Sphingosine 1 phosphate phosphatase 2 (SGPP2) (NM_152386) Human Tagged ORF Clone

CAT#: RG217993

SGPP2 (GFP-tagged) - Human sphingosine-1-phosphate phosphatase 2 (SGPP2)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: SGPP2
• Synonyms: SPP2; SPPase2
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG217993 representing NM_152386
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCCGAGCTGCTGCGGAGCCTGCAGGATTCCCAGCTCGTCGCCCGCTTCCAGCGCCGCTGCGGGCTCT
  TCCCCGCTCCGGATGAAGGCCCCCGGGAGAACGGCGCGGACCCCACGGAGCGCGCGGCGCGGGTCCCCGG
  GGTCGAGCATCTCCCCGCAGCCAACGGCAAGGGCGGCGAGGCTCCGGCCAACGGGCTGCGCAGAGCCGCG
  GCGCCGGAGGCTTATGTACAGAAGTACGTCGTGAAGAATTATTTCTACTATTACCTATTCCAATTTTCAG
  CTGCTTTGGGCCAAGAAGTGTTCTACATCACGTTTCTTCCATTCACTCACTGGAATATTGACCCTTATTT
  ATCCAGAAGATTGATCATCATATGGGTTTTGGTGATGTATATTGGCCAAGTGGCCAAGGATGTCTTGAAG
  TGGCCCCGTCCCTCCTCCCCTCCAGTTGTAAAACTGGAAAAGAGACTGATCGCTGAATATGGAATGCCAT
  CCACCCACGCCATGGCGGCCACTGCCATTGCCTTCACCCTCCTTATCTCTACTATGGACAGATACCAGTA
  TCCATTTGTGTTGGGACTGGTGATGGCCGTGGTGTTTTCCACCTTGGTGTGTCTCAGCAGGCTCTACACT
  GGGATGCATACGGTCCTGGATGTGCTGGGTGGCGTCCTGATCACCGCACTCCTCATCGTCCTCACCTACC
  CTGCCTGGACCTTCATCGACTGCCTGGACTCGGCCAGCCCCCTCTTCCCCGTGTGTGTCATAGTTGTGCC
  ATTCTTCCTGTGTTACAATTACCCTGTTTCTGATTACTACAGCCCAACCCGGGCGGACACCACCACCATT
  CTGGCTGCCGGGGCTGGAGTGACCATAGGATTCTGGATCAACCATTTCTTCCAGCTTGTATCCAAGCCCG
  CTGAATCTCTCCCTGTTATTCAGAACATCCCACCACTCACCACCTACATGTTAGTTTTGGGTCTGACCAA
  ATTTGCAGTGGGAATTGTGTTGATCCTCTTGGTTCGTCAGCTTGTACAAAATCTCTCACTGCAAGTATTA
  TACTCATGGTTCAAGGTGGTCACCAGGAACAAGGAGGCCAGGCGGAGACTGGAGATTGAAGTGCCTTACA
  AGTTTGTTACCTACACATCTGTTGGCATCTGCGCTACAACCTTTGTGCCGATGCTTCACAGGTTTCTGGG
  ATTACCC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG217993 representing NM_152386
  Red=Cloning site Green=Tags(s)
  
  MAELLRSLQDSQLVARFQRRCGLFPAPDEGPRENGADPTERAARVPGVEHLPAANGKGGEAPANGLRRAA
  APEAYVQKYVVKNYFYYYLFQFSAALGQEVFYITFLPFTHWNIDPYLSRRLIIIWVLVMYIGQVAKDVLK
  WPRPSSPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLISTMDRYQYPFVLGLVMAVVFSTLVCLSRLYT
  GMHTVLDVLGGVLITALLIVLTYPAWTFIDCLDSASPLFPVCVIVVPFFLCYNYPVSDYYSPTRADTTTI
  LAAGAGVTIGFWINHFFQLVSKPAESLPVIQNIPPLTTYMLVLGLTKFAVGIVLILLVRQLVQNLSLQVL
  YSWFKVVTRNKEARRRLEIEVPYKFVTYTSVGICATTFVPMLHRFLGLP
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_152386
• ORF Size: 1197 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_152386.2, NP_689599.2
• RefSeq Size: 1200
• RefSeq ORF: 1200
• Locus ID: 130367
• Protein Families: Transmembrane
• Protein Pathways: Sphingolipid metabolism
• Gene Summary: The protein encoded by this gene is a transmembrane protein that degrades the bioactive signaling molecule sphingosine 1-phosphate. The encoded protein is induced during inflammatory responses and has been shown to be downregulated by the microRNA-31 tumor suppressor. Alternative splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2016]