CoREST (RCOR1) (NM_015156) Human Tagged ORF Clone

CAT#: RG224027

RCOR1 (GFP-tagged) - Human REST corepressor 1 (RCOR1)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: RCOR1
• Synonyms: COREST; RCOR
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG224027 representing NM_015156
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGTGGAGAAGGGCCCCGAGGTCTCAGGGAAGCGGAGAGGGAGGAACAACGCGGCCGCCTCCGCCTCCG
  CCGCCGCCGCCTCCGCCGCCGCCTCGGCCGCCTGCGCCTCGCCAGCCGCCACTGCCGCCTCGGGCGCCGC
  CGCCTCCTCAGCCTCGGCCGCCGCCGCCTCAGCCGCCGCCGCCCCCAATAATGGCCAGAATAAAAGTTTG
  GCGGCGGCGGCGCCCAATGGCAACAGCAGCAGCAACTCCTGGGAGGAAGGCAGCTCGGGCTCGTCCAGCG
  ACGAGGAGCACGGTGGCGGTGGCATGAGGGTCGGACCCCAGTACCAGGCGGTGGTGCCCGACTTCGACCC
  CGCCAAACTGGCAAGACGCAGTCAAGAACGGGACAATCTTGGCATGTTGGTCTGGTCACCCAATCAAAAT
  CTGTCAGAAGCAAAGTTGGATGAATACATTGCCATTGCCAAAGAAAAGCATGGGTACAACATGGAACAGG
  CTCTTGGGATGCTCTTCTGGCATAAACATAATATCGAAAAGTCATTGGCTGATTTGCCCAACTTTACCCC
  TTTCCCAGATGAGTGGACTGTGGAAGATAAAGTCTTATTTGAGCAAGCCTTTAGTTTTCATGGGAAAACT
  TTTCATAGAATCCAACAAATGCTTCCAGATAAATCTATAGCAAGTCTGGTGAAATTTTACTATTCTTGGA
  AGAAGACGAGGACTAAAACTAGTGTGATGGATCGCCATGCCCGGAAACAAAAACGGGAGCGGGAGGAGAG
  CGAGGATGAACTGGAAGAGGCAAATGGAAACAATCCCATTGACATTGAGGTTGATCAAAACAAGGAAAGC
  AAAAAGGAGGTTCCCCCTACTGAGACAGTTCCTCAGGTCAAAAAAGAAAAACATAGCACACAAGCTAAAA
  ATAGAGCAAAAAGGAAACCTCCAAAAGGAATGTTTCTTTCTCAAGAAGATGTGGAGGCTGTTTCTGCCAA
  TGCCACTGCTGCTACCACGGTGCTGAGACAACTAGACATGGAATTGGTTTCAGTCAAACGACAGATCCAG
  AATATTAAACAGACAAACAGTGCTCTCAAAGAAAAACTTGATGGTGGAATAGAACCATATCGACTTCCAG
  AGGTCATTCAGAAATGTAATGCACGTTGGACTACAGAAGAGCAGCTTCTCGCCGTACAAGCCATCAGGAA
  ATATGGCCGAGATTTTCAGGCAATCTCAGACGTGATTGGGAACAAATCAGTGGTACAAGTGAAAAACTTT
  TTTGTAAATTATCGACGCCGCTTCAACATAGATGAAGTTTTACAAGAATGGGAGGCAGAACATGGTAAAG
  AAGAGACCAATGGGCCCAGTAACCAGAAGCCTGTGAAGTCCCCAGATAATTCCATTAAGATGCCCGAAGA
  GGAAGACGAGGCTCCTGTTCTGGATGTCAGATATGCATCTGCCTCC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG224027 representing NM_015156
  Red=Cloning site Green=Tags(s)
  
  MVEKGPEVSGKRRGRNNAAASASAAAASAAASAACASPAATAASGAAASSASAAAASAAAAPNNGQNKSL
  AAAAPNGNSSSNSWEEGSSGSSSDEEHGGGGMRVGPQYQAVVPDFDPAKLARRSQERDNLGMLVWSPNQN
  LSEAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKT
  FHRIQQMLPDKSIASLVKFYYSWKKTRTKTSVMDRHARKQKREREESEDELEEANGNNPIDIEVDQNKES
  KKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQ
  NIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNF
  FVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAPVLDVRYASAS
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_015156
• ORF Size: 1455 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_015156.1, NP_055971.1
• RefSeq Size: 1449
• RefSeq ORF: 1458
• Locus ID: 23186
• Domains: ELM2, myb_DNA-binding
• Protein Families: Transcription Factors
• Protein Pathways: Huntington's disease
• Gene Summary: This gene encodes a protein that is well-conserved, downregulated at birth, and with a specific role in determining neural cell differentiation. The encoded protein binds to the C-terminal domain of REST (repressor element-1 silencing transcription factor). [provided by RefSeq, Aug 2011]