ACSL6 (NM_001009185) Human Tagged ORF Clone

CAT#: RG211883

ACSL6 (GFP-tagged) - Human acyl-CoA synthetase long-chain family member 6 (ACSL6), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: ACSL6
• Synonyms: ACS2; FACL6; LACS2; LACS5; LACS 6
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG211883 representing NM_001009185
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCTGACCTTCTTCCTCGTGTCGGGGGGCTCCCTCTGGCTATTCGTAGAGTTTGTCCTCTCACTTCTGG
  AGAAGATGCAGACACAGGAGATCCTGAGGATACTGCGACTGCCTGAGCTAGGTGACTTGGGACAGTTTTT
  CCGCAGCCTCTCGGCCACCACCCTCGTGAGTATGGGTGCCCTGGCTGCCATCCTTGCCTACTGGTTCACT
  CACCGGCCAAAGGCCTTGCAGCCGCCATGCAACCTCCTGATGCAGTCAGAAGAAGTAGAGGACAGTGGCG
  GGGCACGGCGATCTGTGATTGGGTCTGGCCCTCAGCTACTTACCCACTACTATGATGATGCCCGGACCAT
  GTACCAGGTGTTCCGCCGTGGGCTTAGCATCTCAGGGAATGGGCCCTGTCTTGGTTTCAGGAAGCCTAAG
  CAGCCTTACCAGTGGCTGTCCTACCAGGAGGTGGCCGACAGGGCTGAATTTCTGGGGTCCGGACTTCTCC
  AGCACAATTGTAAAGCATGCACTGATCAGTTTATTGGTGTTTTTGCACAAAATCGGCCAGAGTGGATCAT
  TGTGGAGCTGGCCTGCTACACATATTCCATGGTGGTGGTCCCGCTCTATGACACCCTGGGCCCTGGGGCT
  ATCCGCTACATCATCAATACAGCGGACATCAGCACCGTGATTGTGGACAAACCTCAGAAGGCTGTGCTTC
  TGCTAGAGCATGTGGAGAGGAAGGAGACTCCAGGCCTCAAGCTGATCATCCTCATGGACCCATTCGAAGA
  AGCCCTGAAAGAGAGAGGGCAGAAGTGCGGGGTGGTCATTAAGTCCATGCAGGCCGTGGAGGACTGTGGC
  CAAGAGAATCACCAGGCTCCTGTGCCCCCGCAGCCTGATGACCTCTCCATTGTGTGTTTCACAAGCGGCA
  CGACAGGGAACCCAAAAGGTGCGATGCTCACCCATGGGAACGTGGTGGCTGATTTCTCAGGCTTTCTGAA
  AGTGACAGAGAAAGTGATCTTTCCGAGACAGGACGATGTGCTCATCTCCTTCCTGCCTCTGGCTCACATG
  TTTGAGAGAGTAATCCAGTCTGTCGTCTATTGCCACGGAGGGCGTGTTGGCTTCTTCCAGGGAGATATCC
  GCCTTCTCTCAGATGACATGAAGGCTCTATGCCCCACCATCTTCCCTGTGGTCCCACGACTGCTGAACCG
  GATGTACGACAAGATCTTCAGCCAGGCAAACACACCATTAAAGCGCTGGCTCCTGGAGTTTGCAGCAAAG
  CGTAAGCAAGCCGAGGTCCGGAGTGGAATCATCAGGAATGATAGTATCTGGGATGAACTCTTCTTTAATA
  AGATTCAGGCCAGTCTTGGTGGGTGTGTGCGGATGATTGTTACTGGAGCAGCCCCAGCATCACCAACAGT
  TCTGGGATTTCTCCGGGCAGCTCTAGGGTGCCAGGTTTATGAAGGTTATGGCCAAACTGAGTGCACAGCT
  GGATGTACCTTCACCACTCCTGGCGACTGGACCTCAGGGCACGTAGGGGCGCCACTTCCCTGCAATCATA
  TCAAGCTCGTTGATGTTGAGGAACTGAACTACTGGGCCTGCAAAGGAGAGGGAGAGATATGTGTGAGAGG
  ACCAAATGTGTTCAAAGGCTACTTGAAAGATCCAGACAGGACGAAGGAGGCCCTGGACAGCGATGGCTGG
  CTTCACACTGGAGACATCGGAAAATGGCTGCCGGCAGGAACTCTTAAAATTATTGATCGGAAAAAGCATA
  TATTTAAACTTGCTCAGGGAGAATATGTTGCACCCGAGAAGATTGAGAACATCTACATCCGGAGCCAACC
  TGTGGCGCAAATCTATGTCCATGGGGACAGCTTAAAGGCCTTTTTGGTAGGCATTGTTGTGCCTGACCCT
  GAAGTTATGCCCTCCTGGGCCCAGAAGAGAGGAATTGAAGGAACATATGCAGATCTCTGCACAAATAAGG
  ATCTGAAGAAAGCCATTTTGGAAGATATGGTGAGGTTAGGAAAAGAAAGTGGACTCCATTCTTTTGAGCA
  GGTTAAAGCCATTCACATCCATTCTGACATGTTCTCAGTTCAAAATGGCTTGCTGACACCAACACTAAAA
  GCTAAGAGACCTGAGCTGAGAGAGTACTTCAAAAAACAAATAGAAGAGCTTTACTCAATCTCCATG
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG211883 representing NM_001009185
  Red=Cloning site Green=Tags(s)
  
  MLTFFLVSGGSLWLFVEFVLSLLEKMQTQEILRILRLPELGDLGQFFRSLSATTLVSMGALAAILAYWFT
  HRPKALQPPCNLLMQSEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPK
  QPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGA
  IRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCG
  QENHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLPLAHM
  FERVIQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAK
  RKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTA
  GCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGW
  LHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDP
  EVMPSWAQKRGIEGTYADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLK
  AKRPELREYFKKQIEELYSISM
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001009185
• ORF Size: 2166 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001009185.1, NP_001009185.1
• RefSeq Size: 3047
• RefSeq ORF: 2169
• Locus ID: 23305
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Adipocytokine signaling pathway, Fatty acid metabolism, Metabolic pathways, PPAR signaling pathway
• Gene Summary: The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011]