INPP4B (NM_001101669) Human Tagged ORF Clone

CAT#: RG219612

INPP4B (GFP-tagged) - Human inositol polyphosphate-4-phosphatase, type II, 105kDa (INPP4B), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: INPP4B
• Synonyms: MGC132014
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG219612 representing NM_001101669
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAAATTAAAGAGGAAGGGGCATCAGAAGAAGGGCAGCACTTTCTTCCTACAGCCCAGGCCAATGATC
  CCGGGGACTGTCAGTTCACAAGTATCCAGAAGACTCCAAATGAACCGCAGTTGGAATTCATCCTTGCATG
  CAAGGATCTCGTGGCTCCTGTCCGTGATCGTAAACTGAATACACTGGTGCAGATCTCCGTAATCCACCCC
  GTGGAGCAGAGTCTGACAAGATACTCCAGCACCGAAATTGTGGAGGGAACAAGGGACCCACTGTTTTTGA
  CTGGTGTCACATTCCCATCTGAGTATCCCATCTATGAGGAGACCAAAATAAAACTAACAGTCTATGATGT
  CAAGGATAAGTCTCATGACACCGTTCGAACCAGTGTCCTACCAGAACATAAGGATCCCCCGCCAGAAGTT
  GGGCGAAGTTTCTTGGGCTATGCCAGTTTTAAAGTGGGAGAGCTGCTGAAGTCAAAGGAGCAATTGCTGG
  TCCTGAGCCTGAGAACTTCAGATGGTGGCAAAGTGGTTGGCACCATAGAAGTCAGTGTCGTGAAGATGGG
  GGAGATTGAGGATGGGGAAGCCGACCACATCACCACAGATGTACAGGGACAAAAGTGTGCCCTGGTATGT
  GAATGTACAGCCCCGGAAAGTGTGAGCGGAAAAGATAACTTACCTTTTTTGAATTCAGTGTTAAAGAACC
  CAGTATGTAAATTATATAGATTTCCCACATCTGACAATAAGTGGATGCGAATTCGAGAGCAGATGTCAGA
  GAGCATTCTTTCCTTTCATATTCCTAAGGAATTGATTTCCCTTCACATTAAAGAAGATTTGTGCAGAAAC
  CAGGAGATAAAAGAACTTGGTGAGCTTTCTCCACATTGGGACAATCTGCGAAAAAATGTCCTTACTCACT
  GTGATCAAATGGTGAATATGTACCAAGACATTCTGACAGAACTTAGCAAGGAAACAGGGTCCTCTTTCAA
  ATCAAGCAGCAGCAAAGGAGAGAAAACATTAGAATTTGTTCCAATAAATCTACATCTGCAAAGAATGCAG
  GTACACAGCCCTCACTTGAAAGATGCTCTCTACGATGTCATCACTGTGGGAGCCCCAGCTGCCCATTTTC
  AGGGATTTAAGAATGGTGGTCTTCGGAAGCTACTCCATAGATTTGAAACAGAAAGAAGAAATACCGGATA
  CCAGTTTATTTACTATTCACCTGAAAACACAGCCAAAGCAAAGGAAGTTCTCAGCAACATCAATCAACTA
  CAACCTCTTATAGCAACCCATGCAGACCTACTGCTTAATTCTGCAAGCCAGCATTCTCCAGACAGCTTGA
  AGAATTCTTTAAAGATGCTTTCAGAAAAAACAGAGCTTTTTGTACATGCCTTCAAGGATCAACTTGTCAG
  GAGTGCTCTTTTAGCACTCTACACTGCAAGGCCAGGAGGCATTCTTAAGAAGCCACCCTCTCCTAAGAGC
  AGCACAGAGGAGAGCAGTCCCCAAGACCAACCCCCAGTGATGAGAGGGCAGGACTCCATACCACATCATT
  CAGACTATGATGAGGAAGAGTGGGACAGGGTGTGGGCCAATGTGGGGAAGAGCCTGAACTGCATTATTGC
  TATGGTGGACAAACTGATTGAAAGAGATGGTGGCAGTGAAGGCAGTGGCGGCAACAATGATGGAGAAAAG
  GAACCTTCATTAACAGATGCCATTCCCTCTCACCCAAGAGAGGACTGGTATGAACAGTTGTATCCCCTCA
  TCCTTACCCTGAAGGACTGCATGGGAGAAGTGGTGAACCGAGCCAAGCAGTCCCTGACATTTGTGCTCCT
  TCAGGAACTTGCGTACAGCTTGCCCCAGTGTCTGATGCTGACGCTAAGAAGAGACATCGTCTTCAGCCAA
  GCACTTGCTGGATTGGTTTGTGGTTTTATCATCAAATTACAGACAAGTCTGTATGACCCAGGCTTCCTAC
  AGCAGCTTCACACAGTGGGGTTGATAGTACAATATGAAGGACTGCTAAGTACATACAGCGATGAAATTGG
  AATGCTAGAGGACATGGCCGTTGGCATTTCCGATTTAAAGAAAGTTGCATTTAAAATAATTGAAGCCAAA
  TCCAATGATGTGTTGCCAGTTATAACAGGAAGACGAGAACATTACGTGGTAGAGGTCAAGCTTCCAGCCA
  GAATGTTTGAGTCACTACCTCTACAGATTAAAGAAGGACAGTTGCTTCATGTGTATCCAGTACTTTTTAA
  TGTTGGAATCAATGAACAGCAAACTCTGGCTGAAAGGTTTGGAGATGTCTCTTTGCAAGAAAGTATTAAT
  CAGGAAAACTTCGAACTTCTACAAGAATATTACAAGATATTTATGGAAAAGATGCCTCCTGATTATATTT
  CACATTTTCAGGAACAAAATGATTTAAAAGCATTGCTAGAAAATCTCCTTCAAAATATCCAATCCAAAAA
  AAGAAAGAATGTAGAAATTATGTGGCTGGCTGCAACGATTTGCCGCAAACTGAATGGTATTCGTTTCACC
  TGTTGTAAAAGTGCCAAAGACAGGACATCGATGTCAGTGACACTTGAACAATGCTCAATCTTGAGAGATG
  AGCACCAGTTACACAAGGACTTCTTTATCCGAGCGCTGGATTGCATGAGAAGAGAAGGATGCCGCATAGA
  GAATGTACTGAAGAATATCAAATGCAGAAAGTATGCTTTCAACATGCTACAGCTGATGGCTTTCCCCAAG
  TACTACAGACCTCCAGAGGGGACTTATGGAAAAGCTGACACC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG219612 representing NM_001101669
  Red=Cloning site Green=Tags(s)
  
  MEIKEEGASEEGQHFLPTAQANDPGDCQFTSIQKTPNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHP
  VEQSLTRYSSTEIVEGTRDPLFLTGVTFPSEYPIYEETKIKLTVYDVKDKSHDTVRTSVLPEHKDPPPEV
  GRSFLGYASFKVGELLKSKEQLLVLSLRTSDGGKVVGTIEVSVVKMGEIEDGEADHITTDVQGQKCALVC
  ECTAPESVSGKDNLPFLNSVLKNPVCKLYRFPTSDNKWMRIREQMSESILSFHIPKELISLHIKEDLCRN
  QEIKELGELSPHWDNLRKNVLTHCDQMVNMYQDILTELSKETGSSFKSSSSKGEKTLEFVPINLHLQRMQ
  VHSPHLKDALYDVITVGAPAAHFQGFKNGGLRKLLHRFETERRNTGYQFIYYSPENTAKAKEVLSNINQL
  QPLIATHADLLLNSASQHSPDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGGILKKPPSPKS
  STEESSPQDQPPVMRGQDSIPHHSDYDEEEWDRVWANVGKSLNCIIAMVDKLIERDGGSEGSGGNNDGEK
  EPSLTDAIPSHPREDWYEQLYPLILTLKDCMGEVVNRAKQSLTFVLLQELAYSLPQCLMLTLRRDIVFSQ
  ALAGLVCGFIIKLQTSLYDPGFLQQLHTVGLIVQYEGLLSTYSDEIGMLEDMAVGISDLKKVAFKIIEAK
  SNDVLPVITGRREHYVVEVKLPARMFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQESIN
  QENFELLQEYYKIFMEKMPPDYISHFQEQNDLKALLENLLQNIQSKKRKNVEIMWLAATICRKLNGIRFT
  CCKSAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRREGCRIENVLKNIKCRKYAFNMLQLMAFPK
  YYRPPEGTYGKADT
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001101669
• ORF Size: 2772 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001101669.1, NP_001095139.1
• RefSeq Size: 4041
• RefSeq ORF: 2775
• Locus ID: 8821
• Protein Families: Druggable Genome
• Protein Pathways: Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system
• Gene Summary: INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme. [provided by RefSeq, Jul 2008]