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IGF2R (NM_000876) Human Tagged ORF Clone
CAT#: RG215594
- TrueORF®
IGF2R (GFP-tagged) - Human insulin-like growth factor 2 receptor (IGF2R)
"NM_000876" in other vectors (3)
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Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Symbol | IGF2R |
| Synonyms | CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R; MPR1; MPR 300; MPR300; MPRI |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG215594 representing NM_000876
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGGGCCGCCGCCGGCCGGAGCCCCCACCTGGGGCCCGCGCCCGCCCGCCGCCCGCAGCGCTCTCTGC TCCTGCTGCAGCTGCTGCTGCTCGTCGCTGCCCCGGGGTCCACGCAGGCCCAGGCCGCCCCGTTCCCCGA GCTGTGCAGTTATACATGGGAAGCTGTTGATACCAAAAATAATGTACTTTATAAAATCAACATCTGTGGA AGTGTGGATATTGTCCAGTGCGGGCCATCAAGTGCTGTTTGTATGCACGACTTGAAGACACGCACTTATC ATTCAGTGGGTGACTCTGTTTTGAGAAGTGCAACCAGATCTCTCCTGGAATTCAACACAACAGTGAGCTG TGACCAGCAAGGCACAAATCACAGAGTCCAGAGCAGCATTGCCTTCCTGTGTGGGAAAACCCTGGGAACT CCTGAATTTGTAACTGCAACAGAATGTGTGCACTACTTTGAGTGGAGGACCACTGCAGCCTGCAAGAAAG ACATATTTAAAGCAAATAAGGAGGTGCCATGCTATGTGTTTGATGAAGAGTTGAGGAAGCATGATCTCAA TCCTCTGATCAAGCTTAGTGGTGCCTACTTGGTGGATGACTCCGATCCGGACACTTCTCTATTCATCAAT GTTTGTAGAGACATAGACACACTACGAGACCCAGGTTCACAGCTGCGGGCCTGTCCCCCCGGCACTGCCG CCTGCCTGGTAAGAGGACACCAGGCGTTTGATGTTGGCCAGCCCCGGGACGGACTGAAGCTGGTGCGCAA GGACAGGCTTGTCCTGAGTTACGTGAGGGAAGAGGCAGGAAAGCTAGACTTTTGTGATGGTCACAGCCCT GCGGTGACTATTACATTTGTTTGCCCGTCGGAGCGGAGAGAGGGCACCATTCCCAAACTCACAGCTAAAT CCAACTGCCGCTATGAAATTGAGTGGATTACTGAGTATGCCTGCCACAGAGATTACCTGGAAAGTAAAAC TTGTTCTCTGAGCGGCGAGCAGCAGGATGTCTCCATAGACCTCACACCACTTGCCCAGAGCGGAGGTTCA TCCTATATTTCAGATGGAAAAGAATATTTGTTTTATTTGAATGTCTGTGGAGAAACTGAAATACAGTTCT GTAATAAAAAACAAGCTGCAGTTTGCCAAGTGAAAAAGAGCGATACCTCTCAAGTCAAAGCAGCAGGAAG ATACCACAATCAGACCCTCCGATATTCGGATGGAGACCTCACCTTGATATATTTTGGAGGTGATGAATGC AGCTCAGGGTTTCAGCGGATGAGCGTCATAAACTTTGAGTGCAATAAAACCGCAGGTAACGATGGGAAAG GAACTCCTGTATTCACAGGGGAGGTTGACTGCACCTACTTCTTCACATGGGACACGGAATACGCCTGTGT TAAGGAGAAGGAAGACCTCCTCTGCGGTGCCACCGACGGGAAGAAGCGCTATGACCTGTCCGCGCTGGTC CGCCATGCAGAACCAGAGCAGAATTGGGAAGCTGTGGATGGCAGTCAGACGGAAACAGAGAAGAAGCATT TTTTCATTAATATTTGTCACAGAGTGCTGCAGGAAGGCAAGGCACGAGGGTGTCCCGAGGACGCGGCAGT GTGTGCAGTGGATAAAAATGGAAGTAAAAATCTGGGAAAATTTATTTCCTCTCCCATGAAAGAGAAAGGA AACATTCAACTCTCTTATTCAGATGGTGATGATTGTGGTCATGGCAAGAAAATTAAAACTAATATCACAC TTGTATGCAAGCCAGGTGATCTGGAAAGTGCACCAGTGTTGAGAACTTCTGGGGAAGGCGGTTGCTTTTA TGAGTTTGAGTGGCACACAGCTGCGGCCTGTGTGCTGTCTAAGACAGAAGGGGAGAACTGCACGGTCTTT GACTCCCAGGCAGGGTTTTCTTTTGACTTATCACCTCTCACAAAGAAAAATGGTGCCTATAAAGTTGAGA CAAAGAAGTATGACTTTTATATAAATGTGTGTGGCCCGGTGTCTGTGAGCCCCTGTCAGCCAGACTCAGG AGCCTGCCAGGTGGCAAAAAGTGATGAGAAGACTTGGAACTTGGGTCTGAGTAATGCGAAGCTTTCATAT TATGATGGGATGATCCAACTGAACTACAGAGGCGGCACGCCCTATAACAATGAAAGACACACACCGAGAG CTACGCTCATCACCTTTCTCTGTGATCGAGACGCGGGAGTGGGCTTCCCTGAATATCAGGAAGAGGATAA CTCCACCTACAACTTCCGGTGGTACACCAGCTATGCCTGCCCGGAGGAGCCCCTGGAATGCGTAGTGACC GACCCCTCCACGCTGGAGCAGTACGACCTCTCCAGTCTGGCAAAATCTGAAGGTGGCCTTGGAGGAAACT GGTATGCCATGGACAACTCAGGGGAACATGTCACGTGGAGGAAATACTACATTAACGTGTGTCGGCCTCT GAATCCAGTGCCGGGCTGCAACCGATATGCATCGGCTTGCCAGATGAAGTATGAAAAAGATCAGGGCTCC TTCACTGAAGTGGTTTCCATCAGTAACTTGGGAATGGCAAAGACCGGCCCGGTGGTTGAGGACAGCGGCA GCCTCCTTCTGGAATACGTGAATGGGTCGGCCTGCACCACCAGCGATGGCAGACAGACCACATATACCAC GAGGATCCATCTCGTCTGCTCCAGGGGCAGGCTGAACAGCCACCCCATCTTTTCTCTCAACTGGGAGTGT GTGGTCAGTTTCCTGTGGAACACAGAGGCTGCCTGTCCCATTCAGACAACGACGGATACAGACCAGGCTT GCTCTATAAGGGATCCCAACAGTGGATTTGTGTTTAATCTTAATCCGCTAAACAGTTCGCAAGGATATAA CGTCTCTGGCATTGGGAAGATTTTTATGTTTAATGTCTGCGGCACAATGCCTGTCTGTGGGACCATCCTG GGAAAACCTGCTTCTGGCTGTGAGGCAGAAACCCAAACTGAAGAGCTCAAGAATTGGAAGCCAGCAAGGC CAGTCGGAATTGAGAAAAGCCTCCAGCTGTCCACAGAGGGCTTCATCACTCTGACCTACAAAGGGCCTCT CTCTGCCAAAGGTACCGCTGATGCTTTTATCGTCCGCTTTGTTTGCAATGATGATGTTTACTCAGGGCCC CTCAAATTCCTGCATCAAGATATCGACTCTGGGCAAGGGATCCGAAACACTTACTTTGAGTTTGAAACCG CGTTGGCCTGTGTTCCTTCTCCAGTGGACTGCCAAGTCACCGACCTGGCTGTAAATGAGTACGACCTGAC TGGCCTAAGCACAGTCAGGAAACCTTGGACGGCTGTTGACACCTCTGTCGATGGGAGAAAGAGGACTTTC TATTTGAGCGTTTGCAATCCTCTCCCTTACATTCCTGGATGCCAGGGCAGCGCAGTGGGGTCTTGCTTAG TGTCAGAAGGCAATAGCTGGAATCTGGGTGTGGTGCAGATGAGTCCCCAAGCCGCGGCGAATGGATCTTT GAGCATCATGTATGTCAACGGTGACAAGTGTGGGAACCAGCGCTTCTCCACCAGGATCACGTTTGAGTGT GCTCAGATATCGGGCTCACCAGCATTTCAGCTTCAGGATGGTTGTGAGTACGTGTTTATCTGGAGAACTG TGGAAGCCTGTCCCGTTGTCAGAGTGGAAGGGGACAACTGTGAGGTGAAAGACCCAAGGCATGGCAACTT GTATGACCTGAAGCCCCTGGGCCTCAACGACACCATCGTGAGCGCTGGCGAATACACTTATTACTTCCGG GTCTGTGGGAAGCTTTCCTCAGACGTCTGCCCCACAAGTGACAAGTCCAAGGTGGTCTCCTCATGTCAGG AAAAGCGGGAACCGCAGGGATTTCACAAAGTGGCAGGTCTCCTGACTCAGAAGCTAACTTATGAAAATGG CTTGTTAAAAATGAACTTCACGGGGGGGGACACTTGCCATAAGGTTTATCAGCGCTCCACAGCCATCTTC TTCTACTGTGACCGCGGCACCCAGCGGCCAGTATTTCTAAAGGAGACTTCAGATTGTTCCTACTTGTTTG AGTGGCGAACGCAGTATGCCTGCCCACCTTTCGATCTGACTGAATGTTCATTCAAAGATGGGGCTGGCAA CTCCTTCGACCTCTCGTCCCTGTCAAGGTACAGTGACAACTGGGAAGCCATCACTGGGACGGGGGACCCG GAGCACTACCTCATCAATGTCTGCAAGTCTCTGGCCCCGCAGGCTGGCACTGAGCCGTGCCCTCCAGAAG CAGCCGCGTGTCTGCTGGGTGGCTCCAAGCCCGTGAACCTCGGCAGGGTAAGGGACGGACCTCAGTGGAG AGATGGCATAATTGTCCTGAAATACGTTGATGGCGACTTATGTCCAGATGGGATTCGGAAAAAGTCAACC ACCATCCGATTCACCTGCAGCGAGAGCCAAGTGAACTCCAGGCCCATGTTCATCAGCGCCGTGGAGGACT GTGAGTACACCTTTGCCTGGCCCACAGCCACAGCCTGTCCCATGAAGAGCAACGAGCATGATGACTGCCA GGTCACCAACCCAAGCACAGGACACCTGTTTGATCTGAGCTCCTTAAGTGGCAGGGCGGGATTCACAGCT GCTTACAGCGAGAAGGGGTTGGTTTACATGAGCATCTGTGGGGAGAATGAAAACTGCCCTCCTGGCGTGG GGGCCTGCTTTGGACAGACCAGGATTAGCGTGGGCAAGGCCAACAAGAGGCTGAGATACGTGGACCAGGT CCTGCAGCTGGTGTACAAGGATGGGTCCCCTTGTCCCTCCAAATCCGGCCTGAGCTATAAGAGTGTGATC AGTTTCGTGTGCAGGCCTGAGGCCGGGCCAACCAATAGGCCCATGCTCATCTCCCTGGACAAGCAGACAT GCACTCTCTTCTTCTCCTGGCACACGCCGCTGGCCTGCGAGCAAGCGACCGCATGTTCCGTGAGGAATGG AAGCTCTATTGTTGACTTGTCTCCCCTTATTCATCGCACTGGTGGTTATGAGGCTTATGATGAGAGTGAG GATGATGCCTCCGATACCAACCCTGATTTCTACATCAATATTTGTCAGCCACTAAATCCCATGCACGGAG TGCCCTGTCCTGCCGGAGCCGCTGTGTGCAAAGTTCCTATTGATGGTCCCCCCATAGATATCGGCCGGGT AGCAGGACCACCAATACTCAATCCAATAGCAAATGAGATTTACTTGAATTTTGAAAGCAGTACTCCTTGC TTAGCGGACAAGCATTTCAACTACACCTCGCTCATCGCGTTTCACTGTAAGAGAGGTGTGAGCATGGGAA CGCCTAAGCTGTTAAGGACCAGCGAGTGCGACTTTGTGTTCGAATGGGAGACTCCTGTCGTCTGTCCTGA TGAAGTGAGGATGGATGGCTGTACCCTGACAGATGAGCAGCTCCTCTACAGCTTCAACTTGTCCAGCCTT TCCACGAGCACCTTTAAGGTGACTCGCGACTCGCGCACCTACAGCGTTGGGGTGTGCACCTTTGCAGTCG GGCCAGAACAAGGAGGCTGTAAGGACGGAGGAGTCTGTCTGCTCTCAGGCACCAAGGGGGCATCCTTTGG ACGGCTGCAATCAATGAAACTGGATTACAGGCACCAGGATGAAGCGGTCGTTTTAAGTTACGTGAATGGT GATCGTTGCCCTCCAGAAACCGATGACGGCGTCCCCTGTGTCTTCCCCTTCATATTCAATGGGAAGAGCT ACGAGGAGTGCATCATAGAGAGCAGGGCGAAGCTGTGGTGTAGCACAACTGCGGACTACGACAGAGACCA CGAGTGGGGCTTCTGCAGACACTCAAACAGCTACCGGACATCCAGCATCATATTTAAGTGTGATGAAGAT GAGGACATTGGGAGGCCACAAGTCTTCAGTGAAGTGCGTGGGTGTGATGTGACATTTGAGTGGAAAACAA AAGTTGTCTGCCCTCCAAAGAAGTTGGAGTGCAAATTCGTCCAGAAACACAAAACCTACGACCTGCGGCT GCTCTCCTCTCTCACCGGGTCCTGGTCCCTGGTCCACAACGGAGTCTCGTACTATATAAATCTGTGCCAG AAAATATATAAAGGGCCCCTGGGCTGCTCTGAAAGGGCCAGCATTTGCAGAAGGACCACAACTGGTGACG TCCAGGTCCTGGGACTCGTTCACACGCAGAAGCTGGGTGTCATAGGTGACAAAGTTGTTGTCACGTACTC CAAAGGTTATCCGTGTGGTGGAAATAAGACCGCATCCTCCGTGATAGAATTGACCTGTACAAAGACGGTG GGCAGACCTGCATTCAAGAGGTTTGATATCGACAGCTGCACTTACTACTTCAGCTGGGACTCCCGGGCTG CCTGCGCCGTGAAGCCTCAGGAGGTGCAGATGGTGAATGGGACCATCACCAACCCTATAAATGGCAAGAG CTTCAGCCTCGGAGATATTTATTTTAAGCTGTTCAGAGCCTCTGGGGACATGAGGACCAATGGGGACAAC TACCTGTATGAGATCCAACTTTCCTCCATCACAAGCTCCAGAAACCCGGCGTGCTCTGGAGCCAACATAT GCCAGGTGAAGCCCAACGATCAGCACTTCAGTCGGAAAGTTGGAACCTCTGACAAGACCAAGTACTACCT TCAAGACGGCGATCTCGATGTCGTGTTTGCCTCTTCCTCTAAGTGCGGAAAGGATAAGACCAAGTCTGTT TCTTCCACCATCTTCTTCCACTGTGACCCTCTGGTGGAGGACGGGATCCCCGAGTTCAGTCACGAGACTG CCGACTGCCAGTACCTCTTCTCTTGGTACACCTCAGCCGTGTGTCCTCTGGGGGTGGGCTTTGACAGCGA GAATCCCGGGGACGACGGGCAGATGCACAAGGGGCTGTCAGAACGGAGCCAGGCAGTCGGCGCGGTGCTC AGCCTGCTGCTGGTGGCGCTCACCTGCTGCCTGCTGGCCCTGTTGCTCTACAAGAAGGAGAGGAGGGAAA CAGTGATAAGTAAGCTGACCACTTGCTGTAGGAGAAGTTCCAACGTGTCCTACAAATACTCAAAGGTGAA TAAGGAAGAAGAGACAGATGAGAATGAAACAGAGTGGCTGATGGAAGAGATCCAGCTGCCTCCTCCACGG CAGGGAAAGGAAGGGCAGGAGAACGGCCATATTACCACCAAGTCAGTGAAAGCCCTCAGCTCCCTGCATG GGGATGACCAGGACAGTGAGGATGAGGTTCTGACCATCCCAGAGGTGAAAGTTCACTCGGGCAGGGGAGC TGGGGCAGAGAGCTCCCACCCAGTGAGAAACGCACAGAGCAATGCCCTTCAGGAGCGTGAGGACGATAGG GTGGGGCTGGTCAGGGGTGAGAAGGCGAGGAAAGGGAAGTCCAGCTCTGCACAGCAGAAGACAGTGAGCT CCACCAAGCTGGTGTCCTTCCATGACGACAGCGACGAGGACCTCTTACACATC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG215594 representing NM_000876
Red=Cloning site Green=Tags(s) MGAAAGRSPHLGPAPARRPQRSLLLLQLLLLVAAPGSTQAQAAPFPELCSYTWEAVDTKNNVLYKINICG SVDIVQCGPSSAVCMHDLKTRTYHSVGDSVLRSATRSLLEFNTTVSCDQQGTNHRVQSSIAFLCGKTLGT PEFVTATECVHYFEWRTTAACKKDIFKANKEVPCYVFDEELRKHDLNPLIKLSGAYLVDDSDPDTSLFIN VCRDIDTLRDPGSQLRACPPGTAACLVRGHQAFDVGQPRDGLKLVRKDRLVLSYVREEAGKLDFCDGHSP AVTITFVCPSERREGTIPKLTAKSNCRYEIEWITEYACHRDYLESKTCSLSGEQQDVSIDLTPLAQSGGS SYISDGKEYLFYLNVCGETEIQFCNKKQAAVCQVKKSDTSQVKAAGRYHNQTLRYSDGDLTLIYFGGDEC SSGFQRMSVINFECNKTAGNDGKGTPVFTGEVDCTYFFTWDTEYACVKEKEDLLCGATDGKKRYDLSALV RHAEPEQNWEAVDGSQTETEKKHFFINICHRVLQEGKARGCPEDAAVCAVDKNGSKNLGKFISSPMKEKG NIQLSYSDGDDCGHGKKIKTNITLVCKPGDLESAPVLRTSGEGGCFYEFEWHTAAACVLSKTEGENCTVF DSQAGFSFDLSPLTKKNGAYKVETKKYDFYINVCGPVSVSPCQPDSGACQVAKSDEKTWNLGLSNAKLSY YDGMIQLNYRGGTPYNNERHTPRATLITFLCDRDAGVGFPEYQEEDNSTYNFRWYTSYACPEEPLECVVT DPSTLEQYDLSSLAKSEGGLGGNWYAMDNSGEHVTWRKYYINVCRPLNPVPGCNRYASACQMKYEKDQGS FTEVVSISNLGMAKTGPVVEDSGSLLLEYVNGSACTTSDGRQTTYTTRIHLVCSRGRLNSHPIFSLNWEC VVSFLWNTEAACPIQTTTDTDQACSIRDPNSGFVFNLNPLNSSQGYNVSGIGKIFMFNVCGTMPVCGTIL GKPASGCEAETQTEELKNWKPARPVGIEKSLQLSTEGFITLTYKGPLSAKGTADAFIVRFVCNDDVYSGP LKFLHQDIDSGQGIRNTYFEFETALACVPSPVDCQVTDLAVNEYDLTGLSTVRKPWTAVDTSVDGRKRTF YLSVCNPLPYIPGCQGSAVGSCLVSEGNSWNLGVVQMSPQAAANGSLSIMYVNGDKCGNQRFSTRITFEC AQISGSPAFQLQDGCEYVFIWRTVEACPVVRVEGDNCEVKDPRHGNLYDLKPLGLNDTIVSAGEYTYYFR VCGKLSSDVCPTSDKSKVVSSCQEKREPQGFHKVAGLLTQKLTYENGLLKMNFTGGDTCHKVYQRSTAIF FYCDRGTQRPVFLKETSDCSYLFEWRTQYACPPFDLTECSFKDGAGNSFDLSSLSRYSDNWEAITGTGDP EHYLINVCKSLAPQAGTEPCPPEAAACLLGGSKPVNLGRVRDGPQWRDGIIVLKYVDGDLCPDGIRKKST TIRFTCSESQVNSRPMFISAVEDCEYTFAWPTATACPMKSNEHDDCQVTNPSTGHLFDLSSLSGRAGFTA AYSEKGLVYMSICGENENCPPGVGACFGQTRISVGKANKRLRYVDQVLQLVYKDGSPCPSKSGLSYKSVI SFVCRPEAGPTNRPMLISLDKQTCTLFFSWHTPLACEQATACSVRNGSSIVDLSPLIHRTGGYEAYDESE DDASDTNPDFYINICQPLNPMHGVPCPAGAAVCKVPIDGPPIDIGRVAGPPILNPIANEIYLNFESSTPC LADKHFNYTSLIAFHCKRGVSMGTPKLLRTSECDFVFEWETPVVCPDEVRMDGCTLTDEQLLYSFNLSSL STSTFKVTRDSRTYSVGVCTFAVGPEQGGCKDGGVCLLSGTKGASFGRLQSMKLDYRHQDEAVVLSYVNG DRCPPETDDGVPCVFPFIFNGKSYEECIIESRAKLWCSTTADYDRDHEWGFCRHSNSYRTSSIIFKCDED EDIGRPQVFSEVRGCDVTFEWKTKVVCPPKKLECKFVQKHKTYDLRLLSSLTGSWSLVHNGVSYYINLCQ KIYKGPLGCSERASICRRTTTGDVQVLGLVHTQKLGVIGDKVVVTYSKGYPCGGNKTASSVIELTCTKTV GRPAFKRFDIDSCTYYFSWDSRAACAVKPQEVQMVNGTITNPINGKSFSLGDIYFKLFRASGDMRTNGDN YLYEIQLSSITSSRNPACSGANICQVKPNDQHFSRKVGTSDKTKYYLQDGDLDVVFASSSKCGKDKTKSV SSTIFFHCDPLVEDGIPEFSHETADCQYLFSWYTSAVCPLGVGFDSENPGDDGQMHKGLSERSQAVGAVL SLLLVALTCCLLALLLYKKERRETVISKLTTCCRRSSNVSYKYSKVNKEEETDENETEWLMEEIQLPPPR QGKEGQENGHITTKSVKALSSLHGDDQDSEDEVLTIPEVKVHSGRGAGAESSHPVRNAQSNALQEREDDR VGLVRGEKARKGKSSSAQQKTVSSTKLVSFHDDSDEDLLHI TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_000876 |
| ORF Size | 7473 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000876.1, NP_000867.1 |
| RefSeq Size | 9090 bp |
| RefSeq ORF | 7476 bp |
| Locus ID | 3482 |
| Cytogenetics | 6q25.3 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Lysosome |
| Gene Summary | 'This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]' |
Documents
| Product Manuals |
| FAQs |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| SC300143 | IGF2R (untagged)-Human insulin-like growth factor 2 receptor (IGF2R) |
USD 5,050.00 |
|
| RC215594 | IGF2R (Myc-DDK-tagged)-Human insulin-like growth factor 2 receptor (IGF2R) |
USD 1,999.00 |
|
| RC215594L1 | Lenti ORF clone of Human insulin-like growth factor 2 receptor (IGF2R), Myc-DDK-tagged |
USD 2,724.00 |
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