ELAC2 (NM_001165962) Human Tagged ORF Clone

CAT#: RG228581

ELAC2 (GFP-tagged) - Human elaC homolog 2 (E. coli) (ELAC2), transcript variant 3

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: ELAC2
• Synonyms: COXPD17; ELC2; HPC2
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG228581 representing NM_001165962
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTGGGCGCTTTGCTCGCTGCTGCGGTCCGCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGC
  AGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACCCGCTGCGGCACCTGCGCACGCGAGAGAAGCGCGG
  ACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGGGTAGCCGGGACTCG
  GGCGCCGCGCTCTACGTCTTCTCCGAGTTCAACCGGTATCTCTTCAACTGTGGAGAAGGCGTTCAGAGAC
  TCATGCAGGAGCACAAGTTAAAGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAA
  TGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCTTCCAAAGTGTGTACTTTCTGGA
  CCTCCACAACTGGAAAAATACCTCGAAGCAATCAAAATATTTTCTGGTCCATTGAAAGGAATAGAACTGG
  CTGTGCGGCCCCACTCTGCCCCAGAATACGAGGATGAAACCATGACAGTTTACCAGATCCCCATACACAG
  TGTTAGCCAGAGAAGAGGGGTCAGGGACTCTTCCCTGGTCGTAGCTTTCATCTGTAAGCTTCACTTAAAG
  AGAGGAAACTTCTTGGTGCTCAAAGCAAAGGAGATGGGCCTCCCAGTTGGGACAGCTGCCATCGCTCCCA
  TCATTGCTGCTGTCAAGGACGGGAAAAGCATCACTCATGAAGGAAGAGAGATTTTGGCTGAAGAGCTGTG
  TACTCCTCCAGATCCTGGTGCTGCTTTTGTGGTGGTAGAATGTCCAGATGAAAGCTTCATTCAACCCATC
  TGTGAGAATGCCACCTTTCAGAGGTACCAAGGAAAGGCAGATGCCCCCGTGGCCTTGGTGGTTCACATGG
  CCCCAGCATCTGTGCTTGTGGACAGCAGGTACCAGCAGTGGATGGAGAGGTTTGGGCCTGACACCCAGCA
  CTTGGTCCTGAATGAGAACTGTGCCTCAGTTCACAACCTTCGCAGCCACAAGATTCAAACCCAGCTCAAC
  CTCATCCACCCGGACATCTTCCCCCTGCTCACCAGTTTCCGCTGTAAGAAGGAGGGCCCCACCCTCAGTG
  TGCCCATGGTTCAGGGTGAATGCCTCCTCAAGTACCAGCTCCGTCCCAGGAGGGAGTGGCAGAGGGATGC
  CATTATTACTTGCAATCCTGAGGAATTCATAGTTGAGGCGCTGCAGCTTCCCAACTTCCAGCAGAGCGTG
  CAGGAGTACAGGAGGAGTGCGCAGGACGGCCCAGCCCCAGCAGAGAAAAGAAGTCAGTACCCAGAAATCA
  TCTTCCTTGGAACAGGGTCTGCCATCCCGATGAAGATTCGAAATGTCAGTGCCACACTTGTCAACATAAG
  CCCCGACACGTCTCTGCTACTGGACTGTGGTGAGGGCACATTTGGGCAGCTGTGCCGTCATTACGGAGAC
  CAGGTGGACAGGGTCCTGGGCACCCTGGCTGCTGTGTTTGTGTCCCACCTGCACGCAGATCACCACACGG
  GCTTGCCAAGTATCTTGCTGCAGAGAGAACGCGCCTTGGCATCTTTGGGAAAGCCGCTTCACCCTTTGCT
  GGTGGTTGCCCCCAACCAGCTCAAAGCCTGGCTCCAGCAGTACCACAACCAGTGCCAGGAGGTCCTGCAC
  CACATCAGTATGATTCCTGCCAAATGCCTTCAGGAAGGGGCTGAGATCTCCAGTCCTGCAGTGGAAAGAT
  TGATCAGTTCGCTGTTGCGAACATGTGATTTGGAAGAGTTTCAGACCTGTCTGGTGCGGCACTGCAAGCA
  TGCGTTTGGCTGTGCGCTGGTGCACACCTCTGGCTGGAAAGTGGTCTATTCCGGGGACACCATGCCCTGC
  GAGGCTCTGGTCCGGATGGGGAAAGATGCCACCCTCCTGATACATGAAGCCACCCTGGAAGATGGTTTGG
  AAGAGGAAGCAGTGGAAAAGACACACAGCACAACGTCCCAAGCCATCAGCGTGGGGATGCGGATGAACGC
  GGAGTTCATTATGCTGAACCACTTCAGCCAGCGCTATGCCAAGGTCCCCCTCTTCAGCCCCAACTTCAGC
  GAGAAAGTGGGAGTTGCCTTTGACCACATGAAGGTCTGCTTTGGAGACTTTCCAACAATGCCCAAGCTGA
  TTCCCCCACTGAAAGCCCTGTTTGCTGGCGACATCGAGGAGATGGAGGAGCGCAGGGAGAAGCGGGAGCT
  GCGGCAGGTGCGGGCGGCCCTCCTGTCCAGGGAGCTGGCAGGCGGCCTGGAGGATGGGGAGCCTCAGCAG
  AAGCGGGCCCACACAGAGGAGCCACAGGCCAAGAAGGTCAGAGCCCAG
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG228581 representing NM_001165962
  Red=Cloning site Green=Tags(s)
  
  MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDS
  GAALYVFSEFNRYLFNCGEGVQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSG
  PPQLEKYLEAIKIFSGPLKGIELAVRPHSAPEYEDETMTVYQIPIHSVSQRRGVRDSSLVVAFICKLHLK
  RGNFLVLKAKEMGLPVGTAAIAPIIAAVKDGKSITHEGREILAEELCTPPDPGAAFVVVECPDESFIQPI
  CENATFQRYQGKADAPVALVVHMAPASVLVDSRYQQWMERFGPDTQHLVLNENCASVHNLRSHKIQTQLN
  LIHPDIFPLLTSFRCKKEGPTLSVPMVQGECLLKYQLRPRREWQRDAIITCNPEEFIVEALQLPNFQQSV
  QEYRRSAQDGPAPAEKRSQYPEIIFLGTGSAIPMKIRNVSATLVNISPDTSLLLDCGEGTFGQLCRHYGD
  QVDRVLGTLAAVFVSHLHADHHTGLPSILLQRERALASLGKPLHPLLVVAPNQLKAWLQQYHNQCQEVLH
  HISMIPAKCLQEGAEISSPAVERLISSLLRTCDLEEFQTCLVRHCKHAFGCALVHTSGWKVVYSGDTMPC
  EALVRMGKDATLLIHEATLEDGLEEEAVEKTHSTTSQAISVGMRMNAEFIMLNHFSQRYAKVPLFSPNFS
  EKVGVAFDHMKVCFGDFPTMPKLIPPLKALFAGDIEEMEERREKRELRQVRAALLSRELAGGLEDGEPQQ
  KRAHTEEPQAKKVRAQ
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001165962
• ORF Size: 2358 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001165962.1, NP_001159434.1
• RefSeq Size: 3694
• RefSeq ORF: 2361
• Locus ID: 60528
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Gene Summary: The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]