NR3B (GRIN3B) (NM_138690) Human Tagged ORF Clone

CAT#: RG217549

GRIN3B (GFP-tagged) - Human glutamate receptor, ionotropic, N-methyl-D-aspartate 3B (GRIN3B)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: GRIN3B
• Synonyms: GluN3B; NR3B
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG217549 representing NM_138690
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGTTTGTGCGGGCGCTGTGGCTGGGCCTGGCGCTGGCGCTGGGGCCGGGGTCCGCGGGGGGCCACC
  CTCAGCCGTGCGGCGTCCTGGCGCGCCTCGGGGGCTCCGTGCGCCTGGGCGCCCTCCTGCCCCGCGCGCC
  TCTCGCCCGCGCCCGCGCCCGCGCCGCCCTGGCCCGGGCCGCCCTGGCGCCGCGGCTGCCGCACAACCTG
  AGCTTGGAGCTGGTGGTCGCCGCGCCCCCCGCCCGCGACCCCGCCTCGCTGACCCGCGGCCTGTGCCAGG
  CGCTGGTGCCTCCGGGCGTGGCGGCCCTGCTCGCCTTTCCCGAGGCTCGGCCCGAGCTGCTGCAGCTGCA
  CTTCCTGGCGGCGGCCACCGAGACCCCCGTGCTCAGCCTGCTGCGGCGGGAGGCGCGCGCGCCCCTCGGA
  GCCCCGAACCCATTCCACCTGCAGCTGCACTGGGCCAGCCCCCTGGAGACGCTGCTGGATGTGCTGGTGG
  CGGTGCTGCAGGCGCACGCCTGGGAAGACGTCGGCCTGGCCCTGTGCCGCACTCAGGACCCCGGCGGCCT
  GGTGGCCCTCTGGACAAGCCGGGCTGGCCGGCCCCCACAGCTGGTCCTGGACCTAAGCCGGCGGGACACG
  GGAGATGCAGGACTGCGGGCACGCCTGGCCCCGATGGCGGCGCCAGTGGGGGGTGAAGCACCGGTACCCG
  CGGCGGTCCTCCTCGGCTGTGACATCGCCCGTGCCCGTCGGGTGCTGGAGGCCGTACCTCCCGGCCCCCA
  CTGGCTGTTGGGGACACCACTGCCGCCCAAGGCCCTGCCCACCGCGGGGCTGCCACCAGGGCTGCTGGCG
  CTGGGCGAGGTGGCACGACCCCCGCTGGAGGCCGCCATCCATGACATTGTGCAACTGGTGGCCCGGGCGC
  TGGGCAGTGCGGCCCAGGTGCAGCCGAAGCGAGCCCTCCTCCCCGCCCCGGTCAACTGCGGGGACCTGCA
  GCCGGCCGGGCCCGAGTCCCCGGGGCGCTTCTTGGCACGGTTCCTGGCCAACACGTCCTTCCAGGGCCGC
  ACGGGCCCCGTGTGGGTGACAGGCAGCTCCCAGGTACACATGTCTCGGCACTTTAAGGTGTGGAGCCTTC
  GCCGGGACCCACGGGGCGCCCCGGCCTGGGCCACGGTGGGCAGCTGGCGGGACGGCCAGCTGGACTTGGA
  ACCGGGAGGTGCCTCTGCACGGCCCCCGCCCCCACAGGGTGCCCAGGTCTGGCCCAAGCTGCGTGTGGTA
  ACGCTGTTGGAACACCCATTTGTGTTTGCCCGTGATCCAGACGAAGACGGGCAGTGCCCAGCGGGGCAGC
  TGTGCCTGGACCCTGGCACCAACGACTCGGCCACCCTGGACGCACTGTTCGCCGCGCTGGCCAACGGCTC
  AGCGCCCCGTGCCCTGCGCAAGTGCTGCTACGGCTACTGCATTGACCTGCTGGAGCGGCTGGCGGAGGAC
  ACGCCCTTCGACTTCGAGCTGTACCTCGTGGGTGACGGCAAGTACGGCGCCCTGCGGGACGGCCGCTGGA
  CCGGCCTGGTCGGGGACCTGCTGGCCGGCCGGGCCCACATGGCGGTCACCAGCTTCAGTATCAACTCCGC
  CCGCTCACAGGTGGTGGACTTCACCAGCCCCTTCTTCTCCACCAGCCTGGGCATCATGGTGCGGGCACGG
  GACACGGCCTCACCCATCGGTGCCTTTATGTGGCCCCTGCACTGGTCCACGTGGCTGGGCGTCTTTGCGG
  CCCTGCACCTCACCGCGCTCTTCCTCACCGTGTACGAGTGGCGTAGCCCCTACGGCCTCACGCCACGTGG
  CCGCAACCGCAGCACCGTCTTCTCCTACTCCTCAGCCCTCAACCTGTGCTACGCCATCCTCTTCAGACGC
  ACCGTGTCCAGCAAGACGCCCAAGTGCCCCACGGGCCGCCTGCTCATGAACCTCTGGGCCATCTTCTGCC
  TGCTGGTGCTGTCCAGCTACACGGCCAACCTGGCTGCCGTCATGGTCGGGGACAAGACCTTCGAGGAGCT
  GTCGGGGATCCACGACCCCAAGCTGCACCACCCGGCGCAGGGCTTCCGCTTCGGCACCGTGTGGGAGAGC
  AGCGCCGAGGCGTACATCAAGAAGAGCTTCCCCGACATGCACGCACACATGCGGCGCCACAGCGCGCCCA
  CCACGCCCCGCGGCGTCGCCATGCTCACGAGCGACCCCCCCAAGCTCAACGCCTTCATCATGGACAAGTC
  GCTCCTGGACTACGAGGTCTCCATCGACGCCGACTGCAAACTGCTGACCGTGGGAAAGCCCTTCGCCATT
  GAGGGCTATGGGATCGGACTGCCCCAGAACTCGCCGCTCACCTCCAACCTGTCCGAGTTCATCAGCCGCT
  ACAAGTCCTCCGGCTTCATCGACCTGCTCCACGACAAGTGGTACAAGATGGTGCCTTGCGGCAAGCGGGT
  CTTTGCGGTTACAGAGACCCTGCAGATGAGCATCTACCACTTCGCGGGCCTCTTCGTGTTGCTGTGCCTG
  GGCCTGGGCAGCGCTCTGCTCAGCTCGCTGGGCGAGCACGCCTTCTTCCGCCTGGCGCTGCCGCGCATCC
  GCAAGGGGAGCAGGCTGCAGTACTGGCTGCACACCAGCCAGAAAATCCACCGCGCCCTCAACACGGAGCC
  ACCAGAGGGGTCGAAGGAGGAGACGGCAGAGGCGGAGCCCAGCGGCCCCGAGGTGGAGCAGCAGCAGCAG
  CAGCAGGACCAGCCAACGGCTCCGGAGGGCTGGAAACGGGCGCGCCGGGCCGTGGACAAGGAGCGCCGCG
  TGCGCTTCCTGCTGGAGCCCGCCGTGGTTGTGGCACCCGAAGCGGACGCGGAGGCGGAGGCTGCGCCGCG
  AGAGGGCCCCGTCTGGCTGTGCTCCTACGGCCGCCCGCCCGCCGCAAGGCCCACGGGGGCCCCCCAGCCC
  GGGGAGCTGCAGGAGCTGGAGCGCCGCATCGAAGTCGCGCGTGAGCGGCTCCGCCAGGCCCTGGTGCGGC
  GCGGCCAGCTCCTGGCACAGCTCGGGGACAGCGCACGTCACCGGCCTCGGCGCTTGCTTCAGGCCAGAGC
  GGCCCCCGCGGAGGCCCCACCACACTCTGGCCGACCGGGGAGCCAGGAA
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG217549 representing NM_138690
  Red=Cloning site Green=Tags(s)
  
  MEFVRALWLGLALALGPGSAGGHPQPCGVLARLGGSVRLGALLPRAPLARARARAALARAALAPRLPHNL
  SLELVVAAPPARDPASLTRGLCQALVPPGVAALLAFPEARPELLQLHFLAAATETPVLSLLRREARAPLG
  APNPFHLQLHWASPLETLLDVLVAVLQAHAWEDVGLALCRTQDPGGLVALWTSRAGRPPQLVLDLSRRDT
  GDAGLRARLAPMAAPVGGEAPVPAAVLLGCDIARARRVLEAVPPGPHWLLGTPLPPKALPTAGLPPGLLA
  LGEVARPPLEAAIHDIVQLVARALGSAAQVQPKRALLPAPVNCGDLQPAGPESPGRFLARFLANTSFQGR
  TGPVWVTGSSQVHMSRHFKVWSLRRDPRGAPAWATVGSWRDGQLDLEPGGASARPPPPQGAQVWPKLRVV
  TLLEHPFVFARDPDEDGQCPAGQLCLDPGTNDSATLDALFAALANGSAPRALRKCCYGYCIDLLERLAED
  TPFDFELYLVGDGKYGALRDGRWTGLVGDLLAGRAHMAVTSFSINSARSQVVDFTSPFFSTSLGIMVRAR
  DTASPIGAFMWPLHWSTWLGVFAALHLTALFLTVYEWRSPYGLTPRGRNRSTVFSYSSALNLCYAILFRR
  TVSSKTPKCPTGRLLMNLWAIFCLLVLSSYTANLAAVMVGDKTFEELSGIHDPKLHHPAQGFRFGTVWES
  SAEAYIKKSFPDMHAHMRRHSAPTTPRGVAMLTSDPPKLNAFIMDKSLLDYEVSIDADCKLLTVGKPFAI
  EGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDKWYKMVPCGKRVFAVTETLQMSIYHFAGLFVLLCL
  GLGSALLSSLGEHAFFRLALPRIRKGSRLQYWLHTSQKIHRALNTEPPEGSKEETAEAEPSGPEVEQQQQ
  QQDQPTAPEGWKRARRAVDKERRVRFLLEPAVVVAPEADAEAEAAPREGPVWLCSYGRPPAARPTGAPQP
  GELQELERRIEVARERLRQALVRRGQLLAQLGDSARHRPRRLLQARAAPAEAPPHSGRPGSQE
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_138690
• ORF Size: 3129 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_138690.1, NP_619635.1
• RefSeq Size: 3270
• RefSeq ORF: 3132
• Locus ID: 116444
• Protein Families: Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• Gene Summary: The protein encoded by this gene is a subunit of an N-methyl-D-aspartate (NMDA) receptor. The encoded protein is found primarily in motor neurons, where it forms a heterotetramer with GRIN1 to create an excitatory glycine receptor. Variations in this gene have been proposed to be linked to schizophrenia. [provided by RefSeq, Nov 2015]