ISYNA1 (NM_001170938) Human Tagged ORF Clone

CAT#: RG230189

ISYNA1 (GFP-tagged) - Human inositol-3-phosphate synthase 1 (ISYNA1), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: ISYNA1
• Synonyms: INO1; INOS; IPS; IPS-1; IPS 1
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG230189 representing NM_001170938
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGGCCGCCGCCCAGTTCTTCGTCGAGAGCCCGGACGTGGTCTACGGCCCCGAGGCCATCGAGGCGC
  AATACGAGTACCGGACGACGCGCGTCAGCCGCGAGGGTGGCGTTCTCAAGGAGGCCAACTACTACGGCTC
  GCTGACTCAGGCGGGCACCGTGAGCCTGGGCCTGGACGCCGAGGGCCAGGAGGTGTTCGTACCCTTCAGC
  GCGGTGCTGCCCATGGTGGCGCCCAACGACCTCGTGTTCGATGGCTGGGACATCTCGTCGCTGAACCTGG
  CCGAGGCGATGCGGCGCGCGAAGGTGCTGGACTGGGGGCTGCAGGAGCAACTGTGGCCGCACATGGAGGC
  CCTGCGGCCCCGGCCTTCTGTTTACATCCCCGAATTCATCGCGGCCAACCAGAGCGCGCGCGCGGACAAC
  CTCATCCCAGGCTCGCGTGCGCAGCAGCTGGAGCAGATCCGCAGGGACATCCGAGACTTCCGGTCTAGCG
  CGGGGCTGGACAAAGTCATAGTGCTGTGGACGGCGAACACGGAGCGCTTCTGTGAGGTGATTCCAGGCCT
  CAACGACACAGCCGAGAACCTGCTGCGCACCATTGAGCTCGGTCTGGAGGTGTCGCCCTCCACGCTCTTC
  GCCGTGGCCAGCATCCTGGAGGGCTGTGCCTTCCTCAATGGGTCTCCGCAGAACACCCTGGTGCCCGGAG
  CTCTTGAGCTCGCGTGGCAGCACCGGGTTTTTGTGGGCGGAGATGACTTCAAGTCAGGCCAGACCAAAGT
  CAAGTCCGTGCTTGTGGACTTCCTCATTGGCTCCGGCCTCAAGACCATGTCCATCGTGAGTTACAACCAC
  CTGGGCAACAACGATGGGGAGAACCTATCGGCGCCATTGCAGTTCCGCTCTAAGGAGGTGTCCAAGAGCA
  ACGTGGTGGACGACATGGTGCAGAGCAACCCAGTGCTCTATACGCCCGGCGAAGAGCCTGACCACTGCGT
  GGTCATCAAGTATGTGCCGTACGTGGGTGACAGCAAGCGCGCGCTGGATGAGTATACCTCGGAGCTGATG
  CTGGGCGGAACCAACACACTGGTGCTGCACAACACGTGTGAGGACTCGCTGCTGGCCGCACCCATCATGC
  TGGACCTAGCGCTGCTGACCGAGCTGTGCCAGCGCGTGAGCTTCTGCACTGACATGGACCCCGAGCCGCA
  GACCTTCCACCCCGTGCTGTCCCTGCTCAGCTTCCTCTTCAAGGCGCCACTAGTGCCGCCCGGCAGCCCG
  GTGGTCAATGCGCTTTTCCGCCAGCGCAGCTGCATCGAGAACATCCTCAGGGCCTGCGTGGGGCTCCCGC
  CACAGAACCACATGCTCCTGGAACACAAAATGGAGCGCCCAGGGCCCAGCCTCAAGCGAGTTGGACCCGT
  GGCTGCCACCTACCCTATGTTGAACAAGAAAGGACCGGTACCCGCTGCCACCAATGGCTGCACCGGTGAT
  GCCAATGGGCATCTGCAAGAGGAGCCCCCAATGCCCACCACC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG230189 representing NM_001170938
  Red=Cloning site Green=Tags(s)
  
  MEAAAQFFVESPDVVYGPEAIEAQYEYRTTRVSREGGVLKEANYYGSLTQAGTVSLGLDAEGQEVFVPFS
  AVLPMVAPNDLVFDGWDISSLNLAEAMRRAKVLDWGLQEQLWPHMEALRPRPSVYIPEFIAANQSARADN
  LIPGSRAQQLEQIRRDIRDFRSSAGLDKVIVLWTANTERFCEVIPGLNDTAENLLRTIELGLEVSPSTLF
  AVASILEGCAFLNGSPQNTLVPGALELAWQHRVFVGGDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNH
  LGNNDGENLSAPLQFRSKEVSKSNVVDDMVQSNPVLYTPGEEPDHCVVIKYVPYVGDSKRALDEYTSELM
  LGGTNTLVLHNTCEDSLLAAPIMLDLALLTELCQRVSFCTDMDPEPQTFHPVLSLLSFLFKAPLVPPGSP
  VVNALFRQRSCIENILRACVGLPPQNHMLLEHKMERPGPSLKRVGPVAATYPMLNKKGPVPAATNGCTGD
  ANGHLQEEPPMPTT
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001170938
• ORF Size: 1512 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001170938.1, NP_001164409.1
• RefSeq Size: 2265
• RefSeq ORF: 1515
• Locus ID: 51477
• Protein Families: Druggable Genome
• Protein Pathways: Inositol phosphate metabolism, Metabolic pathways
• Gene Summary: This gene encodes an inositol-3-phosphate synthase enzyme. The encoded protein plays a critical role in the myo-inositol biosynthesis pathway by catalyzing the rate-limiting conversion of glucose 6-phosphate to myoinositol 1-phosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011]