FTCD (NM_006657) Human Tagged ORF Clone

CAT#: RG208573

FTCD (GFP-tagged) - Human formiminotransferase cyclodeaminase (FTCD), transcript variant B

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: FTCD
• Synonyms: LCHC1
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG208573 representing NM_006657
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTCCCAGCTGGTGGAATGCGTCCCCAACTTTTCGGAGGGGAAGAACCAGGAGGTGATCGACGCCATCT
  CTGGAGCCATCACACAGACCCCGGGCTGCGTGCTGCTGGATGTGGACGCAGGCCCTTCCACCAACCGCAC
  CGTGTACACCTTCGTGGGGCCGCCGGAGTGCGTGGTGGAGGGGGCCCTCAACGCTGCCCGGGTAGCTTCC
  CGACTTATCGACATGAGCAGGCACCAAGGAGAGCACCCCCGCATGGGGGCCCTAGACGTCTGCCCCTTCA
  TCCCCGTGAGGGGCGTCAGCGTGGATGAGTGTGTGCTCTGCGCCCAGGCCTTTGGCCAGAGGCTGGCAGA
  GGAGCTGGACGTGCCAGTTTACCTGTACGGCGAGGCAGCCAGGATGGACAGTCGCCGGACCCTGCCGGCC
  ATCCGGGCCGGGGAGTACGAGGCCCTCCCTAAGAAGCTCCAGCAGGCCGACTGGGCGCCCGACTTTGGTC
  CCAGCTCCTTTGTCCCCAGTTGGGGGGCCACGGCCACGGGGGCGAGGAAGTTCCTCATTGCTTTTAACAT
  CAACCTGCTCGGCACAAAGGAGCAAGCCCACCGCATCGCGCTCAACCTGCGGGAGCAGGGCCGCGGGAAG
  GACCAGCCAGGACGTCTGAAGAAAGTTCAGGGCATTGGCTGGTACCTGGATGAGAAGAACCTGGCTCAGG
  TGTCCACCAATCTTCTGGACTTTGAGGTCACGGCACTGCACACGGTCTACGAGGAGACCTGCCGAGAAGC
  ACAGGAGCTGAGCCTCCCAGTGGTGGGCTCACAGCTGGTGGGCCTGGTGCCCCTGAAGGCTCTGCTGGAT
  GCGGCCGCCTTCTACTGCGAGAAGGAGAACCTCTTCATCCTGGAGGAGGAGCAGCGGATCAGGCTGGTGG
  TGAGCCGGCTGGGCCTGGACTCCCTGTGCCCCTTCAGCCCTAAGGAGCGGATCATCGAGTACCTGGTCCC
  TGAGCGCGGGCCTGAGCGAGGCCTGGGCAGCAAGTCCCTGCGCGCCTTCGTGGGGGAGGTGGGTGCCCGC
  TCTGCGGCCCCCGGGGGCGGCTCGGTGGCGGCGGCCGCTGCGGCCATGGGTGCGGCGCTGGGCTCCATGG
  TGGGCCTCATGACCTACGGGCGGCGCCAATTCCAGTCCCTGGACACGACGATGCGGCGCCTGATCCCGCC
  CTTCCGCGAGGCTTCGGCCAAGCTAACCACGCTGGTGGATGCCGACGCCGAGGCCTTCACCGCCTACCTG
  GAAGCAATGAGGCTCCCCAAGAACACACCTGAGGAAAAGGACAGGCGCACGGCGGCCCTACAGGAGGGTC
  TGAGGCGGGCAGTCTCTGTGCCGCTGACGCTGGCGGAGACGGTGGCCTCGCTGTGGCCGGCGCTGCAGGA
  ACTGGCCCGGTGTGGGAACCTGGCCTGCCGGTCAGACCTCCAGGTGGCGGCCAAAGCCCTGGAGATGGGC
  GTGTTTGGCGCATATTTCAACGTGCTCATCAACCTGAGGGACATCACAGACGAGGCATTTAAGGACCAGA
  TCCACCATCGTGTTTCCAGCCTCCTGCAGGAAGCCAAGACCCAGGCTGCACTGGTGCTGGACTGCTTGGA
  GACCCGGCAGGAG
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG208573 representing NM_006657
  Red=Cloning site Green=Tags(s)
  
  MSQLVECVPNFSEGKNQEVIDAISGAITQTPGCVLLDVDAGPSTNRTVYTFVGPPECVVEGALNAARVAS
  RLIDMSRHQGEHPRMGALDVCPFIPVRGVSVDECVLCAQAFGQRLAEELDVPVYLYGEAARMDSRRTLPA
  IRAGEYEALPKKLQQADWAPDFGPSSFVPSWGATATGARKFLIAFNINLLGTKEQAHRIALNLREQGRGK
  DQPGRLKKVQGIGWYLDEKNLAQVSTNLLDFEVTALHTVYEETCREAQELSLPVVGSQLVGLVPLKALLD
  AAAFYCEKENLFILEEEQRIRLVVSRLGLDSLCPFSPKERIIEYLVPERGPERGLGSKSLRAFVGEVGAR
  SAAPGGGSVAAAAAAMGAALGSMVGLMTYGRRQFQSLDTTMRRLIPPFREASAKLTTLVDADAEAFTAYL
  EAMRLPKNTPEEKDRRTAALQEGLRRAVSVPLTLAETVASLWPALQELARCGNLACRSDLQVAAKALEMG
  VFGAYFNVLINLRDITDEAFKDQIHHRVSSLLQEAKTQAALVLDCLETRQE
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_006657
• ORF Size: 1623 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006657.2, NP_006648.1
• RefSeq Size: 1921
• RefSeq ORF: 1626
• Locus ID: 10841
• Protein Pathways: Histidine metabolism, Metabolic pathways, One carbon pool by folate
• Gene Summary: The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2009]