UROC1 (NM_001165974) Human Tagged ORF Clone

CAT#: RG228565

UROC1 (GFP-tagged) - Human urocanase domain containing 1 (UROC1), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: UROC1
• Synonyms: HMFN0320; UROCD
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG228565 representing NM_001165974
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTCTAGCCTCCAGGCGCTGTGCTCTGGCCTGCCCCTGCGGCCCCTCCCAGAGAACCGGGGACGCCAGG
  CTGGGGTGCCCCATGCCCCTGTCAGGACCCCCAGCCTCAGCCCTGTGGAGAAACAGCTGGCGCTGAGGAA
  CGCCCTGCGCTACTTCCCCCCGGATGTCCAGGAGCTGCTGGCCCCAGAGTTTGCCCAGGAGCTGCAACTG
  TACGGACACATCTACATGTACCGGTTTTGCCCCGACATTGAAATGAGGGCCTACCCGATTGAGCAGTACC
  CCTGCCAGACGAAAGTGGCTGCCGCCATCATGCACATGATTATGAACAACCTGGATCCTGCCGTGGCCCA
  GTTTCCCCAGGAGCTGGTGACCTATGGAGGAAATGGGCAGGTGTTCAGCAACTGGGCTCAGTTCTGGCTG
  ACCATGTTCTACTTGTCGAAGATGACAGAGGAGCAGACTTTGGTCATGTACAGTGGGCACCCACTTGGCC
  TCTTTCCCAGCAGCCGCAGTGCCCCACGGCTCGTCATCACCAATGGGATGGTCATTCCCAACTACTCCTC
  CCGGACGGAGTATGAGAAGCTCTTTGCCTTGGGGGTTACAATGTACGGCCAGATGACAGCAGGTAGCTAC
  TGCTACATCGGTCCCCAGGGAATCGTTCATGGCACTGTGCTCACCGTGTTGAATGCTGCACGTCGGTACC
  TGGGCATCGAGGACTTGGCTGGGAAGGTCTTTGTCACCTCTGGGCTCGGCGGAATGAGTGGGGCTCAGGC
  CAAGGCCGCAGTCATCGTGGGGTGCATCGGTGTGATAGCAGAGGTGGATAAAGCAGCCCTTGAGAAACGC
  CACAGGCAGGGCTGGCTGATGGAAGTGACTGACAGCTTGGACCGCTGCATCCAGAGGCTCAGGGTCCTTC
  AGCTGGGATTGCAACAAGCCCTGGGCTGGGCCGGCCTCCCTGCTGCCCTGGGACTGTGTGTCCTTTCCTG
  CTTTGTCAACCTTGCACCCCTGGGGGAGGGGAGGTGCCTGGCTCCCTCGGGCTTCTCCAGGCCACTCCTG
  GGGGCACCTGTTCTGCTTTTGTGTCCTTCCAGGGAAGCAAGGAAAAAAAAGGAGGTGCTCAGCCTTGGTT
  ACCATGGCAACGTGGTGGCTCTTTGGGAGCGCCTGGTCCACGAATTGGACACGACGGGGGAGTGCTTGGT
  GGACCTGGGGTCAGATCAGACATCCTGCCACAACCCGTTCAATGGCGGCTACTACCCTGTGCAGCTCAGC
  TTCACGGAGGCCCAGAGCCTCATGGCCTCCAACCCTGCTGTGTTCAAGGACCTGGTCCAGGAAAGCCTGA
  GGAGGCAAGTCTCAGCCATCAACAGGTTGGCCGAGGAGAAGTTCTTCTTCTGGGACTACGGCAATGCCTT
  CCTCTTGGAGGCCCAGAGAGCAGGAGCGGATGTGGAGAAGAAAGGTGCTGGCAGGACAGAGTTCCGCTAC
  CCTTCCTATGTGCAGCACATCATGGGGGACATATTCTCCCAGGGATTTGGGCCTTTCCGCTGGGTGTGCA
  CATCGGGGGACCCCCAGGACCTGGCGGTCACAGACGAACTGGCCACATCTGTGCTGGAGGAAGCCATTGC
  TGATGGAGTGAAGGTGTCTGTGAAGCTGCAGTACATGGACAACATCCGCTGGATCCGGGAGGCCGCCAGG
  CACCGGCTGGTGGTGGGCTCCCAGGCAAGGATCCTGTACTCAGACCAGAAGGGCCGCGTGGCCATCGCTG
  TGGCCATTAACCAGGCCATCGCCTGCAGGAGGATCAAGGCGCCGGTGGTCCTGAGCCGAGATCACCATGA
  CGTGAGCGGCACCGACAGCCCCTTTAGGGAGACCTCCAACATTTACGACGGCTCTGCCTTCTGTGCAGAC
  ATGGCTGTGCAGAACTTCGTGGGAGATGCCTGTCGCGGAGCCACCTGGGTCGCCCTTCACAACGGAGGGG
  GCGTGGGCTGGGGTGAGGTGATCAACGGGGGATTCGGCCTCGTGCTGGACGGTACCCCGGAGGCCGAGGG
  GAGAGCCAGGCTGATGCTCAGCTGGGATGTCTCCAATGGTGTGGCCCGGCGCTGCTGGTCAGGGAACCAG
  AAGGCCTATGAGATCATCTGCCAGACCATGCAGGAGAACAGCACCTTGGTGGTGACACTGCCTCACAAGG
  TGGAGGACGAGCGGGTGCTCCAGCAGGCCCTGCAGCTC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG228565 representing NM_001165974
  Red=Cloning site Green=Tags(s)
  
  MSSLQALCSGLPLRPLPENRGRQAGVPHAPVRTPSLSPVEKQLALRNALRYFPPDVQELLAPEFAQELQL
  YGHIYMYRFCPDIEMRAYPIEQYPCQTKVAAAIMHMIMNNLDPAVAQFPQELVTYGGNGQVFSNWAQFWL
  TMFYLSKMTEEQTLVMYSGHPLGLFPSSRSAPRLVITNGMVIPNYSSRTEYEKLFALGVTMYGQMTAGSY
  CYIGPQGIVHGTVLTVLNAARRYLGIEDLAGKVFVTSGLGGMSGAQAKAAVIVGCIGVIAEVDKAALEKR
  HRQGWLMEVTDSLDRCIQRLRVLQLGLQQALGWAGLPAALGLCVLSCFVNLAPLGEGRCLAPSGFSRPLL
  GAPVLLLCPSREARKKKEVLSLGYHGNVVALWERLVHELDTTGECLVDLGSDQTSCHNPFNGGYYPVQLS
  FTEAQSLMASNPAVFKDLVQESLRRQVSAINRLAEEKFFFWDYGNAFLLEAQRAGADVEKKGAGRTEFRY
  PSYVQHIMGDIFSQGFGPFRWVCTSGDPQDLAVTDELATSVLEEAIADGVKVSVKLQYMDNIRWIREAAR
  HRLVVGSQARILYSDQKGRVAIAVAINQAIACRRIKAPVVLSRDHHDVSGTDSPFRETSNIYDGSAFCAD
  MAVQNFVGDACRGATWVALHNGGGVGWGEVINGGFGLVLDGTPEAEGRARLMLSWDVSNGVARRCWSGNQ
  KAYEIICQTMQENSTLVVTLPHKVEDERVLQQALQL
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001165974
• ORF Size: 2208 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001165974.1, NP_001159446.1
• RefSeq Size: 3460
• RefSeq ORF: 2211
• Locus ID: 131669
• Protein Pathways: Histidine metabolism, Metabolic pathways
• Gene Summary: This gene encodes an enzyme involved in histidine catabolism, metabolizing urocanic acid to formiminoglutamic acid. The gene product is known to protect the skin from ultra violet rays and is contained in human sweat. Deficiency of this gene product in the liver is an apparent cause of cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]