ADAMTS15 (NM_139055) Human Tagged ORF Clone

CAT#: RG217574

ADAMTS15 (GFP-tagged) - Human ADAM metallopeptidase with thrombospondin type 1 motif, 15 (ADAMTS15)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: ADAMTS15
• Synonyms: MGC126403
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG217574 representing NM_139055
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCTTCTGCTGGGCATCCTAACCCTGGCTTTCGCCGGGCGAACCGCTGGAGGCTCTGAGCCAGAGCGGG
  AGGTAGTCGTTCCCATCCGACTGGACCCGGACATTAACGGCCGCCGCTACTACTGGCGGGGTCCCGAGGA
  CTCCGGGGATCAGGGACTCATTTTTCAGATCACAGCATTTCAGGAGGACTTTTACCTACACCTGACGCCG
  GATGCTCAGTTCTTGGCTCCCGCCTTCTCCACTGAGCATCTGGGCGTCCCCCTCCAGGGGCTCACCGGGG
  GCTCTTCAGACCTGCGACGCTGCTTCTATTCTGGGGACGTGAACGCCGAGCCGGACTCGTTCGCTGCTGT
  GAGCCTGTGCGGGGGGCTCCGCGGAGCCTTTGGCTACCGAGGCGCCGAGTATGTCATTAGCCCGCTGCCC
  AATGCTAGCGCGCCGGCGGCGCAGCGCAACAGCCAGGGCGCACACCTTCTCCAGCGCCGGGGTGTTCCGG
  GCGGGCCTTCCGGAGACCCCACCTCTCGCTGCGGGGTGGCCTCGGGCTGGAACCCCGCCATCCTACGGGC
  CCTGGACCCTTACAAGCCGCGGCGGGCGGGCTTCGGGGAGAGTCGTAGCCGGCGCAGGTCTGGGCGCGCC
  AAGCGTTTCGTGTCTATCCCGCGGTACGTGGAGACGCTGGTGGTCGCGGACGAGTCAATGGTCAAGTTCC
  ACGGCGCGGACCTGGAACATTATCTGCTGACGCTGCTGGCAACGGCGGCGCGACTCTACCGCCATCCCAG
  CATCCTCAACCCCATCAACATCGTTGTGGTCAAGGTGCTGCTTCTTAGAGATCGTGACTCCGGGCCCAAG
  GTCACCGGCAATGCGGCCCTGACGCTGCGCAACTTCTGTGCCTGGCAGAAGAAGCTGAACAAAGTGAGTG
  ACAAGCACCCCGAGTACTGGGACACTGCCATCCTCTTCACCAGGCAGGACCTGTGTGGAGCCACCACCTG
  TGACACCCTGGGCATGGCTGATGTGGGTACCATGTGTGACCCCAAGAGAAGCTGCTCTGTCATTGAGGAC
  GATGGGCTTCCATCAGCCTTCACCACTGCCCACGAGCTGGGCCACGTGTTCAACATGCCCCATGACAATG
  TGAAAGTCTGTGAGGAGGTGTTTGGGAAGCTCCGAGCCAACCACATGATGTCCCCGACCCTCATCCAGAT
  CGACCGTGCCAACCCCTGGTCAGCCTGCAGTGCTGCCATCATCACCGACTTCCTGGACAGCGGGCACGGT
  GACTGCCTCCTGGACCAACCCAGCAAGCCCATCTCCCTGCCCGAGGATCTGCCGGGCGCCAGCTACACCC
  TGAGCCAGCAGTGCGAGCTGGCTTTTGGCGTGGGCTCCAAGCCCTGTCCTTACATGCAGTACTGCACCAA
  GCTGTGGTGCACCGGGAAGGCCAAGGGACAGATGGTGTGCCAGACCCGCCACTTCCCCTGGGCCGATGGC
  ACCAGCTGTGGCGAGGGCAAGCTCTGCCTCAAAGGGGCCTGCGTGGAGAGACACAACCTCAACAAGCACA
  GGGTGGATGGTTCCTGGGCCAAATGGGATCCCTATGGCCCCTGCTCGCGCACATGTGGTGGGGGCGTGCA
  GCTGGCCAGGAGGCAGTGCACCAACCCCACCCCTGCCAACGGGGGCAAGTACTGCGAGGGAGTGAGGGTG
  AAATACCGATCCTGCAATCTGGAGCCCTGCCCCAGCTCAGCCTCCGGAAAGAGCTTCCGGGAGGAGCAGT
  GTGAGGCTTTCAACGGCTACAACCACAGCACCAACCGGCTCACTCTCGCCGTGGCATGGGTGCCCAAGTA
  CTCCGGCGTGTCTCCCCGGGACAAGTGCAAGCTCATCTGCCGAGCCAATGGCACTGGCTACTTCTATGTG
  CTGGCACCCAAGGTGGTGGACGGCACGCTGTGCTCTCCTGACTCCACCTCCGTCTGTGTCCAAGGCAAGT
  GCATCAAGGCTGGCTGTGATGGGAACCTGGGCTCCAAGAAGAGATTCGACAAGTGTGGGGTGTGTGGGGG
  AGACAATAAGAGCTGCAAGAAGGTGACTGGACTCTTCACCAAGCCCATGCATGGCTACAATTTCGTGGTG
  GCCATCCCCGCAGGCGCCTCAAGCATCGACATCCGCCAGCGCGGTTACAAAGGGCTGATCGGGGATGACA
  ACTACCTGGCTCTGAAGAACAGCCAAGGCAAGTACCTGCTCAACGGGCATTTCGTGGTGTCGGCGGTGGA
  GCGGGACCTGGTGGTGAAGGGCAGTCTGCTGCGGTACAGCGGCACGGGCACAGCGGTGGAGAGCCTGCAG
  GCTTCCCGGCCCATCCTGGAGCCGCTGACCGTGGAGGTCCTCTCCGTGGGGAAGATGACACCGCCCCGGG
  TCCGCTACTCCTTCTATCTGCCCAAAGAGCCTCGGGAGGACAAGTCCTCTCATCCCAAGGACCCCCGGGG
  ACCCTCTGTCTTGCACAACAGCGTCCTCAGCCTCTCCAACCAGGTGGAGCAGCCGGACGACAGGCCCCCT
  GCACGCTGGGTGGCTGGCAGCTGGGGGCCGTGCTCCGCGAGCTGCGGCAGTGGCCTGCAGAAGCGGGCGG
  TGGACTGCCGGGGCTCCGCCGGGCAGCGCACGGTCCCTGCCTGTGATGCAGCCCATCGGCCCGTGGAGAC
  ACAAGCCTGCGGGGAGCCCTGCCCCACCTGGGAGCTCAGCGCCTGGTCACCCTGCTCCAAGAGCTGCGGC
  CGGGGATTTCAGAGGCGCTCACTCAAGTGTGTGGGCCACGGAGGCCGGCTGCTGGCCCGGGACCAGTGCA
  ACTTGCACCGCAAGCCCCAGGAGCTGGACTTCTGCGTCCTGAGGCCGTGC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG217574 representing NM_139055
  Red=Cloning site Green=Tags(s)
  
  MLLLGILTLAFAGRTAGGSEPEREVVVPIRLDPDINGRRYYWRGPEDSGDQGLIFQITAFQEDFYLHLTP
  DAQFLAPAFSTEHLGVPLQGLTGGSSDLRRCFYSGDVNAEPDSFAAVSLCGGLRGAFGYRGAEYVISPLP
  NASAPAAQRNSQGAHLLQRRGVPGGPSGDPTSRCGVASGWNPAILRALDPYKPRRAGFGESRSRRRSGRA
  KRFVSIPRYVETLVVADESMVKFHGADLEHYLLTLLATAARLYRHPSILNPINIVVVKVLLLRDRDSGPK
  VTGNAALTLRNFCAWQKKLNKVSDKHPEYWDTAILFTRQDLCGATTCDTLGMADVGTMCDPKRSCSVIED
  DGLPSAFTTAHELGHVFNMPHDNVKVCEEVFGKLRANHMMSPTLIQIDRANPWSACSAAIITDFLDSGHG
  DCLLDQPSKPISLPEDLPGASYTLSQQCELAFGVGSKPCPYMQYCTKLWCTGKAKGQMVCQTRHFPWADG
  TSCGEGKLCLKGACVERHNLNKHRVDGSWAKWDPYGPCSRTCGGGVQLARRQCTNPTPANGGKYCEGVRV
  KYRSCNLEPCPSSASGKSFREEQCEAFNGYNHSTNRLTLAVAWVPKYSGVSPRDKCKLICRANGTGYFYV
  LAPKVVDGTLCSPDSTSVCVQGKCIKAGCDGNLGSKKRFDKCGVCGGDNKSCKKVTGLFTKPMHGYNFVV
  AIPAGASSIDIRQRGYKGLIGDDNYLALKNSQGKYLLNGHFVVSAVERDLVVKGSLLRYSGTGTAVESLQ
  ASRPILEPLTVEVLSVGKMTPPRVRYSFYLPKEPREDKSSHPKDPRGPSVLHNSVLSLSNQVEQPDDRPP
  ARWVAGSWGPCSASCGSGLQKRAVDCRGSAGQRTVPACDAAHRPVETQACGEPCPTWELSAWSPCSKSCG
  RGFQRRSLKCVGHGGRLLARDQCNLHRKPQELDFCVLRPC
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_139055
• ORF Size: 2850 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_139055.1, NP_620686.1
• RefSeq Size: 2853
• RefSeq ORF: 2853
• Locus ID: 170689
• Protein Families: Druggable Genome, Protease, Secreted Protein
• Gene Summary: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme, which may play a role in versican processing during skeletal muscle development. This gene may function as a tumor suppressor in colorectal and breast cancers. [provided by RefSeq, May 2016]