTTTGGCCGAAGAGGGAACTTGCACTTTATCAGGTTTCCAACCCAGGACCTGCCTA
  CTTTTATCCAAATGGGAAGAGATAAAAACTTCTCAACATTGCAGACGGTGCTATGTGCTACAGGAGGTGG
  TGCTTACAAGTTTGAAAAAGATTTTCGCACAATTGGAAACCTCCACCTGCACAAACTGGATGAACTTGAC
  TGCCTTGTAAAGGGCTTGCTGTATATAGACTCTGTCAGTTTCAATGGACAAGCCGAGTGCTATTATTTTG
  CTAATGCCTCAGAACCTGAGCGATGCCAAAAGATGCCTTTTAACCTGGATGATCCCTATCCACTGCTTGT
  AGTGAACATTGGCTCAGGAGTCAGTATTTTAGCAGTCCATTCCAAAGACAACTATAAACGAGTGACTGGG
  ACAAGCCTTGGAGGGGGTACCTTTCTGGGTTTATGCAGTTTATTGACTGGCTGTGAAAGTTTTGAAGAGG
  CTCTTGAAATGGCATCCAAAGGTGATAGCACACAAGCTGACAAGCTGGTCCGTGATATTTATGGAGGAGA
  TTATGAAAGATTTGGTTTGCCAGGTTGGGCTGTAGCATCTAGTTTTGGGAATATGATTTATAAGGAGAAG
  CGAGAATCTGTTAGTAAAGAAGATCTGGCAAGAGCTACTTTAGTTACTATCACCAATAACATTGGTTCTG
  TGGCACGAATGTGTGCTGTTAATGAGAAAATAAACAGAGTTGTCTTTGTTGGAAACTTTTTACGTGTCAA
  TACCCTCTCAATGAAACTTTTGGCATATGCACTGGATTACTGGTCAAAAGGTCAACTAAAAGCATTGTTT
  CTAGAACATGAGGGTTACTTTGGAGCAGTTGGTGCACTTCTTGGGCTGCCAAATTTCAGC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG203696 representing NM_024594
  Red=Cloning site Green=Tags(s)
  
  MKIKDAKKPSFPWFGMDIGGTLVKLSYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGSTGIRDVHLEL
  KDLTLFGRRGNLHFIRFPTQDLPTFIQMGRDKNFSTLQTVLCATGGGAYKFEKDFRTIGNLHLHKLDELD
  CLVKGLLYIDSVSFNGQAECYYFANASEPERCQKMPFNLDDPYPLLVVNIGSGVSILAVHSKDNYKRVTG
  TSLGGGTFLGLCSLLTGCESFEEALEMASKGDSTQADKLVRDIYGGDYERFGLPGWAVASSFGNMIYKEK
  RESVSKEDLARATLVTITNNIGSVARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALF
  LEHEGYFGAVGALLGLPNFS
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_024594
• ORF Size: 1110 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_024594.2, NP_078870.1
• RefSeq Size: 3359
• RefSeq ORF: 1113
• Locus ID: 79646
• Domains: Fumble
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Pantothenate and CoA biosynthesis
• Gene Summary: This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver. [provided by RefSeq, Jul 2008]