STEAP3 (NM_018234) Human Tagged ORF Clone

CAT#: RG224274

STEAP3 (GFP-tagged) - Human STEAP family member 3 (STEAP3), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: STEAP3
• Synonyms: AHMIO2; dudlin-2; dudulin-2; pHyde; STMP3; TSAP6
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG224274 representing NM_018234
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCAGAAGAGATGGACAAGCCACTGATCAGCCTCCACCTGGTGGACAGCGATAGTAGCCTTGCCAAGG
  TCCCCGATGAGGCCCCCAAAGTGGGCATCCTGGGTAGCGGGGACTTTGCCCGCTCCCTGGCCACACGCCT
  GGTGGGCTCTGGCTTCAAAGTGGTGGTGGGGAGCCGCAACCCCAAACGCACAGCCAGGCTGTTTCCCTCA
  GCGGCCCAAGTGACTTTCCAAGAGGAGGCAGTGAGCTCCCCGGAGGTCATCTTTGTGGCTGTGTTCCGGG
  AGCACTACTCTTCACTGTGCAGTCTCAGTGACCAGCTGGCGGGCAAGATCCTGGTGGATGTGAGCAACCC
  TACAGAGCAAGAGCACCTTCAGCATCGTGAGTCCAATGCTGAGTACCTGGCCTCCCTCTTCCCCACTTGC
  ACAGTGGTCAAGGCCTTCAATGTCATCTCTGCCTGGACCCTGCAGGCTGGCCCAAGGGATGGTAACAGGC
  AGGTGCCCATCTGCGGTGACCAGCCAGAAGCCAAGCGTGCTGTCTCGGAGATGGCGCTCGCCATGGGCTT
  CATGCCCGTGGACATGGGATCCCTGGCGTCAGCCTGGGAGGTGGAGGCCATGCCCCTGCGCCTCCTCCCG
  GCCTGGAAGGTGCCCACCCTGCTGGCCCTGGGGCTCTTCGTCTGCTTCTATGCCTACAACTTCGTCCGGG
  ACGTTCTGCAGCCCTATGTGCAGGAAAGCCAGAACAAGTTCTTCAAGCTGCCCGTGTCCGTGGTCAACAC
  CACACTGCCGTGCGTGGCCTACGTGCTGCTGTCACTCGTGTACTTGCCCGGCGTGCTGGCGGCTGCCCTG
  CAGCTGCGGCGCGGCACCAAGTACCAGCGCTTCCCCGACTGGCTGGACCACTGGCTACAGCACCGCAAGC
  AGATCGGGCTGCTCAGCTTCTTCTGCGCCGCCCTGCACGCCCTCTACAGCTTCTGCTTGCCGCTGCGCCG
  CGCCCACCGCTACGACCTGGTCAACCTGGCAGTCAAGCAGGTCTTGGCCAACAAGAGCCACCTCTGGGTG
  GAGGAGGAGGTCTGGCGGATGGAGATCTACCTCTCCCTGGGAGTGCTGGCCCTCGGCACGTTGTCCCTGC
  TGGCCGTGACCTCACTGCCGTCCATTGCAAACTCGCTCAACTGGAGGGAGTTTAGCTTCGTTCAGTCCTC
  ACTGGGCTTTGTGGCCCTCGTGCTGAGCACACTGCACACGCTCACCTACGGCTGGACCCGCGCCTTCGAG
  GAGAGCCGCTACAAGTTCTACCTGCCTCCCACCTTCACGCTCACGCTGCTGGTGCCCTGCGTCGTCATCC
  TGGCCAAAGCCCTGTTTCTCCTGCCCTGCATCAGCCGCAGACTCGCCAGGATCCGGAGAGGCTGGGAGAG
  GGAGAGCACCATCAAGTTCACGCTGCCCACAGACCACGCCCTGGCCGAGAAGACGAGCCACGTA
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG224274 representing NM_018234
  Red=Cloning site Green=Tags(s)
  
  MPEEMDKPLISLHLVDSDSSLAKVPDEAPKVGILGSGDFARSLATRLVGSGFKVVVGSRNPKRTARLFPS
  AAQVTFQEEAVSSPEVIFVAVFREHYSSLCSLSDQLAGKILVDVSNPTEQEHLQHRESNAEYLASLFPTC
  TVVKAFNVISAWTLQAGPRDGNRQVPICGDQPEAKRAVSEMALAMGFMPVDMGSLASAWEVEAMPLRLLP
  AWKVPTLLALGLFVCFYAYNFVRDVLQPYVQESQNKFFKLPVSVVNTTLPCVAYVLLSLVYLPGVLAAAL
  QLRRGTKYQRFPDWLDHWLQHRKQIGLLSFFCAALHALYSFCLPLRRAHRYDLVNLAVKQVLANKSHLWV
  EEEVWRMEIYLSLGVLALGTLSLLAVTSLPSIANSLNWREFSFVQSSLGFVALVLSTLHTLTYGWTRAFE
  ESRYKFYLPPTFTLTLLVPCVVILAKALFLLPCISRRLARIRRGWERESTIKFTLPTDHALAEKTSHV
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_018234
• ORF Size: 1464 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_018234.2, NP_060704.2
• RefSeq Size: 3938
• RefSeq ORF: 1467
• Locus ID: 55240
• Domains: F420_oxidored
• Protein Families: Transmembrane
• Protein Pathways: p53 signaling pathway
• Gene Summary: This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]