HRH3 (NM_007232) Human Tagged ORF Clone

CAT#: RG218388

HRH3 (GFP-tagged) - Human histamine receptor H3 (HRH3)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: HRH3
• Synonyms: GPCR97; HH3R
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG218388 representing NM_007232
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGCGCGCGCCGCCCGACGGGCCGCTGAACGCTTCGGGGGCGCTGGCGGGCGATGCGGCGGCGGCGG
  GCGGGGCGCGCGGCTTCTCGGCAGCCTGGACCGCGGTGCTGGCCGCGCTCATGGCGCTGCTCATCGTGGC
  CACGGTGCTGGGCAACGCGCTGGTCATGCTCGCCTTCGTGGCCGACTCGAGCCTCCGCACCCAGAACAAC
  TTCTTCCTGCTCAACCTCGCCATCTCCGACTTCCTCGTCGGCGCCTTCTGCATCCCACTGTATGTACCCT
  ACGTGCTGACAGGCCGCTGGACCTTCGGCCGGGGCCTCTGCAAGCTGTGGCTGGTAGTGGACTACCTGCT
  GTGCACCTCCTCTGCCTTCAACATCGTGCTCATCAGCTACGACCGCTTCCTGTCGGTCACCCGAGCGGTC
  TCATACCGGGCCCAGCAGGGTGACACGCGGCGGGCAGTGCGGAAGATGCTGCTGGTGTGGGTGCTGGCCT
  TCCTGCTGTACGGACCAGCCATCCTGAGCTGGGAGTACCTGTCCGGGGGCAGCTCCATCCCCGAGGGCCA
  CTGCTATGCCGAGTTCTTCTACAACTGGTACTTCCTCATCACGGCTTCCACCCTGGAGTTCTTTACGCCC
  TTCCTCAGCGTCACCTTCTTTAACCTCAGCATCTACCTGAACATCCAGAGGCGCACCCGCCTCCGGCTGG
  ATGGGGCTCGAGAGGCAGCCGGCCCCGAGCCCCCTCCCGAGGCCCAGCCCTCACCACCCCCACCGCCTGG
  CTGCTGGGGCTGCTGGCAGAAGGGGCACGGGGAGGCCATGCCGCTGCACAGGTATGGGGTGGGTGAGGCG
  GCCGTAGGCGCTGAGGCCGGGGAGGCGACCCTCGGGGGTGGCGGTGGGGGCGGCTCCGTGGCTTCACCCA
  CCTCCAGCTCCGGCAGCTCCTCGAGGGGCACTGAGAGGCCGCGCTCACTCAAGAGGGGCTCCAAGCCGTC
  GGCGTCCTCGGCCTCGCTGGAGAAGCGCATGAAGATGGTGTCCCAGAGCTTCACCCAGCGCTTTCGGCTG
  TCTCGGGACAGGAAAGTGGCCAAGTCGCTGGCCGTCATCGTGAGCATCTTTGGGCTCTGCTGGGCCCCAT
  ACACGCTGCTGATGATCATCCGGGCCGCCTGCCATGGCCACTGCGTCCCTGACTACTGGTACGAAACCTC
  CTTCTGGCTCCTGTGGGCCAACTCGGCTGTCAACCCTGTCCTCTACCCTCTGTGCCACCACAGCTTCCGC
  CGGGCCTTCACCAAGCTGCTCTGCCCCCAGAAGCTCAAAATCCAGCCCCACAGCTCCCTGGAGCACTGCT
  GGAAG
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG218388 representing NM_007232
  Red=Cloning site Green=Tags(s)
  
  MERAPPDGPLNASGALAGDAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNN
  FFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAV
  SYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTP
  FLSVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEA
  AVGAEAGEATLGGGGGGGSVASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRL
  SRDRKVAKSLAVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFR
  RAFTKLLCPQKLKIQPHSSLEHCWK
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_007232
• ORF Size: 1335 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_007232.1, NP_009163.1
• RefSeq Size: 2699
• RefSeq ORF: 1338
• Locus ID: 11255
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• Gene Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. [provided by RefSeq, Jul 2008]