PXK (NM_017771) Human Tagged ORF Clone

CAT#: RG223483

PXK (GFP-tagged) - Human PX domain containing serine/threonine kinase (PXK)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: PXK
• Synonyms: MONAKA; SLOB
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG223483 representing NM_017771
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCCTTCATGGAGAAGCCGCCAGCCGGCAAGGTGCTGCTGGACGACACGGTGCCGCTGACAGCAGCCA
  TCGAGGCGAGCCAGAGCCTGCAGTCCCACACGGAATATATTATTCGAGTGCAAAGAGGAATTTCTGTGGA
  AAACAGCTGGCAGATTGTTAGAAGATACAGTGACTTTGATTTGCTTAACAACAGCTTACAGATTGCAGGC
  CTAAGTCTACCTCTTCCTCCCAAAAAATTGATTGGTAACATGGATCGTGAATTCATAGCTGAAAGGCAGA
  AAGGTCTTCAGAACTATCTCAACGTGATCACAACAAATCATATCTTGTCTAATTGTGAGCTGGTTAAGAA
  GTTTTTAGATCCAAACAACTATTCCGCAAACTATACTGAGATTGCCTTGCAACAGGTTTCCATGTTCTTC
  CGATCAGAACCAAAGTGGGAGGTGGTGGAACCTTTGAAAGACATAGGTTGGAGAATAAGGAAGAAATATT
  TCTTGATGAAGATTAAAAATCAGCCAAAGGAACGGCTAGTGTTAAGCTGGGCTGACCTTGGCCCAGACAA
  GTATTTGTCAGATAAAGATTTTCAGTGTCTAATCAAACTTCTGCCTTCTTGTTTGCACCCTTACATCTAT
  CGGGTTACCTTTGCCACAGCTAATGAATCCTCAGCGTTGCTAATTAGGATGTTTAACGAAAAGGGAACAT
  TGAAGGATCTGATCTACAAGGCAAAACCAAAAGACCCATTTCTAAAGAAGTACTGCAACCCTAAGAAGAT
  TCAGGGCCTGGAACTCCAGCAAATAAAAACATATGGACGGCAAATATTAGAGGTACTGAAGTTTCTTCAT
  GACAAGGGATTCCCTTATGGGCATCTTCACGCCTCCAATGTGATGCTCGATGGGGACACTTGCCGGCTGC
  TGGACCTTGAGAATTCCTTATTGGGCCTGCCTTCCTTCTACCGATCTTATTTTTCACAATTCAGGAAAAT
  CAATACATTGGAAAGTGTGGATGTCCACTGCTTTGGCCACTTACTGTATGAAATGACTTATGGACGACCG
  CCAGACTCGGTGCCTGTGGACTCCTTCCCTCCTGCCCCGTCCATGGCTGTGGTGGCCGTGTTGGAGTCTA
  CGCTGTCTTGTGAAGCCTGTAAAAATGGCATGCCTACCATCTCCCGGCTCTTACAGATGCCATTATTCAG
  CGATGTTTTACTAACCACTTCTGAAAAACCACAGTTTAAGATCCCTACAAAGTTAAAAGAGGCATTGAGA
  ATTGCCAAAGAATGTATAGAGAAGAGACTAATTGAGGAACAGAAACAGATTCACCAGCATCGAAGACTGA
  CAAGAGCTCAGTCCCACCATGGATCTGAGGAGGAAAGAAAAAAAAGAAAGATTTTAGCTCGAAAGAAGTC
  AAAACGATCTGCTCTTGAAAATAGTGAAGAGCATTCAGCGAAGTACAGCAACTCCAATAATTCAGGATCT
  GGGGCCAGCTCACCTCTCACGTCCCCGTCATCGCCAACTCCACCCTCTACATCAGGGATATCTGCATTAC
  CTCCACCTCCTCCACCTCCACCACCACCAGCAGCTCCCTTGCCTCCTGCGAGCACCGAGGCACCTGCCCA
  GCTCTCGTCTCAGGCTGTGAATGGCATGAGCCGAGGGGCCTTGCTCAGCTCCATCCAGAATTTCCAAAAA
  GGAACTTTGAGGAAAGCCAAAACCTGTGATCACAGTGCTCCGAAGATCGGC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG223483 representing NM_017771
  Red=Cloning site Green=Tags(s)
  
  MAFMEKPPAGKVLLDDTVPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFDLLNNSLQIAG
  LSLPLPPKKLIGNMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFLDPNNYSANYTEIALQQVSMFF
  RSEPKWEVVEPLKDIGWRIRKKYFLMKIKNQPKERLVLSWADLGPDKYLSDKDFQCLIKLLPSCLHPYIY
  RVTFATANESSALLIRMFNEKGTLKDLIYKAKPKDPFLKKYCNPKKIQGLELQQIKTYGRQILEVLKFLH
  DKGFPYGHLHASNVMLDGDTCRLLDLENSLLGLPSFYRSYFSQFRKINTLESVDVHCFGHLLYEMTYGRP
  PDSVPVDSFPPAPSMAVVAVLESTLSCEACKNGMPTISRLLQMPLFSDVLLTTSEKPQFKIPTKLKEALR
  IAKECIEKRLIEEQKQIHQHRRLTRAQSHHGSEEERKKRKILARKKSKRSALENSEEHSAKYSNSNNSGS
  GASSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQLSSQAVNGMSRGALLSSIQNFQK
  GTLRKAKTCDHSAPKIG
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_017771
• ORF Size: 1731 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_017771.2, NP_060241.2
• RefSeq Size: 2050
• RefSeq ORF: 1737
• Locus ID: 54899
• Domains: pkinase, PX
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]