NEIL1 (NM_001256552) Human Tagged ORF Clone

CAT#: RG232817

NEIL1 (GFP-tagged) - Homo sapiens nei endonuclease VIII-like 1 (E. coli) (NEIL1), transcript variant 1

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: NEIL1
• Synonyms: FPG1; hFPG1; NEI1
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG232817 representing NM_001256552
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGGAGGACGGGCCCGAGAGCGCCGCTCCTCCCCAAAACTAGGATTTGGAGCCTCACGTTCTCCCGCA
  AAACGAGCCCTGTGGGTGCCAGGCCAGGGGCGGCTCCCAGGTGTGGAGGGGGCAAGGTACGGGCGTCTGC
  CGTCGCTAAGTGCCCCCTTCCACTTAAGGCACACCTTCGCCTCCGATTCCGAACCGCCCGGGGACAGAGG
  CAAGTGGCAAAGCAGGGAGGGCGGAGGACTCTGCCACCCTCCCTCAGGATGCCTGAGGGCCCCGAGCTGC
  ACCTGGCCAGCCAGTTTGTGAATGAGGCCTGCAGGGCGCTGGTGTTCGGCGGCTGCGTGGAGAAGTCCTC
  TGTCAGCCGCAACCCTGAGGTGCCCTTTGAGAGCAGTGCCTACCGCATCTCAGCTTCAGCCCGCGGCAAG
  GAGCTGCGCCTGATACTGAGCCCTCTGCCTGGGGCCCAGCCCCAACAGGAGCCACTGGCCCTGGTCTTCC
  GCTTCGGCATGTCCGGCTCTTTTCAGCTGGTGCCCCGCGAGGAGCTGCCACGCCATGCCCACCTGCGCTT
  TTACACGGCCCCGCCTGGCCCCCGGCTCGCCCTATGTTTCGTGGACATCCGCCGGTTCGGCCGCTGGGAC
  CTTGGGGGAAAGTGGCAGCCGGGCCGCGGGCCCTGTGTCTTGCAGGAGTACCAGCAGTTCAGGGAGAATG
  TGCTACGAAACCTAGCGGATAAGGCCTTTGACCGGCCCATCTGCGAGGCCCTCCTGGACCAGAGGTTCTT
  CAATGGCATTGGCAACTATCTGCGGGCAGAGATCCTGTACCGGCTGAAGATCCCCCCCTTTGAGAAGGCC
  CGCTCGGTCCTGGAGGCCCTGCAGCAGCACAGGCCGAGCCCGGAGCTGACCCTGAGCCAGAAGATAAGGA
  CCAAGCTGCAGAATCCAGACCTGCTGGAGCTATGTCACTCAGTGCCCAAGGAAGTGGTCCAGTTGGGGGG
  CAAAGGCTACGGGTCAGAGAGCGGGGAGGAGGACTTTGCTGCCTTTCGAGCCTGGCTGCGCTGCTATGGC
  ATGCCAGGCATGAGCTCCCTGCAGGACCGGCATGGCCGTACCATCTGGTTCCAGGGGGATCCTGGACCGT
  TGGCACCCAAAGGGCGCAAGTCCCGCAAAAAGAAATCCAAGGCCACACAGCTGAGTCCTGAGGACAGAGT
  GGAGGACGCTTTGCCTCCAAGCAAGGCCCCTTCCAGGACACGAAGGGCAAAGAGAGACCTTCCTAAGAGG
  ACTGCAACCCAGCGGCCTGAGGGGACCAGCCTCCAGCAGGACCCAGAAGCTCCCACAGTGCCCAAGAAGG
  GGAGGAGGAAGGGGCGACAGGCAGCCTCTGGCCACTGCAGACCCCGGAAGGTCAAGGCTGACATCCCATC
  CTTGGAACCAGAGGGGACCTCAGCCTCT
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG232817 representing NM_001256552
  Red=Cloning site Green=Tags(s)
  
  MGRTGPRAPLLPKTRIWSLTFSRKTSPVGARPGAAPRCGGGKVRASAVAKCPLPLKAHLRLRFRTARGQR
  QVAKQGGRRTLPPSLRMPEGPELHLASQFVNEACRALVFGGCVEKSSVSRNPEVPFESSAYRISASARGK
  ELRLILSPLPGAQPQQEPLALVFRFGMSGSFQLVPREELPRHAHLRFYTAPPGPRLALCFVDIRRFGRWD
  LGGKWQPGRGPCVLQEYQQFRENVLRNLADKAFDRPICEALLDQRFFNGIGNYLRAEILYRLKIPPFEKA
  RSVLEALQQHRPSPELTLSQKIRTKLQNPDLLELCHSVPKEVVQLGGKGYGSESGEEDFAAFRAWLRCYG
  MPGMSSLQDRHGRTIWFQGDPGPLAPKGRKSRKKKSKATQLSPEDRVEDALPPSKAPSRTRRAKRDLPKR
  TATQRPEGTSLQQDPEAPTVPKKGRRKGRQAASGHCRPRKVKADIPSLEPEGTSAS
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001256552
• ORF Size: 1428 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001256552.1, NP_001243481.1
• RefSeq Size: 1820
• RefSeq ORF: 1431
• Locus ID: 79661
• Protein Families: Druggable Genome
• Protein Pathways: Base excision repair
• Gene Summary: This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]