TMEM231 (NM_001077418) Human Tagged ORF Clone

CAT#: RG212590

TMEM231 (GFP-tagged) - Human transmembrane protein 231 (TMEM231), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: TMEM231
• Synonyms: ALYE870; JBTS20; MKS11; PRO1886
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG212590 representing NM_001077418
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCGCTCTATGAGCTCTTCTCTCACCCGGTCGAGCGCAGTTACCGCGCGGGGCTCTGCTCCAAAGCCG
  CGCTGTTCCTGCTGCTGGCCGCTGCGCTCACGTACATCCCGCCGCTGCTGGTGGCCTTCCGGAGCCACGG
  GTTTTGGCTGAAGCGGAGCAGCTACGAGGAGCAGCCGACCGTGCGCTTCCAACACCAGGTGCTGCTCGTG
  GCCCTGCTCGGACCCGAAAGCGACGGGTTCCTCGCCTGGAGCACGTTCCCCGCCTTCAACCGGCTGCAAG
  GGGATCGCCTGCGCGTCCCGCTCGTTTCGACTAGAGAAGAAGACAGGAACCAGGATGGGAAGACGGACAT
  GTTACATTTTAAGCTGGAGCTTCCCCTGCAGTCCACGGAGCACGTTCTCGGTGTGCAGCTCATCCTGACT
  TTCTCCTATCGATTACACAGGATGGCGACCCTCGTGATGCAGAGCATGGCGTTTCTCCAGTCCTCCTTTC
  CTGTCCCGGGATCCCAGTTATACGTGAACGGAGACCTGAGGCTGCAGCAGAAGCAGCCGCTGAGCTGTGG
  TGGCCTAGATGCCCGATACAACATATCCGTGATCAACGGGACCAGCCCCTTTGCCTATGACTACGACCTC
  ACCCATATTGTTGCTGCCTACCAGGAGAGGAACGTTACCACCGTCCTGAATGATCCCAACCCCATCTGGC
  TGGTGGGCAGGGCCGCAGATGCTCCATTTGTGATTAATGCTATCATCCGATACCCTGTGGAAGTCATTTC
  TTATCAGCCAGGATTCTGGGAGATGGTAAAGTTCGCCTGGGTGCAGTATGTCAGCATCCTGCTTATCTTC
  CTCTGGGTGTTTGAAAGAATCAAGATCTTCGTGTTTCAGAATCAGGTGGTGACCACCATTCCTGTGACAG
  TGACGCCCCGGGGAGACTTGTGTAAGGAGCACTTATCC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG212590 representing NM_001077418
  Red=Cloning site Green=Tags(s)
  
  MALYELFSHPVERSYRAGLCSKAALFLLLAAALTYIPPLLVAFRSHGFWLKRSSYEEQPTVRFQHQVLLV
  ALLGPESDGFLAWSTFPAFNRLQGDRLRVPLVSTREEDRNQDGKTDMLHFKLELPLQSTEHVLGVQLILT
  FSYRLHRMATLVMQSMAFLQSSFPVPGSQLYVNGDLRLQQKQPLSCGGLDARYNISVINGTSPFAYDYDL
  THIVAAYQERNVTTVLNDPNPIWLVGRAADAPFVINAIIRYPVEVISYQPGFWEMVKFAWVQYVSILLIF
  LWVFERIKIFVFQNQVVTTIPVTVTPRGDLCKEHLS
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001077418
• ORF Size: 948 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001077418.1, NP_001070886.1
• RefSeq Size: 2911
• RefSeq ORF: 951
• Locus ID: 79583
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a transmembrane protein, which is a component of the B9 complex involved in the formation of the diffusion barrier between the cilia and plasma membrane. Mutations in this gene cause Joubert syndrome (JBTS). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013]