INPP4A (NM_001566) Human Tagged ORF Clone

CAT#: RG218886

INPP4A (GFP-tagged) - Human inositol polyphosphate-4-phosphatase, type I, 107kDa (INPP4A), transcript variant b

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: INPP4A
• Synonyms: INPP4; TVAS1
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG218886 representing NM_001566
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACAGCAAGAGAGCACAGCCCTCGCCATGGTGCCAGGGCCCGTGCAATGCAGCGGGCTTCCACCATCG
  ACGTGGCGGCCGACATGCTGGGCCTCTCTCTGGCAGGAAATATACAAGACCCAGATGAGCCCATTTTAGA
  ATTTAGCTTAGCTTGCAGTGAGCTGCATACTCCATCGCTAGATCGAAAGCCAAATAGTTTTGTTGCGGTG
  AGTGTCACCACCCCTCCTCAGGCATTCTGGACGAAGCATGCACAGACGGAGATCATTGAGGGAACCAACA
  ATCCTATATTTCTAAGCAGTATTGCCTTCTTTCAAGACTCTCTTATCAATCAGATGACACAAGTCAAACT
  CTCCGTGTATGATGTCAAAGATAGATCTCAGGGAACAATGTATTTACTGGGCTCTGGAACGTTCATTGTC
  AAAGATCTGCTCCAGGACAGGCATCATAGGTTGCATTTAACACTAAGGTCTGCAGAGAGTGACCGTGTAG
  GTAACATCACCGTGATTGGCTGGCAGATGGAGGAGAAGTCAGACCAACGGCCCCCTGTGACCCGGTCTGT
  GGACACTGTCAATGGGAGGATGGTTCTTCCTGTCGATGAGAGCTTGACGGAGGCGTTAGGAATCCGATCC
  AAATACGCTTCATTGCGAAAGGACACTTTGCTGAAATCGGTGTTCGGTGGTGCCATCTGCCGCATGTACC
  GGTTTCCAACCACTGATGGTAACCATTTGCGGATCCTGGAGCAGATGGCAGAGAGCGTGCTCTCCCTGCA
  CGTGCCCCGGCAGTTCGTGAAGCTCCTACTAGAGGAAGATGCAGCCAGAGTGTGTGAGCTGGAGGAGCTG
  GGAGAGCTGTCCCCTTGCTGGGAGAGCCTCCGGCGCCAAATTGTCACCCAGTACCAGACCATCATCCTCA
  CATACCAGGAGAACCTGACCGACCTCCATCAGTACAGAGGGCCCTCGTTTAAAGCAAGCAGTTTGAAAGC
  AGATAAAAAGTTAGAATTTGTTCCCACAAACTTGCACATACAAAGGATGAGAGTTCAAGACGATGGAGGA
  TCAGATCAGAACTACGACATCGTCACCATTGGGGCGCCAGCAGCACACTGCCAAGGTTTTAAGTCAGGAG
  GTCTCCGCAAAAAGCTGCACAAATTTGAAGAGACCAAGAAACATTTTGAGGAGTGTTGTACATCATCTGG
  CTGCCAGTCCATAATCTACATACCCCAGGATGTTGTCAGAGCCAAGGAGATCATCGCCCAGATCAACACC
  CTGAAAACCCAAGTGAGTTACTACGCAGAGCGGCTGTCAAGGGCAGCCAAGGACAGGTCTGCCACTGGCC
  TTGAGAGGACACTCGCCATCTTGGCAGACAAGACACGGCAGCTGGTCACGGTCTGCGACTGCAAGCTCCT
  GGCCAACTCCATCCATGGGCTGAACGCTGCACGGCCTGACTACATTGCCTCCAAGGCCTCTCCCACTTCG
  ACTGAGGAGGAGCAGGTGATGCTTAGAAATGACCAGGACACCCTCATGGCCCGGTGGACAGGGAGAAACA
  GCCGATCTTCCCTGCAGGTGGACTGGCACGAGGAGGAGTGGGAGAAAGTGTGGCTGAACGTGGACAAGAG
  CCTAGAGTGCATCATTCAGCGTGTGGACAAGCTGCTGCAGAAGGAGCGGCTGCATGGCGAGGGCTGTGAG
  GATGTCTTCCCCTGTGCAGGCAGCTGCACCAGCAAGAAAGATTGCAGTCCCCCTCCTGAAGAGTCCAGCC
  CAGGTGAATGGAGTGAGGCCCTTTACCCGCTGCTGACCACTCTCACCGACTGCGTGGCCATGATGAGTGA
  CAAGGCCAAGAAGGCCATGGTATTCCTGCTCATGCAGGACAGCGCGCCCACCATAGCCACCTACCTGAGC
  CTGCAGTACCGCCGTGACGTGGTCTTCTGCCAGACGCTGACCGCCCTCATCTGCGGCTTCATCATTAAGC
  TGAGGAACTGCCTGCATGACGACGGCTTCCTGCGCCAGCTCTACACCATCGGGCTGCTGGCCCAGTTCGA
  GAGCCTGCTGAGCACCTACGGGGAGGAGCTGGCAATGCTGGAGGACATGAGCCTTGGGATCATGGACTTG
  AGGAACGTGACCTTCAAAGTCACTCAGGCCACTTCCAGCGCCTCCGCAGACATGCTGCCCGTCATCACAG
  GAAATCGCGACGGGTTTAACGTGCGGGTCCCTCTGCCGGGCCCGCTGTTTGACGCCTTGCCCCGGGAGAT
  CCAGAGTGGCATGCTGCTGCGAGTGCAGCCCGTCCTCTTCAACGTGGGCATCAATGAGCAGCAGACACTG
  GCCGAGAGGTTTGGCGATACGTCTTTACAAGAAGTCATCAACGTGGAGAGTTTGGTGCGGTTAAATTCCT
  ACTTTGAGCAGTTTAAGGAAGTTTTGCCTGAGGATTGCCTGCCTCGGTCTCGCAGTCAGACGTGCCTGCC
  AGAGCTGCTGCGGTTTCTGGGTCAGAACGTGCATGCCCGGAAGAATAAGAACGTCGACATTCTCTGGCAA
  GCTGCTGAGATCTGCCGCCGCCTTAATGGGGTCCGGTTCACCAGCTGCAAGAGCGCTAAGGACCGTACAG
  CCATGTCGGTGACACTGGAGCAGTGCCTGATCCTGCAACACGAGCATGGCATGGCCCCGCAGGTCTTCAC
  CCAGGCCCTGGAGTGCATGCGCAGCATTGGAACACGGGAGGTAGTCACCCAGAAAAACTTGAGCGGCCTG
  GTGCCCATCCGAGACTTAAGGCTAGACCCCAGCCTCCTCTGTTCCATCCCTTTATTAGCTCTGAGCCCCA
  ATTTACTGATTGTGTGGCTCTTTCTGAGCATAGCATACCTGGTGACCAAATTGCGTTGCAAA
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG218886 representing NM_001566
  Red=Cloning site Green=Tags(s)
  
  MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSLDRKPNSFVAV
  SVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVYDVKDRSQGTMYLLGSGTFIV
  KDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQRPPVTRSVDTVNGRMVLPVDESLTEALGIRS
  KYASLRKDTLLKSVFGGAICRMYRFPTTDGNHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEEL
  GELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGG
  SDQNYDIVTIGAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT
  LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPDYIASKASPTS
  TEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRVDKLLQKERLHGEGCE
  DVFPCAGSCTSKKDCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIATYLS
  LQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDL
  RNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFDALPREIQSGMLLRVQPVLFNVGINEQQTL
  AERFGDTSLQEVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQ
  AAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSIGTREVVTQKNLSGL
  VPIRDLRLDPSLLCSIPLLALSPNLLIVWLFLSIAYLVTKLRCK
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001566
• ORF Size: 2862 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001566.1, NP_001557.1
• RefSeq Size: 3224
• RefSeq ORF: 2865
• Locus ID: 3631
• Protein Families: Transmembrane
• Protein Pathways: Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system
• Gene Summary: This gene encodes an Mg++ independent enzyme that hydrolyzes the 4-position phosphate from the inositol ring of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and inositol 3,4-bisphosphate. Multiple transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Aug 2008]