KCNE4 (NM_080671) Human Tagged ORF Clone

CAT#: RG204246

KCNE4 (GFP-tagged) - Human potassium voltage-gated channel, Isk-related family, member 4 (KCNE4)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: KCNE4
• Synonyms: MIRP3
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG204246 representing NM_080671
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCTGAAAATGGAGCCTCTGAACAGCACGCACCCCGGCACCGCCGCCTCCAGCAGCCCCCTGGAGTCCC
  GTGCGGCCGGTGGCGGCAGCGGCAATGGCAACGAGTACTTCTACATTCTGGTTGTCATGTCCTTCTACGG
  CATTTTCTTGATCGGAATCATGCTGGGCTACATGAAATCCAAGAGGCGGGAGAAGAAGTCCAGCCTCCTG
  CTGCTGTACAAAGACGAGGAGCGGCTCTGGGGGGAGGCCATGAAGCCGCTGCCCGTGGTGTCGGGCCTGA
  GGTCGGTGCAGGTGCCCCTGATGCTGAACATGCTGCAGGAGAGCGTGGCGCCCGCGCTGTCCTGCACCCT
  CTGTTCCATGGAAGGGGACAGCGTGAGCTCCGAGTCCTCCTCCCCGGACGTGCACCTCACCATTCAGGAG
  GAGGGGGCAGACGAGGAGCTGGAGGAGACCTCGGAGACGCCCCTCAACGAGAGCAGCGAAGGGTCCTCGG
  AGAACATCCATCAGAATTCC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG204246 representing NM_080671
  Red=Cloning site Green=Tags(s)
  
  MLKMEPLNSTHPGTAASSSPLESRAAGGGSGNGNEYFYILVVMSFYGIFLIGIMLGYMKSKRREKKSSLL
  LLYKDEERLWGEAMKPLPVVSGLRSVQVPLMLNMLQESVAPALSCTLCSMEGDSVSSESSSPDVHLTIQE
  EGADEELEETSETPLNESSEGSSENIHQNS
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_080671
• ORF Size: 510 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_080671.1, NP_542402.1
• RefSeq Size: 1204
• RefSeq ORF: 666
• Locus ID: 23704
• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane
• Gene Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the embryo and in adult uterus. [provided by RefSeq, Jul 2008]