DCTN4 (NM_016221) Human Tagged ORF Clone

CAT#: RG205235

DCTN4 (GFP-tagged) - Human dynactin 4 (p62) (DCTN4), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: DCTN4
• Synonyms: DYN4; P62
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG205235 representing NM_016221
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCGTCCTTGCTGCAGTCGGACCGGGTTCTCTATCTAGTCCAGGGAGAAAAGAAGGTTCGGGCCCCGC
  TCTCGCAACTCTACTTCTGCCGCTATTGTAGCGAACTGCGGTCGCTGGAATGTGTGTCTCACGAGGTGGA
  CTCCCATTATTGTCCCAGTTGTTTAGAAAATATGCCATCGGCTGAAGCCAAACTAAAAAAGAATAGATGT
  GCCAATTGTTTTGACTGTCCTGGCTGCATGCACACCCTCTCTACTCGGGCCACGAGCATCTCCACACAGC
  TTACAGATGACCCAGCCAAGACCACCATGAAGAAAGCCTATTACCTGGCATGTGGATTTTGTCGCTGGAC
  GTCTAGAGATGTGGGCATGGCAGACAAATCTGTAGCTAGTGGCGGTTGGCAGGAACCTGAAAATCCTCAC
  ACACAACGGATGAACAAATTGATTGAATATTACCAGCAGCTTGCTCAGAAAGAGAAGGTTGAGCGAGATC
  GCAAGAAACTGGCACGACGTAGAAACTATATGCCTCTGGCTTTTTCGGACAAATATGGTCTTGGAACCAG
  GCTTCAGCGACCACGAGCTGGTGCATCCATCAGTACCCTTGCCGGACTTTCCCTTAAAGAAGGAGAGGAT
  CAGAAAGAGATAAAGATTGAGCCAGCTCAGGCTGTGGATGAAGTGGAACCTCTACCTGAAGACTATTATA
  CAAGACCAGTAAATTTAACAGAGGTAACAACCCTTCAGCAGCGTCTGTTACAGCCTGACTTCCAGCCAGT
  CTGTGCTTCACAGCTCTATCCTCGCCACAAACATCTTCTGATCAAACGGTCCCTGCGCTGCCGTAAATGT
  GAACATAATTTGAGCAAGCCAGAATTTAACCCAACGTCAATCAAATTCAAAATCCAGCTGGTCGCTGTCA
  ATTATATTCCAGAAGTGAGAATCATGTCAATTCCCAACCTTCGCTACATGAAGGAGAGCCAGGTCCTCCT
  GACTCTTACAAATCCAGTTGAGAACCTCACCCATGTGACTCTATTCGAGTGTGAGGAGGGGGACCCTGAT
  GATATCAACAGCACTGCTAAGGTGGTGGTGCCTCCCAAAGAGCTCGTTTTAGCTGGCAAGGATGCAGCAG
  CAGAGTACGATGAGTTGGCAGAACCTCAAGACTTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGC
  CAACAAAGTGGGTATTTTCATCAAAGTTACACCACAGCGTGAGGAGGGTGAAGTGACCGTGTGCTTCAAG
  ATGAAGCATGATTTTAAAAACCTGGCAGCCCCCATTCGCCCCATTGAAGAAAGTGACCAGGGAACAGAAG
  TCATCTGGCTCACCCAGCATGTGGAACTTAGCTTGGGCCCACTTCTTCCT
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG205235 representing NM_016221
  Red=Cloning site Green=Tags(s)
  
  MASLLQSDRVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRC
  ANCFDCPGCMHTLSTRATSISTQLTDDPAKTTMKKAYYLACGFCRWTSRDVGMADKSVASGGWQEPENPH
  TQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSDKYGLGTRLQRPRAGASISTLAGLSLKEGED
  QKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPVCASQLYPRHKHLLIKRSLRCRKC
  EHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPD
  DINSTAKVVVPPKELVLAGKDAAAEYDELAEPQDFQDDPDIIAFRKANKVGIFIKVTPQREEGEVTVCFK
  MKHDFKNLAAPIRPIEESDQGTEVIWLTQHVELSLGPLLP
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_016221
• ORF Size: 1380 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_016221.2, NP_057305.1
• RefSeq Size: 3837
• RefSeq ORF: 1383
• Locus ID: 51164
• Protein Pathways: Huntington's disease
• Gene Summary: Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. [UniProtKB/Swiss-Prot Function]