KIAA0319 (NM_001168376) Human Tagged ORF Clone

CAT#: RG230624

KIAA0319 (GFP-tagged) - Human KIAA0319 (KIAA0319), transcript variant 4

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: KIAA0319
• Synonyms: AAVR; DYLX2; DYX2; NMIG
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG230624 representing NM_001168376
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCGGGTGTCTCACACCTTCCCTGTCGTAGACTGCACGGCCGCTTGCTGTGACCTGTCCAGCTGTGACC
  TGGCCTGGTGGTTCGAGGGCCGCTGCTACCTGGTGAGCTGCCCCCACAAAGAGAACTGTGAGCCCAAGAA
  GATGGGCCCCATCAGGTCTTATCTCACTTTTGTGCTCCGGCCTGTTCAGAGGCCTGCACAGCTGCTGGAC
  TATGGGGACATGATGCTGAACAGGGGCTCCCCCTCGGGGATCTGGGGGGACTCACCTGAGGATATCAGAA
  AGGACTTGACCTTTCTAGGCAAAGATTGGGGCCTAGAGGAGATGTCTGAGTACTCAGATGACTACCGGGA
  GCTGGAGAAGGACCTCTTGCAACCCAGTGGCAAGCAGGAGCCCAGAGGGAGTGCCGAGTACACGGACTGG
  GGCCTACTGCCGGGCAGCGAGGGGGCCTTCAACTCCTCTGTTGGAGACAGTCCTGCGGTGCCAGCGGAGA
  CGCAGCAGGACCCTGAGCTCCATTACCTGAATGAGTCGGCTTCAACCCCTGCCCCAAAACTCCCTGAGAG
  AAGTGTGTTGCTTCCCTTGCCGACTACTCCATCTTCAGGAGAGGTGTTGGAGAAAGAAAAGGCTTCTCAG
  CTCCAGGAACAATCCAGCAACAGCTCTGGAAAAGAGGTTCTAATGCCTTCCCATAGTCTTCCTCCGGCAA
  GCCTGGAGCTCAGCTCAGTCACCGTGGAGAAAAGCCCAGTGCTCACAGTCACCCCGGGGAGTACAGAGCA
  CAGCATCCCAACACCTCCCACTAGCGCAGCCCCCTCTGAGTCCACCCCATCTGAGCTACCCATATCTCCT
  ACCACTGCTCCCAGGACAGTGAAAGAACTTACGGTATCGGCTGGAGATAACCTAATTATAACTTTACCCG
  ACAATGAAGTTGAACTGAAGGCCTTTGTTGCGCCAGCGCCACCTGTAGAAACAACCTACAACTATGAATG
  GAATTTAATAAGCCACCCCACAGACTACCAAGGTGAAATAAAACAAGGACACAAGCAAACTCTTAACCTC
  TCTCAATTGTCCGTCGGACTTTATGTCTTCAAAGTCACTGTTTCTAGTGAAAACGCCTTTGGAGAAGGAT
  TTGTCAATGTCACTGTTAAGCCTGCCAGAAGAGTCAACCTGCCACCTGTAGCAGTTGTTTCTCCCCAACT
  GCAAGAGCTCACTTTGCCTTTGACGTCAGCCCTCATTGATGGCAGCCAAAGTACAGATGATACTGAAATA
  GTGAGTTATCATTGGGAAGAAATAAACGGGCCCTTCATAGAAGAGAAGACTTCAGTTGACTCTCCCGTCT
  TACGCTTGTCTAACCTTGATCCTGGTAACTATAGTTTCAGGTTGACTGTTACAGACTCGGACGGAGCCAC
  TAACTCTACAACTGCAGCCCTAATAGTGAACAATGCTGTGGACTACCCACCAGTTGCTAATGCAGGACCA
  AATCACACCATAACTTTGCCCCAAAACTCCATCACTTTGAATGGAAACCAGAGCAGTGACGATCACCAGA
  TTGTCCTCTATGAGTGGTCCCTGGGTCCTGGGAGTGAGGGCAAACATGTGGTCATGCAGGGAGTACAGAC
  GCCATACCTTCATTTATCTGCAATGCAGGAAGGAGATTATACATTTCAGCTGAAGGTGACAGATTCTTCA
  AGGCAACAGTCTACTGCTGTGGTGACTGTGATTGTCCAGCCTGAAAACAATAGACCTCCAGTGGCTGTGG
  CCGGCCCTGATAAAGAGCTGATCTTCCCAGTGGAAAGTGCTACCCTGGATGGGAGCAGCAGCAGCGATGA
  CCACGGCATTGTCTTCTACCACTGGGAGCACGTCAGAGGCCCCAGTGCAGTGGAGATGGAAAATATTGAC
  AAAGCAATAGCCACTGTGACTGGTCTCCAGGTGGGGACCTACCACTTCCGTTTGACAGTGAAAGACCAGC
  AGGGACTGAGCAGCACGTCCACCCTCACTGTGGCTGTGAAGAAGGAAAATAATAGTCCTCCCAGAGCCCG
  GGCTGGTGGCAGACATGTTCTTGTGCTTCCCAATAATTCCATTACTTTGGATGGTTCAAGGTCTACTGAT
  GACCAAAGAATTGTGTCCTATCTGTGGATCCGGGATGGCCAGAGTCCAGCAGCTGGAGATGTCATCGATG
  GCTCTGACCACAGTGTGGCTCTGCAGCTTACGAATCTGGTGGAGGGGGTGTACACTTTCCACTTGCGAGT
  CACCGACAGTCAGGGGGCCTCGGACACAGACACTGCCACTGTGGAAGTGCAGCCAGACCCTAGGAAGAGT
  GGCCTGGTGGAGCTGACCCTGCAGGTTGGTGTTGGGCAGCTGACAGAGCAGCGGAAGGACACCCTTGTGA
  GGCAGCTGGCTGTGCTGCTGAACGTGCTGGACTCGGACATTAAGGTCCAGAAGATTCGGGCCCACTCGGA
  TCTCAGCACCGTGATTGTGTTTTATGTACAGAGCAGGCCGCCTTTCAAGGTTCTCAAAGCTGCTGAAGTG
  GCCCGAAATCTGCACATGCGGCTCTCAAAGGAGAAGGCTGACTTCTTGCTTTTCAAGGTCTTGAGGGTTG
  ATACAGCAGGTTGCCTTCTGAAGTGTTCTGGCCATGGTCACTGCGACCCCCTCACAAAGCGCTGCATTTG
  CTCTCACTTATGGATGGAGAACCTTATACAGCGTTATATCTGGGATGGAGAGAGCAACTGTGAGTGGAGT
  ATATTCTATGTGACAGTGTTGGCTTTTACTCTTATTGTGCTAACAGGAGGTTTCACTTGGCTTTGCATCT
  GCTGCTGCAAAAGACAAAAAAGGACTAAAATCAGGAAAAAAACAAAGTACACCATCCTGGATAACATGGA
  TGAACAGGAAAGAATGGAACTGAGGCCCAAATATGGTATCAAGCACCGAAGCACAGAGCACAACTCCAGC
  CTGATGGTATCCGAGTCTGAGTTTGACAGTGACCAGGACACAATCTTCAGCCGAGAAAAGATGGAGAGAG
  GGAATCCAAAGGTTTCCATGAATGGTTCCATCAGAAATGGAGCTTCCTTCAGTTATTGCTCAAAGGACAG
  A
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG230624 representing NM_001168376
  Red=Cloning site Green=Tags(s)
  
  MRVSHTFPVVDCTAACCDLSSCDLAWWFEGRCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLD
  YGDMMLNRGSPSGIWGDSPEDIRKDLTFLGKDWGLEEMSEYSDDYRELEKDLLQPSGKQEPRGSAEYTDW
  GLLPGSEGAFNSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPTTPSSGEVLEKEKASQ
  LQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGSTEHSIPTPPTSAAPSESTPSELPISP
  TTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAPAPPVETTYNYEWNLISHPTDYQGEIKQGHKQTLNL
  SQLSVGLYVFKVTVSSENAFGEGFVNVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEI
  VSYHWEEINGPFIEEKTSVDSPVLRLSNLDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGP
  NHTITLPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLKVTDSS
  RQQSTAVVTVIVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHWEHVRGPSAVEMENID
  KAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPRARAGGRHVLVLPNNSITLDGSRSTD
  DQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTNLVEGVYTFHLRVTDSQGASDTDTATVEVQPDPRKS
  GLVELTLQVGVGQLTEQRKDTLVRQLAVLLNVLDSDIKVQKIRAHSDLSTVIVFYVQSRPPFKVLKAAEV
  ARNLHMRLSKEKADFLLFKVLRVDTAGCLLKCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWS
  IFYVTVLAFTLIVLTGGFTWLCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRSTEHNSS
  LMVSESEFDSDQDTIFSREKMERGNPKVSMNGSIRNGASFSYCSKDR
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001168376
• ORF Size: 3081 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001168376.1, NP_001161848.1
• RefSeq Size: 6620
• RefSeq ORF: 3084
• Locus ID: 9856
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a transmembrane protein that contains a large extracellular domain with multiple polycystic kidney disease (PKD) domains. The encoded protein may play a role in the development of the cerebral cortex by regulating neuronal migration and cell adhesion. Single nucleotide polymorphisms in this gene are associated with dyslexia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]