Cathepsin O (CTSO) (NM_001334) Human Tagged ORF Clone

CAT#: RG208268

CTSO (GFP-tagged) - Human cathepsin O (CTSO)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: CTSO
• Synonyms: CTSO1
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG208268 representing NM_001334
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGACGTGCGGGCGCTGCCGTGGCTGCCGTGGCTGCTGTGGCTGCTGTGCCGGGGCGGCGGCGATGCGG
  ACTCCCGCGCCCCCTTCACCCCGACCTGGCCGCGGAGCCGCGAGCGTGAAGCCGCCGCCTTCCGGGAAAG
  TCTTAATAGACATCGATACTTGAATTCTTTATTTCCCAGTGAAAACTCCACCGCCTTCTATGGAATAAAT
  CAGTTTTCCTATTTGTTTCCTGAAGAGTTTAAAGCCATTTATTTAAGAAGCAAACCTTCCAAGTTTCCCA
  GATACTCAGCAGAAGTACATATGTCCATCCCCAATGTGTCTTTGCCGTTAAGATTTGACTGGAGGGACAA
  GCAGGTTGTGACACAAGTGAGAAACCAGCAGATGTGTGGAGGATGCTGGGCCTTCAGCGTGGTGGGGGCA
  GTGGAATCTGCTTATGCAATAAAGGGGAAGCCCCTGGAAGACCTAAGTGTCCAGCAGGTCATTGACTGTT
  CGTATAATAATTATGGCTGCAATGGAGGCTCTACTCTCAATGCTTTGAACTGGTTAAACAAGATGCAAGT
  AAAACTGGTGAAAGATTCAGAATATCCTTTTAAAGCACAAAATGGTCTGTGCCATTACTTTTCTGGTTCA
  CATTCTGGATTTTCAATCAAAGGTTATTCTGCATATGACTTCAGTGACCAAGAAGATGAAATGGCAAAAG
  CACTTCTTACCTTTGGCCCTTTGGTAGTCATAGTAGATGCAGTGAGCTGGCAAGATTATCTGGGAGGCAT
  TATACAGCATCACTGCTCTAGTGGAGAAGCAAATCATGCAGTTCTCATAACTGGGTTTGATAAAACAGGA
  AGCACTCCATATTGGATTGTGCGGAATTCCTGGGGAAGTTCTTGGGGAGTAGATGGTTATGCCCATGTCA
  AAATGGGAAGTAATGTTTGTGGTATTGCAGATTCCGTTTCTTCTATATTTGTG
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG208268 representing NM_001334
  Red=Cloning site Green=Tags(s)
  
  MDVRALPWLPWLLWLLCRGGGDADSRAPFTPTWPRSREREAAAFRESLNRHRYLNSLFPSENSTAFYGIN
  QFSYLFPEEFKAIYLRSKPSKFPRYSAEVHMSIPNVSLPLRFDWRDKQVVTQVRNQQMCGGCWAFSVVGA
  VESAYAIKGKPLEDLSVQQVIDCSYNNYGCNGGSTLNALNWLNKMQVKLVKDSEYPFKAQNGLCHYFSGS
  HSGFSIKGYSAYDFSDQEDEMAKALLTFGPLVVIVDAVSWQDYLGGIIQHHCSSGEANHAVLITGFDKTG
  STPYWIVRNSWGSSWGVDGYAHVKMGSNVCGIADSVSSIFV
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001334
• ORF Size: 963 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001334.2, NP_001325.1
• RefSeq Size: 2943
• RefSeq ORF: 966
• Locus ID: 1519
• Domains: Pept_C1
• Protein Families: Druggable Genome, Protease
• Protein Pathways: Lysosome
• Gene Summary: The protein encoded by the gene is a cysteine proteinase and a member of the papain superfamily. This proteolytic enzyme is involved in cellular protein degradation and turnover. The recombinant form of this enzyme was shown to degrade synthetic peptides typically used as substrates for cysteine proteinases and its proteolytic activity was abolished by an inhibitor of cyteine proteinase. [provided by RefSeq, Jul 2008]