PREPL (NM_001171617) Human Tagged ORF Clone

CAT#: RG230379

PREPL (GFP-tagged) - Human prolyl endopeptidase-like (PREPL), transcript variant 7

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: PREPL
• Synonyms: CMS22
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG230379 representing NM_001171617
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGATGCATTTGAAAAAGTGAGAACAAAATTAGAAACACAGCCACAAGAAGAATATGAAATCATCAATG
  TGGAAGTTAAACATGGTGGTTTTGTTTATTACCAAGAAGGTTGTTGCTTGGTTCGTTCCAAAGATGAAGA
  AGCAGACAATGATAATTATGAAGTTTTATTCAATTTGGAGGAACTTAAGTTAGACCAGCCCTTCATTGAT
  TGTATCAGAGTTGCTCCAGATGAAAAATATGTGGCTGCCAAGATAAGAACTGAAGATTCTGAAGCATCTA
  CCTGTGTAATTATAAAGCTCAGCGATCAGCCCGTAATGGAAGCTTCTTTCCCGAATGTGTCCAGTTTTGA
  ATGGGTAAAGGACGAGGAAGATGAAGATGTTTTATTCTACACCTTCCAGAGGAACCTTCGCTGTCATGAC
  GTATATCGAGCCACTTTTGGTGATAACAAACGTAATGAACGCTTTTACACAGAAAAAGACCCAAGCTACT
  TTGTTTTCCTTTATCTTACAAAAGACAGTCGTTTCCTCACCATAAATATTATGAACAAGACTACTTCTGA
  AGTGTGGTTGATAGATGGCCTGAGCCCTTGGGACCCACCAGTACTTATCCAGAAGCGAATACATGGGGTC
  CTTTACTATGTTGAACACAGAGATGATGAATTATACATTCTCACTAATGTTGGAGAACCTACAGAATTTA
  AGCTAATGAGAACAGCGGCTGATACCCCTGCAATTATGAATTGGGATTTATTTTTTACAATGAAGAGAAA
  TACAAAAGTGATAGACTTGGACATGTTTAAGGATCACTGTGTTCTATTTCTGAAGCACAGCAATCTCCTT
  TATGTTAATGTGATTGGTCTGGCTGATGATTCAGTTCGGTCTCTAAAGCTCCCTCCTTGGGCCTGTGGAT
  TCATAATGGATACAAATTCTGACCCAAAGAACTGCCCCTTTCAACTTTGCTCTCCAATACGTCCCCCAAA
  ATATTACACATACAAGTTTGCAGAAGGCAAACTGTTTGAGGAAACTGGGCATGAAGACCCAATCACAAAG
  ACTAGTCGCGTTTTACGTCTAGAAGCCAAAAGCAAGGATGGAAAATTAGTGCCAATGACTGTTTTCCACA
  AAACTGACTCTGAGGACTTGCAGAAGAAACCTCTCTTGGTACATGTATATGGAGCTTATGGAATGGATTT
  GAAAATGAATTTCAGGCCTGAGAGGCGGGTCCTGGTGGATGATGGATGGATATTAGCATACTGCCATGTT
  CGAGGTGGTGGTGAGTTAGGCCTCCAGTGGCACGCTGATGGCCGCCTAACTAAAAAACTCAATGGCCTTG
  CTGATTTAGAGGCTTGCATTAAGACGCTTCATGGCCAAGGCTTTTCTCAGCCAAGTCTAACAACCCTGAC
  TGCTTTCAGTGCTGGAGGGGTGCTTGCAGGAGCATTGTGTAATTCTAATCCAGAGCTGGTGAGAGCGGTG
  ACTTTGGAGGCACCTTTCTTGGATGTTCTCAACACCATGATGGACACTACACTTCCTCTGACATTAGAAG
  AATTAGAAGAATGGGGGAATCCTTCATCTGATGAAAAACACAAGAACTACATAAAACGTTACTGTCCCTA
  TCAAAATATTAAACCTCAGCATTATCCTTCAATTCACATAACGGCATATGAAAACGATGAACGGGTACCT
  CTGAAAGGAATTGTAAGTTATACTGAGAAACTCAAGGAAGCCATCGCGGAGCATGCTAAGGACACAGGTG
  AAGGCTATCAGACCCCTAATATTATTCTAGATATTCAGCCTGGAGGCAATCATGTAATTGAGGATTCTCA
  CAAAAAGATTACAGCCCAAATTAAATTCCTGTACGAGGAACTTGGACTTGACAGCACCAGTGTTTTCGAG
  GATCTTAAGAAATACCTGAAATTC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG230379 representing NM_001171617
  Red=Cloning site Green=Tags(s)
  
  MDAFEKVRTKLETQPQEEYEIINVEVKHGGFVYYQEGCCLVRSKDEEADNDNYEVLFNLEELKLDQPFID
  CIRVAPDEKYVAAKIRTEDSEASTCVIIKLSDQPVMEASFPNVSSFEWVKDEEDEDVLFYTFQRNLRCHD
  VYRATFGDNKRNERFYTEKDPSYFVFLYLTKDSRFLTINIMNKTTSEVWLIDGLSPWDPPVLIQKRIHGV
  LYYVEHRDDELYILTNVGEPTEFKLMRTAADTPAIMNWDLFFTMKRNTKVIDLDMFKDHCVLFLKHSNLL
  YVNVIGLADDSVRSLKLPPWACGFIMDTNSDPKNCPFQLCSPIRPPKYYTYKFAEGKLFEETGHEDPITK
  TSRVLRLEAKSKDGKLVPMTVFHKTDSEDLQKKPLLVHVYGAYGMDLKMNFRPERRVLVDDGWILAYCHV
  RGGGELGLQWHADGRLTKKLNGLADLEACIKTLHGQGFSQPSLTTLTAFSAGGVLAGALCNSNPELVRAV
  TLEAPFLDVLNTMMDTTLPLTLEELEEWGNPSSDEKHKNYIKRYCPYQNIKPQHYPSIHITAYENDERVP
  LKGIVSYTEKLKEAIAEHAKDTGEGYQTPNIILDIQPGGNHVIEDSHKKITAQIKFLYEELGLDSTSVFE
  DLKKYLKF
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001171617
• ORF Size: 1914 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001171617.1, NP_001165088.1
• RefSeq Size: 6064
• RefSeq ORF: 1917
• Locus ID: 9581
• Protein Families: Druggable Genome, Protease
• Gene Summary: The protein encoded by this gene belongs to the prolyl oligopeptidase subfamily of serine peptidases. Mutations in this gene have been associated with hypotonia-cystinuria syndrome, also known as the 2p21 deletion syndrome. Several alternatively spliced transcript variants encoding either the same or different isoforms have been described for this gene. [provided by RefSeq, Jan 2010]